Panex 8 Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Panex 8 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Panex 8 is a dietary supplement by MBi Nutraceuticals with 4 active ingredients. Its ingredients are commonly taken for swelling and inflammation after injury or surgery, wound healing, cataract surgery (intracapsular).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Panex 8 by MBi Nutraceuticals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Panex 8 contains 4 active ingredients: chymotrypsin and trypsin, which are digestive enzymes that help break down proteins; pancreatin, a pancreatic enzyme blend; and bile, which supports fat digestion. The product also contains two inactive ingredients — magnesium stearate and silica — that act as binders and flow agents in the capsule.
Does it work?
Couldn't assess
Chymotrypsin is rated effective for cataracts. For burns, fractures, and chronic obstructive parotitis, the evidence is insufficient to rate it.
Trypsin has insufficient reliable evidence to rate it for sprains, osteoarthritis, radiation dermatitis, wound healing, exercise-induced muscle soreness, or multiple sclerosis. We hold no effectiveness data for pancreatin or bile in our records.
How safe is it?
Well-documented data
Chymotrypsin and trypsin are generally tolerated for short-term use, but quality evidence is limited and some people may react to these animal-derived enzymes. Both can cause gastrointestinal upset — chymotrypsin through hypersensitivity reactions, trypsin through mild-to-moderate nausea, heartburn, or stomach pain when taken with other enzymes.
Rarely, chymotrypsin has triggered anaphylaxis (a severe allergic reaction with breathing trouble, swelling, and shock). Trypsin applied topically can cause localized pain and burning.
Do not use during pregnancy or while breastfeeding — safety data is not established for either ingredient in these situations.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. We cannot confirm interaction status for pancreatin and bile.
Run your exact medications through the interaction checker on this page, and confirm with your doctor or pharmacist before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Panex 8 may be worth considering if you're interested in digestive enzyme support, though evidence for most of its claimed uses is limited. Because you're taking animal-derived enzymes, watch for any signs of allergic reaction — especially if you've had reactions to digestive supplements before.
Talk with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have a history of severe allergies.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Panex 8, straight from the product label.
| Brand | MBi Nutraceuticals |
|---|---|
| Barcode (UPC) | 358301224183 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 231767 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Panex 8 by MBi Nutraceuticals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Chymotrypsin | 0 NP | -- |
| Trypsin | 0 NP | -- |
| Proprietary Digestive Blend | 725 mg | -- |
| Pancreatin | 0 NP | -- |
| Bile | 0 NP | -- |
Other ingredients: Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Panex-8 is a special formula containing a digestive enzyme from the pancreas and is a remedy for lower gastrointestinal tract digestive problems. It is especially helpful for treating upset stomach related to food allergies.
Suggested/Recommended/Usage/Directions
Recommendation: Take one capsule after meals or as directed by your health care professional.
Precautions
Do not exceed three capsules per day.
Warning: If pregnant or nursing, please consult your physician before using this product.
If diarrhea results from the use of this product, discontinue use until condition subsides.
Keep out of the reach of children.
If tamper resistant seals are broken do not use this product.
FDA Statement of Identity
Digestive Enzyme Supplement with Pancreatin 8X
General Statements
Bringing balance back to life
Typical enzyme activity per capsule: Amylase 160,000 NFU, Lipase 25,000 NFU, Protease 150,000 NFU.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Panex 8 by MBi Nutraceuticals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Panex 8 by MBi Nutraceuticals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Digestive Blend
- › Chymotrypsin
- › Trypsin
- › Pancreatin
- › Bile
Other (inactive) ingredients: Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Panex 8 by MBi Nutraceuticals Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Panex 8. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Panex 8, from the product label.
MBi Nutraceuticals
See all MBi Nutraceuticals products- Name
- MBi Nutraceuticals
- Street Address
- 211 N 1800 W
- City
- Lindon
- State
- UT
- ZipCode
- 84042
- Phone Number
- 801-796-8742
Panex 8 by MBi Nutraceuticals: Common Questions
Does Panex 8 by MBi Nutraceuticals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is chymotrypsin safe to take if I'm pregnant?
What does trypsin do in this product?
Can this product cause stomach upset?
Is Panex 8 safe to breastfeed while taking?
Does this product work for burns or fractures?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Panex 8 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Panex 8’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chymotrypsin
Chymotrypsin is a protein-digesting (proteolytic) enzyme, usually taken from the pancreas of cattle or pigs, that is mainly used to help reduce swelling and support healing after injury or s...
Read the full Chymotrypsin monograph → Herb & supplement monographTrypsin
Trypsin is a protein-digesting enzyme usually taken from the pancreas of animals and used either by mouth (often combined with other enzymes like chymotrypsin and bromelain) for swelling and...
Read the full Trypsin monograph →Sources & How We Checked
Panex 8's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chymotrypsin 6 references
- Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
- Dukes, MNG. Meyler's Side Effects of Drugs. 13th ed. Elsevier: Amsterdam, 1997.
- Latha B, Ramakrishnan M, Jayaraman V, Babu M. Serum enzymatic changes modulated using trypsin: chymotrypsin preparation during burn wounds in humans. Burns 1997;23:560-4. PubMed
- Shaw PC. The use of a trypsin-chymotrypsin formulation in fractures of the hand. Br J Clin Pract 1969;23:25-6. DOI
- McCue FC, Webster TM, Gieck J. Clinical effects of proteolytic enzymes after reconstructive hand surgery. Int Surg 1972;57:479-82.
- Sun HJ, Xiao JQ, Qiao QH, et al. Chymotrypsin with sialendoscopy-assisted surgery for the treatment of chronic obstructive parotitis. Int J Oral Maxillofac Surg 2017;46(7):877-82. doi: 10.1016/j.ijom.2017.02.1267. PubMed
Trypsin 17 references
- Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
- Latha B, Ramakrishnan M, Jayaraman V, Babu M. The efficacy of trypsin: chymotrypsin preparation in the reduction of oxidative damage during burn injury. Burns 1998;24:532-8. PubMed
- Latha B, Ramakrishnan M, Jayaraman V, Babu M. Serum enzymatic changes modulated using trypsin: chymotrypsin preparation during burn wounds in humans. Burns 1997;23:560-4. PubMed
- Klein, G., Kullich, W., Schnitker, J., and Schwann, H. Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A double-blind, randomised study comparing oral enzymes with non-steroidal anti-inflammatory drugs. Clin Exp
- Dale, P. S., Tamhankar, C. P., George, D., and Daftary, G. V. Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects. Cancer Chemother.Pharmacol 2001;47 Suppl:S29-S34. PubMed
- Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
- Miller, P. C., Bailey, S. P., Barnes, M. E., Derr, S. J., and Hall, E. E. The effects of protease supplementation on skeletal muscle function and DOMS following downhill running. J Sports Sci 2004;22(4):365-372. PubMed
- Bolten WW, Glade MJ, Raum S, Ritz BW. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial. Arthritis 2015;2015:251521. PubMed
- US Department of Justice. U.S. Files Complaint Against Texas-Based Healthpoint Ltd. Under the False Claims Act. https://www.justice.gov/opa/pr/us-files-complaint-against-texas-based-healthpoint-ltd-under-false-claims-act. (Accessed June 19, 2019).
- Grabs V, Kersten A, Haller B, et al. Rutoside and hydrolytic enzymes do not attenuate marathon-induced inflammation. Med Sci Sports Exerc. 2017;49(3):387-395. PubMed
- Baumhackl U, Kappos L, Radue EW, et al. A randomized, double-blind, placebo-controlled study of oral hydrolytic enzymes in relapsing multiple sclerosis. Mult Scler. 2005;11(2):166-8. PubMed
- Gujral MS, Patnaik PM, Kaul R, et al. Efficacy of hydrolytic enzymes in preventing radiation therapy-induced side effects in patients with head and neck cancers. Cancer Chemother Pharmacol. 2001;47 Suppl:S23-8. PubMed
- Kempf K, Manzo G, Hanifi-Moghaddam P, et al. Effect of combined oral proteases and flavonoid treatment in subjects at risk of Type 1 diabetes. Diabet Med. 2009;26(12):1309-10. PubMed
- Kerkhoffs GM, Struijs PA, de Wit C, Rahlfs VW, Zwipp H, van Dijk CN. A double blind, randomised, parallel group study on the efficacy and safety of treating acute lateral ankle sprain with oral hydrolytic enzymes. Br J Sports Med. 2004;38(4):431-5. PubMed
- Popiela T, Kulig J, Klek S, Wachol D, Bock PR, Hanisch J. Double-blind pilot-study on the efficacy of enzyme therapy in advanced colorectal cancer. Przegl Lek. 2000;57 Suppl 5:142.
- Shetty V, Mohan A. A prospective, randomized, double-blind, placebo-controlled clinical trial comparing the efficacy of systemic enzyme therapy for edema control in orthognathic surgery using ultrasound scan to measure facial swelling. J Oral Maxillofac S PubMed
- Comparison of Chronic Wound Care Products. Pharmacist's Letter/Prescriber's Letter 2008;12(3):1203.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC