Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Primal Queen Ingredients & Drug Interactions

by Primal Queen

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Primal Queen is a dietary supplement by Primal Queen with 5 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Bovine Liver, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Primal Queen by Primal Queen

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Primal Queen Proprietary Blend” is a proprietary blend — the label gives one combined amount (337.50 mg) without saying how much of each component you get.

Primal Queen is a 5-ingredient formula of bovine organ powders delivered in capsule form. The main active ingredients are powdered extracts from cow uterus, ovary, liver, kidney, and heart, supplied as a proprietary blend.

The capsules themselves contain gelatin and a flow agent called Nu-Flow.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness evidence on file for Primal Queen or its individual organ powders as a product. Liver extract specifically has been studied for chronic fatigue syndrome and hepatitis C, but the data shows it's possibly ineffective for fatigue and there's insufficient evidence for hepatitis C.

The other organ powders — uterus, ovary, kidney, and heart — haven't been rated in our data. If you're considering this for a specific health goal, it's worth talking with us about what the research actually shows.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported for liver extract in the medical literature, but a full safety review hasn't been done. There's a concern about possible contamination: liver products come from slaughterhouse animals that may be sick or diseased, and liver extracted from cows in countries where bovine spongiform encephalitis (BSE, also called mad cow disease) has been found could theoretically carry contaminated tissue.

Great Britain, France, The Netherlands, Portugal, Luxembourg, Ireland, Switzerland, Oman, and Belgium have reported BSE. So far, no cases of BSE have been traced to liver extract products in humans.

Liver extract can deliver very high amounts of vitamin A, which may harm a developing baby — avoid it in pregnancy unless your doctor advises otherwise. Because safety hasn't been well studied overall, check with your doctor before using, especially if you're pregnant, nursing, or have health conditions.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with us if you take warfarin (Coumadin) or blood thinners — the liver extract could theoretically weaken their effect. Also flag if you take iron supplements or iron medications.

No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Primal Queen is an organ-powder blend with minimal interaction data and no proven effectiveness in our records. If you take warfarin or iron supplements, or have any other prescriptions, check them against this product first.

Talk to your pharmacist about whether this makes sense for your health goals and any sourcing or contamination concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Primal Queen, straight from the product label.

Brand Primal Queen
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 333276
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Primal Queen by Primal Queen, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Primal Queen Proprietary Blend337.5 mg--
Bovine Uterus, Powder0 NP--
Bovine Ovary, Powder0 NP--
Bovine Liver, Powder0 NP--
Bovine Kidney, Powder0 NP--
Bovine Heart, Powder0 NP--

Other ingredients: Nu-Flow, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Viral on Tik Tok

Formula

Nourish your body like a queen with 100% grass fed & pasture raised beef organs

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: -Take 1 Primal Queen capsule with every meal. 2 daily.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Primal Queen by Primal Queen label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Primal Queen by Primal Queen

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Primal Queen Proprietary Blend

337.5 mg per serving
  • › Bovine Uterus, Powder
  • › Bovine Ovary, Powder
  • Bovine Liver, Powder
  • › Bovine Kidney, Powder
  • › Bovine Heart, Powder

Other (inactive) ingredients: Nu-Flow, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Primal Queen by Primal Queen Drug Interactions

Want to check YOUR meds against Primal Queen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Primal Queen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bovine Liver, Powder2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Primal Queen, from the product label.

Primal Queen

See all Primal Queen products
Name
Primal Queen
Pharmacist Counseling Corner

Primal Queen by Primal Queen: Common Questions

Does Primal Queen by Primal Queen interact with any medications?
Yes. Based on its ingredients, Primal Queen has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Primal Queen contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe in pregnancy?
Liver extract can contain very high vitamin A, which may harm a developing baby. The safety notes advise against it in pregnancy unless your doctor specifically says it's okay. For the other organ powders — uterus, ovary, kidney, and heart — we don't have pregnancy safety data on file. Talk to your doctor or pharmacist before taking any of these during pregnancy.
Can I take this while breastfeeding?
We don't have lactation safety data on file for these organ powders. Because liver extract can carry high levels of some nutrients and safety hasn't been well studied overall, check with your doctor or pharmacist before using while breastfeeding.
Will this help with fatigue or energy?
Liver extract has been studied for chronic fatigue syndrome and found to be possibly ineffective. We don't have effectiveness data for the other organ powders in this formula. If boosting energy is your goal, we'd recommend talking about what the evidence actually supports.
Where does the liver powder come from, and is it safe?
The safety notes mention concern about possible contamination from slaughterhouse sources and potential BSE (mad cow disease) risk if the cows came from affected countries. No BSE transfer to humans from liver extract has been reported so far, but this is something to ask the manufacturer about — specifically, which countries the liver is sourced from.
What is bovine organ powder, and why would I take it?
It's powdered tissue from cow organs — in this case, uterus, ovary, liver, kidney, and heart. The idea behind 'organ support' supplements is that nutrients from these tissues may support your own organ function, but we don't have strong evidence that these powders work for any specific health purpose.
Can I take this with my multivitamin?
If your multivitamin contains iron, you should be careful — the liver powder in this product can also contain heme iron, and combining them might raise your total iron intake. Check the iron content of both and talk with us before adding this on top of a multi.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Primal Queen label
Sources

Sources & How We Checked

Primal Queen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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