Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Plant Enzymes Starter Ingredients & Drug Interactions

by Enriching Gifts

Plant Enzymes Starter label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Plant Enzymes Starter against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Plant Enzymes Starter is a dietary supplement by Enriching Gifts with 4 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.Based on those ingredients, 141 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Plant Enzymes Starter by Enriching Gifts

Ask about any prescription or over-the-counter medication and we check it for interactions with Plant Enzymes Starter by Enriching Gifts — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Plant Enzymes Starter by Enriching Gifts

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “GR8CF-77 Enzyme & Mineral Blend” is a proprietary blend — the label gives one combined amount (300 mg) without saying how much of each component you get.
  • “GR8 Mineral Blend” is a proprietary blend — the label gives one combined amount (15 mg) without saying how much of each component you get.

Plant Enzymes Starter contains 9 active enzyme ingredients designed to support digestion. Bromelain is a protein-digesting enzyme from pineapple.

Protease and lipase are enzymes that break down proteins and fats respectively in food. Lactase breaks down the milk sugar lactose.

The product also contains amylase, cellulase, invertase, diastase, and alpha-galactosidase—all enzymes that help break down different carbohydrates and other food components. The inactive ingredients listed include hypromellose (a capsule material), microcrystalline cellulose, magnesium stearate, rice extract, rice husk, gum arabic, and sunflower oil.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“Digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).

Lactase, one of the enzymes in this product, is rated effective for lactose intolerance—the inability to digest milk sugar. For the other active enzymes and the conditions they're sometimes used for—such as hay fever, burns, diabetes, or various digestive issues—the evidence in our data is rated insufficient to establish whether they work.

That doesn't mean they don't; it means reliable research backing their effectiveness for those uses hasn't been established in the sources we hold.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bromelain is generally well tolerated for short-term use, though long-term safety data is limited. It may cause diarrhea, flatulence, stomach upset, or headache when taken by mouth.

Rarely, people can have allergic reactions to bromelain, especially if they inhale it (which can trigger asthma or throat irritation); oral allergic reactions are possible but uncommon. Protease and lipase are also generally well tolerated, though protease may rarely trigger allergic reactions.

For pregnancy, the data advises against bromelain—there isn't enough safety information. Lactase is rated likely safe in pregnancy.

For protease and lipase, there isn't enough data during pregnancy or breastfeeding to know either way; talk with your doctor before using during these times. Bromelain should be avoided while breastfeeding because safety data is unavailable.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 4 matched ingredients can interact with medications — Bromelain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check if you take blood thinners or antiplatelet drugs (like warfarin or aspirin)—bromelain may increase bleeding risk. Also mention tetracycline antibiotics to your doctor or pharmacist, since bromelain might affect how your body absorbs them.

If you're on any prescription medication, run it through the search tool on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help if you have trouble digesting lactose or simply want enzyme support for general digestion. If you take blood thinners, antiplatelet medications, or tetracycline antibiotics, check your specific drugs with the tool on this page before starting, and confirm the go-ahead with your own doctor or pharmacist.

Pregnant or breastfeeding individuals should also talk with their healthcare provider first, especially regarding bromelain.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Plant Enzymes Starter, straight from the product label.

Brand Enriching Gifts
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 276547
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Plant Enzymes Starter by Enriching Gifts, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
IngredientAmount% DV
Amylase0 NP--
Bromelain0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Diastase0 NP--
Alpha-Galactosidase0 NP--
GR8CF-77 Enzyme & Mineral Blend300 mg--
GR8 Mineral Blend15 mg--

Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Magnesium Stearate, Rice extract, Rice Husk, Gum Arabic, Sunflower Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules per serving before meals.

Precautions

Caution: Not recommended for children 6 years or younger or if pregnant or lactating

Caution: Not recommended for children 6 years or younger or if pregnant or lactating

Do not use if safety seal is broken

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Digestive Support

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Plant Enzymes Starter by Enriching Gifts label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Plant Enzymes Starter label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Plant Enzymes Starter by Enriching Gifts

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

GR8CF-77 Enzyme & Mineral Blend

300 mg per serving
  • › Amylase
  • › Protease
  • › Cellulase
  • › GR8 Mineral Blend

Other (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Magnesium Stearate, Rice extract, Rice Husk, Gum Arabic, Sunflower Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Plant Enzymes Starter by Enriching Gifts Drug Interactions

Want to check YOUR meds against Plant Enzymes Starter?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
141Drugs
122 Moderate 19 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Plant Enzymes Starter interact with 141 drugs. Click any drug to see the details.

0 of the 4 ingredients in Plant Enzymes Starter interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Plant Enzymes Starter with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Plant Enzymes Starter, from the product label.

Enriching Gifts

See all Enriching Gifts products
Name
Enriching Gifts Intl. Inc
Street Address
915 S. Lake Ave
City
Miles City
State
MT
ZipCode
59301
Phone Number
1-406-232-4414
Web Address
www.enrichinggifts.com
Pharmacist Counseling Corner

Plant Enzymes Starter by Enriching Gifts: Common Questions

Does Plant Enzymes Starter by Enriching Gifts interact with any medications?
Yes. Based on its ingredients, Plant Enzymes Starter has a known interaction with 141 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Plant Enzymes Starter contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with gas and bloating?
These enzymes are meant to help break down different foods—proteins, fats, and carbohydrates—which is their role in digestion. The evidence for whether they actually reduce gas or bloating isn't established in our data, so results vary by person. If you try it, give it a fair test and see how you feel.
Can I take this if I'm on a blood thinner?
Bromelain in this product may increase bleeding risk if you're on a blood thinner like warfarin. Don't start this supplement without checking with your doctor or pharmacist first—they know your full medication list and can advise whether it's safe for you.
What are the side effects?
Bromelain may cause diarrhea, gas, stomach upset, or headache. Rarely, allergic reactions can occur—ranging from mild rash to asthma if inhaled. Protease and lipase are generally well tolerated, though digestive upset is possible. Stop and call your doctor if you have signs of an allergic reaction.
Is it safe to take while pregnant?
Bromelain should be avoided during pregnancy because there isn't enough safety data. Lactase is rated likely safe. Protease and lipase don't have enough data either way—talk with your doctor before using any of this product while pregnant.
Can I take this while breastfeeding?
Bromelain should be avoided while breastfeeding. Lactase and the other enzymes don't have enough safety information during breastfeeding. Check with your doctor or pharmacist before starting to be sure.
What does each enzyme do?
Bromelain and protease break down proteins; lipase breaks down fats; lactase breaks down milk sugar; amylase, diastase, invertase, and cellulase break down different types of carbohydrates and fiber. Together they're meant to help your digestive system process a wide range of foods.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Plant Enzymes Starter is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Plant Enzymes Starter label
Go deeper

The Full Monographs Behind Plant Enzymes Starter’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph →
Sources

Sources & How We Checked

Plant Enzymes Starter's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bromelain 19 references
  1. Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
  2. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
  3. Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
  4. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  5. Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
  6. Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
  7. Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
  8. Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
  9. Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
  10. Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
  11. Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
  12. Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
  13. Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
  14. Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
  15. Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
  16. Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
  17. Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
  18. Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
  19. Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed

See these in context on the Bromelain monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team