No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Organic D-Mannose Powder Ingredients & Drug Interactions

by Micro Ingredients

Powder Category: Fiber And Other Nutrients
No known interaction
The interaction bottom line No known interaction

Organic D-Mannose Powder is a dietary supplement by Micro Ingredients with 2 active ingredients. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Organic D-Mannose Powder by Micro Ingredients

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-mannose, a simple sugar that your body doesn't fully break down the way it does glucose. The powder contains no other inactive ingredients — it's D-mannose alone.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: supports urinary tract health.
  • We looked for evidence on: Urinary tract infections (UTIs), urinary tract infection prevention, bladder health, uroepithelial health.
  • The closest evidence on file: D-mannose is rated "Possibly Ineffective" for Urinary tract infections (UTIs) (Natural Medicines).

D-mannose is rated likely effective for carbohydrate-deficient glycoprotein syndrome type 1b, a rare metabolic condition. For urinary tract infections (UTIs), the evidence rates it as possibly ineffective — meaning the data we hold doesn't support its use for that purpose, even though it's often marketed for it.

The evidence, ingredient by ingredient D-mannose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-mannose is generally well tolerated in the short term, but high-quality long-term safety data are limited. The most common side effects are bloating, diarrhea, and nausea.

Diarrhea risk goes up with larger single doses — particularly doses over 200 mg per kilogram of body weight — because of the way the sugar works in your intestines. Safety during pregnancy isn't well studied enough to advise one way or the other — talk with your doctor or pharmacist about whether it's right for you.

Safety while breastfeeding is also not well studied, so caution is advised if you're nursing.

Side effects, ingredient by ingredient D-mannose

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we could check. That said, confirm with your pharmacist before starting, especially if you take multiple medications or have digestive sensitivities.

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

D-mannose is primarily supported by evidence for a specific rare metabolic disorder, not for UTIs. It's generally tolerated short-term but can cause digestive upset — especially diarrhea at higher doses.

If you're pregnant, nursing, or taking it long-term, talk with your doctor or pharmacist first to make sure it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic D-Mannose Powder, straight from the product label.

Brand Micro Ingredients
Barcode (UPC) X0016XQT2J
Net contents 250 Gram(s); 8.82 Ounce(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 231542
Product type Fiber And Other Nutrients
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic D-Mannose Powder by Micro Ingredients, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
125
UPC/BARCODE
X0016XQT2J
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates2 Gram(s)--
Sugar2 Gram(s)--
D-Mannose2 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

USDA Organic

Kosher

Formulation

USDA Organic

Supports urinary tract health

Non-GMO No preservatives Additives free Fillers free Gluten-free

Free of: soy, dairy, yeast, gluten & additives.

Certified organic by Organic Certifiers

FDA Statement of Identity

Dietary Supplement

Formula

Kosher

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 scoop twice daily with water, or as directed by a physician.

Precautions

Keep out of the reach of children.

If pregnant/lactating or taking any medications, please consult your physician prior to use.

Storage

Keep in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Organic D-Mannose Powder by Micro Ingredients label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic D-Mannose Powder by Micro Ingredients

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container125 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

2 Gram(s) per serving

D-Mannose

No known
interactions
2 Gram(s) per serving

D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...

D-Mannose monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic D-Mannose Powder by Micro Ingredients Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Organic D-Mannose Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Organic D-Mannose Powder, from the product label.

Micro Ingredients

See all Micro Ingredients products
Name
Micro Ingredients
Street Address
21660 Copley Dr.
City
Diamond Bar
State
CA
ZipCode
91765
Phone Number
1-844-836-8200
Web Address
www.microingredients.com
Pharmacist Counseling Corner

Organic D-Mannose Powder by Micro Ingredients: Common Questions

Does Organic D-Mannose Powder by Micro Ingredients interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Organic D-Mannose Powder. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Organic D-Mannose Powder contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does D-mannose actually work for UTIs?
The evidence we hold rates it as possibly ineffective for urinary tract infections. That means the data doesn't support its use for that purpose, even though it's often marketed for UTI prevention. Talk with your doctor if you're considering it for a UTI.
What are the most common side effects?
Bloating, diarrhea, and nausea are the most common when you take it by mouth. Diarrhea and loose stools are more likely if you take a larger single dose — especially over 200 mg per kilogram of your body weight.
Is it safe to take long-term?
It's generally well tolerated short-term, but high-quality long-term safety data are limited. If you're thinking about taking it regularly, check with your doctor or pharmacist first.
Can I take it while pregnant?
There isn't enough reliable safety data to say either way. Talk with your doctor about whether it's right for you during pregnancy.
Is it safe while breastfeeding?
Safety while breastfeeding is not well studied, so caution is advised. Discuss it with your doctor or pharmacist to decide what's best for you and your baby.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic D-Mannose Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic D-Mannose Powder label
Go deeper

The Full Monographs Behind Organic D-Mannose Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Organic D-Mannose Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

D-mannose 6 references
  1. Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
  2. Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
  3. de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
  4. Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
  5. . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
  6. Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed

See these in context on the D-mannose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring