Interaction check not available yet — this product's ingredients haven't been matched to our database.
Dietary supplement

PF DigestChew Natural Cherry Flavor Ingredients & Drug Interactions

by PureFormulas

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

PF DigestChew Natural Cherry Flavor is a dietary supplement by PureFormulas with 6 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of PF DigestChew Natural Cherry Flavor by PureFormulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 17 active ingredients.
  • “Comprehensive Enzyme Blend” is a proprietary blend — the label gives one combined amount (320 mg) without saying how much of each component you get.
  • “Carbohydrate Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Sugar Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

PF DigestChew contains 17 ingredients, mostly digestive enzymes organized into functional groups. The checked enzymes include Lipase (breaks down fats), Lactase (breaks down milk sugar), Acid Protease and Alkaline Protease (break down proteins), and Phytase (helps with mineral absorption).

Several others—Amylase, Serratiopeptidase, Cellulase, Glucoamylase, Maltase, and more—are also present but we hold no interaction data for them. The tablet also contains inactive ingredients like xylitol, mannitol, and natural cherry flavor for taste and texture.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Comprehensive digestive enzyme support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating and gas.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence we hold rates Lactase as effective for lactose intolerance (trouble digesting milk sugar). For Lipase, Phytase, Acid Protease, and Alkaline Protease, the data shows insufficient reliable evidence to rate their effectiveness for any condition.

We have no effectiveness ratings on file for most of the other enzymes in the blend.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase, Lactase, Acid Protease, Alkaline Protease, and Phytase are generally well tolerated in the amounts used as supplements, though digestive upset or allergic reactions are possible with proteolytic enzymes (the protein-breaking ones). A rare case of contact dermatitis from powdered lactase has been reported in a workplace setting, and occupational exposure to airborne proteolytic enzymes has caused allergic reactions in some workers.

For pregnancy, the data is mixed: Lactase is likely safe, but there isn't enough safety information for Lipase, the proteases, or Phytase—talk with your doctor before using this product regularly during pregnancy or breastfeeding.

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, we hold no interaction data for several enzymes in this product, so you should verify your exact medications with your doctor or pharmacist before taking it.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This digestive enzyme blend may help with lactose intolerance, though evidence for the other enzymes is limited. If you have a serious digestive condition, check with your doctor or pharmacist first.

Since we cannot check many of the enzymes in this product for drug interactions, run your medications through the tool on this page before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 17 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PF DigestChew Natural Cherry Flavor, straight from the product label.

Brand PureFormulas
Barcode (UPC) 828054735996
Net contents 180 Chewable Tablet(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 205877
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PF DigestChew Natural Cherry Flavor by PureFormulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
90
UPC/BARCODE
828054735996
IngredientAmount% DV
Amylase0 NP--
Serratiopeptidase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Glucoamylase0 NP--
Maltase0 NP--
Acid Protease0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Alpha-Amylase0 NP--
Sucrase0 NP--
Alkaline Protease0 NP--
Comprehensive Enzyme Blend320 mg--
Carbohydrate Specific Enzymes0 NP--
Sugar Specific Enzymes0 NP--
Pullulanase0 NP--
Vegetable/Plant Fiber Specific Enzymes0 NP--
Galactomannase0 NP--
Protein and Peptide Specific Enzymes0 NP--
Fat Specific Enzymes0 NP--
Other Enzymes0 NP--
Hemicellulase/Pectinase/Phytase Complex0 NP--
Protease/Peptidase Complex0 NP--

Other ingredients: Xylitol, Mannitol, Stearic Acid, Silicon Dioxide, natural Cherry flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Live life pure.

Units are those used in edition five (V) of the Food Chemicals Codex (FCC)

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.

FDA Statement of Identity

Comprehensive Enzyme Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 2 tablets at the beginning of each meal.

Brand IP Statement(s)

Peptizyme SP, a registered trademark of Specialty Enzymes

Precautions

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

Storage

Store in a cool, dry place (59(0)F-85(0)F) away from direct light.

See for yourself

PF DigestChew Natural Cherry Flavor by PureFormulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PF DigestChew Natural Cherry Flavor by PureFormulas

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Comprehensive Enzyme Blend

320 mg per serving
  • › Carbohydrate Specific Enzymes
  • › Sugar Specific Enzymes
  • › Vegetable/Plant Fiber Specific Enzymes
  • › Protein and Peptide Specific Enzymes
  • › Fat Specific Enzymes
  • › Other Enzymes

Other (inactive) ingredients: Xylitol, Mannitol, Stearic Acid, Silicon Dioxide, Natural Cherry flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

PF DigestChew Natural Cherry Flavor by PureFormulas Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in PF DigestChew Natural Cherry Flavor. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for PF DigestChew Natural Cherry Flavor, from the product label.

PureFormulas

See all PureFormulas products
Name
PureFormulas
Street Address
11800 NW 102nd Road, Suite 2
City
Miami
State
FL
ZipCode
33178
Web Address
www.pureformulas.com
Pharmacist Counseling Corner

PF DigestChew Natural Cherry Flavor by PureFormulas: Common Questions

Does PF DigestChew Natural Cherry Flavor by PureFormulas interact with any medications?
We do not currently list a known interaction for the mapped ingredients in PF DigestChew Natural Cherry Flavor. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
PF DigestChew Natural Cherry Flavor contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product really help with digestion?
Lactase in this blend is effective for lactose intolerance. For the other enzymes—Lipase, Phytase, and the proteases—we don't have reliable evidence yet to say whether they help with digestion in supplement form. Your own response may vary.
Is it safe to take while pregnant or breastfeeding?
Lactase is likely safe in pregnancy. For Lipase, the proteases (Acid Protease and Alkaline Protease), and Phytase, there isn't enough data to know either way—talk with your doctor or pharmacist for personalized advice before using this product regularly during pregnancy or breastfeeding.
Can it cause allergic reactions?
Allergic reactions are rare but possible, especially to the proteolytic enzymes (the protein-breaking ones). Occupational exposure to airborne forms of these enzymes has triggered allergic rhinitis and asthma in some people, though that's a different scenario than taking a tablet. If you have a known enzyme allergy, check the ingredient list with your doctor first.
What's lactase for?
Lactase breaks down lactose, the natural sugar in milk and dairy. If your body doesn't make enough lactase on its own, you may have trouble digesting dairy products—taking lactase can help.
Is there anything else in this tablet besides the enzymes?
Yes. Inactive ingredients include xylitol and mannitol (sweeteners), stearic acid, silicon dioxide, and natural cherry flavor for taste. These are not active components but help make the tablet work and taste good.
Should I avoid this if I have a serious digestive condition?
Yes—check with your doctor first. People with serious digestive conditions like inflammatory bowel disease should use digestive enzyme supplements only under medical guidance, since the data on safety in those situations is limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PF DigestChew Natural Cherry Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PF DigestChew Natural Cherry Flavor label
Sources

Sources & How We Checked

PF DigestChew Natural Cherry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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