No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pantothenic Acid 500 mg Ingredients & Drug Interactions

by Metabolic Maintenance

Pantothenic Acid 500 mg label
See full label image
Capsule Category: Vitamin
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pantothenic Acid 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Pantothenic Acid 500 mg is a dietary supplement by Metabolic Maintenance with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Pantothenic Acid 500 mg by Metabolic Maintenance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: 500 mg of pantothenic acid (vitamin B5), a B-complex vitamin your body uses for energy production and the breakdown of fats and carbohydrates. The capsule itself is made from vegetarian cellulose, and there's a small amount of L-leucine (an amino acid) as an inactive ingredient.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Pantothenic Acid's overall clinical evidence instead.

Strong

Strong clinical evidence supports Pantothenic Acid for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Pantothenic acid deficiency — rated "Effective" (Natural Medicines).

Pantothenic acid is effective for treating pantothenic acid deficiency—a genuine but rare shortage of this vitamin. For other uses, the evidence is thinner.

It's rated possibly ineffective for radiation dermatitis. For hay fever, alcoholism, and alopecia areata (patchy hair loss), there isn't enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Pantothenic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, pantothenic acid is generally well tolerated at typical supplement doses. The most common side effect reported is diarrhea.

According to the safety data, amounts you'd get from food or prenatal vitamins are appropriate, but if you're considering a high-dose supplement like this one, check with your doctor first. In pregnancy and breastfeeding, pantothenic acid is rated likely safe at normal dietary and prenatal-vitamin levels.

Before taking a 500 mg supplement during pregnancy or while nursing, talk with your doctor or pharmacist about whether that dose makes sense for you.

Side effects, ingredient by ingredient Pantothenic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the pantothenic acid we hold data on. That doesn't mean none exist—it means none have been flagged in the evidence we have access to.

If you're on any regular medications, it's still worth a quick conversation with your pharmacist to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward B5 supplement, most useful if you have a documented deficiency or want general B-vitamin support. It's well tolerated in most people, but high doses aren't routinely studied.

If you're pregnant, nursing, or take any medications regularly, check with your doctor or pharmacist before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pantothenic Acid 500 mg, straight from the product label.

Brand Metabolic Maintenance
Barcode (UPC) 838287006367
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 274089
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pantothenic Acid 500 mg by Metabolic Maintenance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
838287006367
IngredientAmount% DV
Pantothenic Acid500 mg10000%

Other ingredients: Vegetarian Cellulose Capsule, L-Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Caution: Pregnant or lactating women, consult your healthcare professional before taking this product.

Keep tightly closed in a cool, dry place, out of the reach of children.

Storage

Keep tightly closed in a cool, dry place, out of the reach of children.

Formulation

Egg free Gluten free Free of nuts Dairy free

Manufactured in a GMP Compliant Facility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: One to two (1-2) capsules daily with a meal, or as directed by a healthcare professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pantothenic Acid 500 mg by Metabolic Maintenance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pantothenic Acid 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pantothenic Acid 500 mg by Metabolic Maintenance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Pantothenic Acid

No known
interactions
500 mg per serving Form: Calcium D-Pantothenate

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

Other (inactive) ingredients: Vegetarian Cellulose Capsule, L-Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pantothenic Acid 500 mg by Metabolic Maintenance Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pantothenic Acid 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pantothenic Acid 500 mg, from the product label.

Metabolic Maintenance

See all Metabolic Maintenance products
Name
Metabolic Maintenance
Street Address
601 N Larch Street
City
Sisters
State
Oregon
ZipCode
97759
Phone Number
800-772-7873
Web Address
MetabolicMaintenance.com
Pharmacist Counseling Corner

Pantothenic Acid 500 mg by Metabolic Maintenance: Common Questions

Does Pantothenic Acid 500 mg by Metabolic Maintenance interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pantothenic Acid 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pantothenic Acid 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my hair grow or stop hair loss?
There isn't enough reliable evidence to say whether pantothenic acid works for alopecia areata (patchy hair loss). If hair loss is a concern, talk with your doctor about what's actually driving it and what evidence-based options might help.
Can I take this if I'm pregnant or breastfeeding?
Pantothenic acid is rated likely safe during pregnancy and breastfeeding at normal dietary levels and the amounts in prenatal vitamins. A 500 mg supplement is a higher dose, though, so check with your doctor or pharmacist first to make sure it's right for your situation.
What does pantothenic acid actually do?
Pantothenic acid (B5) is a B-complex vitamin your body uses to produce energy and break down fats and carbohydrates. Most people get enough from food, but this supplement is useful if you have a documented deficiency.
What are the side effects?
Orally, pantothenic acid is generally well tolerated. The most commonly reported side effect is diarrhea. Serious side effects are rare at typical supplement doses.
Is this safe for everyday use?
Pantothenic acid is considered safe for most people at typical supplement doses. That said, if you're taking high-dose supplements regularly, it's worth checking in with your doctor, especially if you're pregnant, nursing, or have any underlying health conditions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pantothenic Acid 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pantothenic Acid 500 mg label
Go deeper

The Full Monographs Behind Pantothenic Acid 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph →
Sources

Sources & How We Checked

Pantothenic Acid 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pantothenic Acid 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
  5. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
  6. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
  7. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  8. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
  9. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
  10. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
  11. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed

See these in context on the Pantothenic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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