No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

PhosChol Ingredients & Drug Interactions

by Nutrasal

Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

PhosChol is a dietary supplement by Nutrasal with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of PhosChol by Nutrasal

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

PhosChol has one active ingredient: phosphatidylcholine, a compound your body uses as a building block for cell membranes and nerve function. It comes from natural sources like soy and egg yolk.

The capsule also contains safflower oil, neutral spirits, and cellulose as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Liver health and nutrient support.
  • We looked for evidence on: Alcohol-related liver disease, Nonalcoholic fatty liver disease (NAFLD), Hepatitis A, Hepatitis B, Hepatitis C, Hepatic encephalopathy — and 4 related terms.
  • The strongest evidence on file: Phosphatidylcholine is rated "Possibly Effective" for Ulcerative colitis (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alcohol-related liver disease, Hepatic encephalopathy, Hepatitis C, Hepatitis A, and more.

Phosphatidylcholine is rated possibly effective for ulcerative colitis (a type of inflammatory bowel disease). For nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence isn't established well enough yet to make a reliable claim — we'd need more research to know whether it actually helps.

The evidence, ingredient by ingredient Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated at typical doses. At very high doses — especially 30 grams a day or more — it may cause digestive upset and diarrhea.

Smaller doses have been linked to bloating, diarrhea, altered taste, nausea, and vomiting in some people. When taken orally, it may also increase sweating and itching.

Choline (which your body makes from phosphatidylcholine) is needed during pregnancy, but we don't have enough safety data on supplement doses during pregnancy or breastfeeding. Talk with your doctor before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. Still, run your exact medications through the search tool on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have ulcerative colitis, this supplement has some research behind it and might be worth discussing with your doctor. For other uses, the evidence isn't there yet.

Because it's generally well tolerated, most people won't run into problems — but start at the lower end of the dose if you have a sensitive stomach. Always check with your pharmacist before adding it to your routine, especially if you're pregnant, nursing, or take other supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PhosChol, straight from the product label.

Brand Nutrasal
Barcode (UPC) 602573159262
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 321812
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PhosChol by Nutrasal, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
602573159262
IngredientAmount% DV
Calories15 Calorie(s)--
Calories from Fat15 Calorie(s)--
Total Fat1.5 Gram(s)2%
Saturated Fat0 Gram(s)--
Phosphatidylcholine1200 mg--

Other ingredients: Safflower Oil, neutral Spirits, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Each serving provides: 1200 mg of pharmaceutical grade polyenylphosphatidylcholine (PPC).

100% polyenylphosphatidylcholine PPC Polyenylphosphatidylcholine

Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, take 2 capsules once or twice daily, or as directed by your health care practitioner.

Storage

Storage: Keep tightly closed in a cool dry place, out of the reach of children.

Precautions

Storage: Keep tightly closed in a cool dry place, out of the reach of children.

Do not take if tamper resistant seal is broken or missing. This product is pharmaceutical grade and intended for professional use.

Formulation

This product is pharmaceutical grade and intended for professional use. It is manufactured under strict quality controls to ensure purity, potency, and reliability.

Pharmaceutical grade

Contains no: Wheat, gluten, corn, soy protein, yeast, dairy products, artificial colors, sweeteners, or preservatives.

Seals/Symbols

Manufactured in the USA cGMP Compliant

Brand IP Statement(s)

Nutrasal Advanced Lipid Science

FDA Statement of Identity

Dietary Supplement

See for yourself

PhosChol by Nutrasal label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PhosChol by Nutrasal

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Phosphatidylcholine

No known
interactions
1200 mg per serving Form: Polyenylphosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidylcholine monograph & interactions

Other (inactive) ingredients: Safflower Oil, Neutral Spirits, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

PhosChol by Nutrasal Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in PhosChol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for PhosChol, from the product label.

Nutrasal

See all Nutrasal products
Name
Nutrasal, Inc.
City
Scottsdale
State
AZ
Phone Number
800.777.1886
Web Address
nutrasal.com
Pharmacist Counseling Corner

PhosChol by Nutrasal: Common Questions

Does PhosChol by Nutrasal interact with any medications?
We do not currently list a known interaction for the mapped ingredients in PhosChol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
PhosChol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylcholine and why is it in this product?
Phosphatidylcholine is a natural compound your body uses to build and repair cell membranes and support nerve function. It's found in foods like eggs and soy, and in supplements like this one, it's meant to support liver and digestive health.
Does this actually work for ulcerative colitis?
There's some research suggesting it may help, so we rate it possibly effective. That's not a guarantee, and you'll want to talk with your gastroenterologist about whether it makes sense for your situation alongside your regular treatment.
What side effects should I watch for?
Most people tolerate it well. The most common issues are bloating, diarrhea, nausea, and altered taste. If you take very high doses — more than 30 grams a day — digestive upset becomes more likely. Start with a smaller dose if you have a sensitive stomach.
Can I take this while pregnant or breastfeeding?
We don't have enough data on supplement doses during pregnancy or breastfeeding to say it's safe. Choline itself is needed in pregnancy, but talk with your doctor or midwife before starting a supplement version — they can give you personalized advice based on your situation.
Is this the same as choline?
No, they're related but different. Phosphatidylcholine is a compound that contains choline, and your body can break it down and use the choline it needs. They're not interchangeable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PhosChol is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PhosChol label
Sources

Sources & How We Checked

PhosChol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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