No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Phosadyl (Lecithin) Ingredients & Drug Interactions

by Douglas Laboratories

Softgel Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Phosadyl (Lecithin) is a dietary supplement by Douglas Laboratories with 3 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Phosadyl (Lecithin) by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Phosadyl is a softgel containing three phospholipid ingredients: phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol. These are naturally occurring compounds that support cell membrane function.

The product also contains soybean phosphatide complex as an inactive ingredient. Phosphatidylcholine is the ingredient with the most research behind it in this formula.

The other two phospholipids are included to round out the phospholipid profile, though we don't have detailed effectiveness data on file for them individually.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Phosphatidylcholine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Phosphatidylcholine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Ulcerative colitis — rated "Possibly Effective" (Natural Medicines).

Phosphatidylcholine is possibly effective for ulcerative colitis (a type of inflammatory bowel disease). For other conditions listed — nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety — the evidence we hold rates as insufficient to know whether it works.

If you're thinking about this supplement for one of those other uses, talk it over with your doctor. The research just isn't there yet to say it'll help.

The evidence, ingredient by ingredient Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated, but it can cause digestive upset — especially at high doses. The most common side effects from oral use are altered taste, bloating, diarrhea, nausea, vomiting, itching, and sweating.

Most people don't experience these, but if you do, they're usually mild. Choline (which phosphatidylcholine contains) is needed in pregnancy, but we don't have enough data on supplement safety beyond what you get from food.

If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting this product — they can help you figure out what makes sense for your situation.

Side effects, ingredient by ingredient Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could fully check. That doesn't mean none exist — especially since we have no interaction data for two of the three ingredients in this formula.

If you take any medications regularly, it's worth doing a quick check with your own pharmacist or doctor before you add this to your routine.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Phosadyl might be worth considering if you're dealing with ulcerative colitis, since phosphatidylcholine shows some promise there. If you're interested in it for liver health, memory, or anxiety, the evidence isn't strong enough yet to say it'll work.

Check with your doctor or pharmacist before you start, especially if you're pregnant, breastfeeding, or have a history of digestive issues.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phosadyl (Lecithin), straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539011973
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Jan 25, 2012
DSLD ID 5216
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phosadyl (Lecithin) by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
100
UPC/BARCODE
310539011973
IngredientAmount% DV
Calories12 {Calories}--
Calories from Fat12 {Calories}--
Total Fat1.4 g2%
Phosphatidylcholine420 mg--
Phosphatidylethanolamine100 mg--
Phosphatidylinositol30 mg--

Other ingredients: Soybean Phosphatide Complex

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 softgel daily or as directed by your healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

General

Formula #7926

Formulation

This product contains NO yeast, wheat gluten, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

See for yourself

Phosadyl (Lecithin) by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Phosadyl (Lecithin) by Douglas Laboratories

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Phosphatidylcholine

No known
interactions
420 mg per serving

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidylcholine monograph & interactions

Phosphatidylethanolamine

100 mg per serving

Phosphatidylinositol

30 mg per serving

Other (inactive) ingredients: Soybean Phosphatide Complex. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phosadyl (Lecithin) by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Phosadyl (Lecithin). This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Phosadyl (Lecithin), from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Phosadyl (Lecithin) by Douglas Laboratories: Common Questions

Does Phosadyl (Lecithin) by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Phosadyl (Lecithin). This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Phosadyl (Lecithin) contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylcholine and what does it do?
Phosphatidylcholine is a naturally occurring compound that helps make up cell membranes. In this product, it's the active ingredient studied for conditions like ulcerative colitis. It's generally safe at normal doses, but high amounts can cause digestive upset.
Can I take this if I'm pregnant?
Choline (which phosphatidylcholine contains) is something your body needs in pregnancy, but we don't have good safety data on supplement doses beyond food sources. Talk with your doctor before starting — they know your situation and can give you personalized advice.
Can I take this if I'm breastfeeding?
We don't have enough reliable data on phosphatidylcholine supplement use while breastfeeding. Check with your healthcare provider first — they can advise based on your specific needs.
What side effects might I get from this?
Most people tolerate it well, but some experience bloating, diarrhea, nausea, altered taste, vomiting, itching, or sweating — especially at higher doses. These are usually mild. If you're prone to digestive issues, start low and go slow.
Will this help my liver health or brain function?
We don't have strong evidence that it works for nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, or anxiety. Phosphatidylcholine does show promise for ulcerative colitis, though, so if that's your concern, it might be worth discussing with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phosadyl (Lecithin) is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phosadyl (Lecithin) label
Go deeper

The Full Monographs Behind Phosadyl (Lecithin)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Phosadyl (Lecithin)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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