Precision D-Mannose 500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Precision D-Mannose 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Precision D-Mannose 500 mg is a dietary supplement by Swiss BioEnergetics with 1 active ingredient. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Precision D-Mannose 500 mg by Swiss BioEnergetics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: D-mannose, a simple sugar. D-mannose is used to support urinary tract health and is also used medically in rare genetic conditions affecting how the body processes certain proteins.
The capsule is made with hydroxypropyl methylcellulose (a plant-based capsule material) and magnesium stearate (a binder). No fillers or artificial additives are listed.
Does it work?
Strong evidence
The evidence behind D-mannose is mixed. For carbohydrate-deficient glycoprotein syndrome type 1b — a rare genetic disorder — it's likely effective.
For urinary tract infections (UTIs), however, the evidence suggests it's possibly ineffective, meaning it hasn't shown reliable benefit in clinical trials. If you're considering this for UTI prevention or treatment, talk with your doctor about whether it's right for you or if other approaches make more sense.
How safe is it?
Well-documented data
D-mannose is generally well tolerated in the short term, but long-term safety data from high-quality studies are limited. The most common side effects are bloating, diarrhea, and nausea — especially at higher doses.
Children and adults taking it have reported loose stools and abdominal bloating; diarrhea is more likely when a single dose exceeds about 200 mg per kilogram of body weight. Safety in pregnancy isn't well studied, so the data advises caution.
There isn't enough reliable information about safety while breastfeeding either. Talk with your doctor or pharmacist before taking this if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for the D-mannose in this product. That said, always run your complete medication list through the checker on this page, and confirm with your own pharmacist or doctor before taking this supplement alongside any prescription or over-the-counter drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Precision D-Mannose may be worth considering if your doctor recommends it for carbohydrate-deficient glycoprotein syndrome type 1b, though it's not likely to help with UTIs based on current evidence. Watch for bloating, diarrhea, or nausea, especially if you're taking larger doses.
If you're pregnant, breastfeeding, or taking any medications, check with your pharmacist or doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Precision D-Mannose 500 mg, straight from the product label.
| Brand | Swiss BioEnergetics |
|---|---|
| Barcode (UPC) | 5060361463451 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 284365 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Precision D-Mannose 500 mg by Swiss BioEnergetics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| D-Mannose | 500 mg | -- |
Other ingredients: D-Mannose, Hydroxypropyl Methylcellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
Manufactured in the UK GMP Consistent Quality
FDA Statement of Identity
Food Supplement
Suggested/Recommended/Usage/Directions
DIRECTIONS: Adults, take 3 capsules 1 to 3 times daily with water or unsweetened juice, such as cranberry. Do not exceed recommended daily dose.
Precautions
ALLERGY ADIVCE: Although rigorous precautions are taken to prevent any cross-contamination, this product is manufactured in a facility that also handles allergy-based materials such as nuts, seeds, milk, egg, cereals, soya, mustard, celery, fish, crustaceans and sulphites.
CAUTIONS: Always consult your health practitioner before taking nutritional supplements, especially if you are taking medication or are under medical supervision.
You should not take supplements as a substitute for a varied balanced diet or healthy lifestyle.
Store in a cool dry place, out of reach of children.
Storage
Store in a cool dry place, out of reach of children.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Precision D-Mannose 500 mg by Swiss BioEnergetics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Precision D-Mannose 500 mg by Swiss BioEnergetics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
D-Mannose
No knowninteractions
D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...
D-Mannose monograph & interactionsOther (inactive) ingredients: D-Mannose, Hydroxypropyl Methylcellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Precision D-Mannose 500 mg by Swiss BioEnergetics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Precision D-Mannose 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Precision D-Mannose 500 mg, from the product label.
Swiss BioEnergetics
See all Swiss BioEnergetics products- Name
- Countercom Ltd
- Street Address
- 310 Harrow Road
- City
- Middlesex
- State
- HA9 6LL
- Web Address
- www.swissbioenergetics.com
Precision D-Mannose 500 mg by Swiss BioEnergetics: Common Questions
Does Precision D-Mannose 500 mg by Swiss BioEnergetics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will D-mannose help prevent or treat a urinary tract infection?
What are the most common side effects?
Is D-mannose safe to take long-term?
Can I take this while breastfeeding?
Can I take this while pregnant?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Precision D-Mannose 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Precision D-Mannose 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Precision D-Mannose 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
D-mannose 6 references
- Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
- Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
- de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
- Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
- . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
- Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC