No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Phosphine III Ingredients & Drug Interactions

by DC

Softgel Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Phosphine III is a dietary supplement by DC with 2 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Phosphine III by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Phosphine III contains 2 active ingredients: phosphatidyl choline and soy lecithin. Phosphatidyl choline is a fat-soluble compound that supports cell membranes and may help with certain digestive and liver conditions.

Soy lecithin is a phospholipid derived from soy that functions similarly in the body. The softgel capsule also contains gelatin and vegetable glycerin as inactive ingredients to deliver the actives.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Memory, brain, and liver support.
  • We looked for evidence on: Memory, Age-related cognitive decline, Dementia, Alzheimer disease, Nonalcoholic fatty liver disease (NAFLD), Alcohol-related liver disease — and 4 related terms.
  • The strongest evidence on file: Phosphatidylcholine is rated "Possibly Effective" for Ulcerative colitis (Natural Medicines).
  • Also on file: Lecithin is rated "Likely Ineffective" for Alzheimer disease.
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alcohol-related liver disease, Alzheimer disease, Hepatic encephalopathy, Memory, and more.

The evidence for phosphatidyl choline is mixed. It's possibly effective for ulcerative colitis, but evidence is insufficient to rate it for nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer's disease, or anxiety.

Soy lecithin is likely ineffective for Alzheimer's disease and has insufficient evidence for age-related cognitive decline, liver support during IV nutrition, and anxiety. The data we hold doesn't establish strong effectiveness for either ingredient across most of the conditions people consider them for.

The evidence, ingredient by ingredient Phosphatidylcholine Lecithin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidyl choline is generally well tolerated in food and supplement amounts, though high doses may cause digestive upset — bloating, diarrhea, nausea, altered taste, vomiting, and sweating have been reported. Soy lecithin is also well tolerated orally and may cause abdominal pain, diarrhea, fullness, or nausea; if you have egg or soy allergies, it can trigger allergic skin reactions.

For pregnancy, choline is needed, but supplement safety beyond food amounts hasn't been well studied — check with your doctor. Data on breastfeeding use is limited; talk with your healthcare provider first.

Soy lecithin is likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Phosphatidylcholine Lecithin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. That doesn't mean none exist — it means we haven't found them documented.

Before you start, confirm with your own pharmacist or doctor that it's okay alongside any prescriptions you take.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Phosphine III may be worth considering if you're exploring support for ulcerative colitis or liver health, though evidence is strongest only for the first. If you're pregnant, breastfeeding, allergic to soy or eggs, or concerned about digestive upset, talk it over with your doctor or pharmacist before starting.

They can weigh the evidence and your personal health picture to help you decide.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phosphine III, straight from the product label.

Brand DC
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 245527
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phosphine III by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Calories10 Calorie(s)--
Calories from Fat10 Calorie(s)--
Total Fat1 Gram(s)1%
Phosphatidyl Choline420 mg--
Soy Lecithin1200 mg--

Other ingredients: Gelatin, Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 softgel twice daily.

Formula

Soybean phosphatide complex containing a minimum 35% (420 mg.) of important phosphatidyl choline which is equivalent to 65 mg. of natural choline, enclosed with gelatin to ensure freshness and potency. Phosphine III provides 3 times more choline than a regular 1200 mg. lecithin softgel.

Natural phosphatidyl choline from soybean oil

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Contains soy ingredients.

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Gluten free

Choline is important for normal cellular membrane composition and repair, normal brain, cardiovascular and liver function.

Made in USA

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

See for yourself

Phosphine III by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Phosphine III by DC

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Phosphatidyl Choline

No known
interactions
420 mg per serving

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidyl Choline monograph & interactions

Soy Lecithin

No known
interactions
1200 mg per serving

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Soy Lecithin monograph & interactions

Other (inactive) ingredients: Gelatin, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phosphine III by DC Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Phosphine III. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Phosphine III, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Phosphine III by DC: Common Questions

Does Phosphine III by DC interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Phosphine III. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Phosphine III contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's phosphatidyl choline, and what does it do?
It's a fat-soluble compound that's a building block of cell membranes throughout your body. It may support digestion and liver function, though evidence is strongest for ulcerative colitis.
Can I take this if I'm pregnant or breastfeeding?
Choline itself is needed in pregnancy, but we don't have enough data on supplement safety beyond what's in food — check with your doctor. Soy lecithin is likely safe while pregnant or nursing, but phosphatidyl choline data is limited; talk with your healthcare provider for personalized advice.
What side effects might I notice?
The most common are digestive: bloating, diarrhea, nausea, and altered taste. Sweating and itching have also been reported. These are usually mild, but high doses raise the risk of more pronounced upset.
Is this safe if I have a soy allergy?
The product contains soy lecithin, which can trigger allergic skin reactions in people with soy allergies. Skip it and choose an alternative, or talk with your doctor first.
Will this help with brain fog or memory?
Soy lecithin is likely ineffective for Alzheimer's disease, and evidence is insufficient for age-related cognitive decline. Phosphatidyl choline doesn't have established effectiveness for these purposes either.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phosphine III is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phosphine III label
Sources

Sources & How We Checked

Phosphine III's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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