No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Phosphatidyl Choline Ingredients & Drug Interactions

by NutriCology

Phosphatidyl Choline label
See full label image
Softgel Capsule Category: Fat/fatty Acid
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Phosphatidyl Choline against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Phosphatidyl Choline is a dietary supplement by NutriCology with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Phosphatidyl Choline by NutriCology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: phosphatidylcholine, a type of phospholipid (a fat-like substance) found naturally in cell membranes throughout the body. The softgel capsule also includes gelatin, glycerin, purified water, polyglycitol syrup, and soybean oil as inactive ingredients that hold everything together.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: memory, brain health, liver and cell membranes.
  • We looked for evidence on: Memory, Dementia, Alzheimer disease, Nonalcoholic fatty liver disease (NAFLD), Alcohol-related liver disease, Hepatitis A — and 4 related terms.
  • The closest evidence on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alcohol-related liver disease (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Hepatitis C, Hepatitis A, Hepatitis B, and more.

Phosphatidylcholine is rated possibly effective for ulcerative colitis, an inflammatory bowel condition. For nonalcoholic fatty liver disease (NAFLD), alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence we hold is insufficient — meaning there isn't enough reliable research yet to say whether it works for these conditions.

Talk with your doctor about whether this supplement fits your particular situation.

The evidence, ingredient by ingredient Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated when taken by mouth. At typical doses, side effects are uncommon, but high doses — especially 30 grams per day or more — may cause digestive upset, bloating, diarrhea, nausea, or vomiting.

Some people also report altered taste, itching, and sweating. Choline (which phosphatidylcholine provides) is needed during pregnancy, but the safety of supplements beyond what you get from food hasn't been well studied in pregnancy — check with your doctor.

There isn't enough data on supplement use while breastfeeding either; speak with your healthcare provider first.

Side effects, ingredient by ingredient Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for this product in our data. You're free to check your specific medications using the search tool on this page, but there are no known drug-supplement interactions to flag ahead of time.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is a reasonable option if you're exploring support for ulcerative colitis or if your doctor has suggested phosphatidylcholine for another reason — it's well tolerated at typical doses and has no known medication interactions we've documented. If you're pregnant, breastfeeding, or considering it for a condition beyond ulcerative colitis, talk it through with your doctor or pharmacist first to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phosphatidyl Choline, straight from the product label.

Brand NutriCology
Barcode (UPC) 713947522404
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235338
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phosphatidyl Choline by NutriCology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Softgel(s)
Maximum serving Sizes:
4 Softgel(s)
Servings per container
25
UPC/BARCODE
713947522404
IngredientAmount% DV
Phosphatidylcholine1.54 Gram(s)--

Other ingredients: Gelatin, Glycerin, purified Water, Polyglycitol Syrup, Soybean Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Phosphatidylcholine, a primary component of lecithin, may be converted in the brain into the neurotransmitter acetylcholine.

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 to 4 softgels two or three times daily with meals, or as directed by a healthcare practitioner.

Formulation

Variations in product color may occur.

For Brain, Liver, and Cell Membranes

Storage

Keep in a cool, dry place, tightly capped.

Precautions

Contains: Soy.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

NutriCology Innovative Nutrition

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Phosphatidyl Choline by NutriCology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Phosphatidyl Choline label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Phosphatidyl Choline by NutriCology

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Softgel(s) Dosage formSoftgel Capsule Servings per container25 Amounts shown are per serving.

Phosphatidylcholine

No known
interactions
1.54 Gram(s) per serving Form: Soy Lecithin

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidylcholine monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Purified Water, Polyglycitol Syrup, Soybean Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phosphatidyl Choline by NutriCology Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Phosphatidyl Choline. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Phosphatidyl Choline, from the product label.

NutriCology

See all NutriCology products
Name
NutriCology
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.nutricology.com
Pharmacist Counseling Corner

Phosphatidyl Choline by NutriCology: Common Questions

Does Phosphatidyl Choline by NutriCology interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Phosphatidyl Choline. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Phosphatidyl Choline contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylcholine?
It's a phospholipid — a fat-like compound that's a natural part of your cell membranes. You get small amounts in foods, and this supplement provides a concentrated dose. Your body uses it to maintain cell structure and function.
Does this help with ulcerative colitis?
It's rated possibly effective for ulcerative colitis, meaning there's some research suggesting it may help, but the evidence isn't conclusive yet. If you're managing ulcerative colitis, discuss it with your doctor to see if this fits your treatment plan.
Can it cause digestive side effects?
At normal doses, it's usually well tolerated. But high doses — especially 30 grams a day or more — may trigger bloating, diarrhea, nausea, or vomiting. If you notice stomach upset, you might try a lower dose or check with your pharmacist.
Is it safe to take while pregnant?
Choline is actually needed in pregnancy, but the safety of taking supplements beyond what you get from food hasn't been well studied. Check with your doctor before starting it during pregnancy to make sure it's the right choice for you.
Can I take it while breastfeeding?
There isn't enough reliable data on supplement use while breastfeeding. Talk with your healthcare provider first to get personalized advice for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phosphatidyl Choline is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phosphatidyl Choline label
Go deeper

The Full Monographs Behind Phosphatidyl Choline’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph →
Sources

Sources & How We Checked

Phosphatidyl Choline's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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