Pro-Rite Ingredients & Drug Interactions
by Carlson
What is this page for?
First and foremost: checking Pro-Rite against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pro-Rite is a dietary supplement by Carlson with 2 active ingredients. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pro-Rite by Carlson
Ask about any prescription or over-the-counter medication and we check it for interactions with Pro-Rite by Carlson — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pro-Rite by Carlson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Pro-Rite contains two amino acids: L-Proline and L-Lysine. These are building blocks your body uses in collagen, connective tissue, and immune function.
The product comes in a hypromellose capsule.
Does it work?
Not established
L-Lysine is possibly effective for cold sores (herpes labialis). The evidence for both ingredients in wound healing, bone health, osteoporosis, fractures, and child growth is insufficient — we don't yet have reliable data to say whether they work for those purposes.
How safe is it?
Well-documented data
Both amino acids are generally well tolerated at typical doses. At high amounts, L-lysine may cause stomach upset, abdominal pain, or diarrhea.
There is one rare case report linking long-term oral L-lysine to kidney problems, though this is not common. Supplement safety in pregnancy and breastfeeding hasn't been well studied for either ingredient.
If you're pregnant, planning to be, or breastfeeding, talk with your doctor or pharmacist before starting Pro-Rite.
Meds to double-check
Minor interactions only
If you take 5-HT4 agonists (drugs for certain digestive conditions), L-lysine in this product may reduce their effectiveness. Check your exact medication with your doctor or pharmacist before taking Pro-Rite.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.
Pro-Rite may be worth considering if you're interested in amino acid supplementation for collagen support or if you use L-lysine for cold sores. If you take any prescription medications—especially digestive drugs—check your exact medication list with the interaction tool on this page before you start.
Talk with your doctor or pharmacist about whether Pro-Rite fits your health plan.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pro-Rite, straight from the product label.
| Brand | Carlson |
|---|---|
| Barcode (UPC) | 088395687303 |
| Net contents | 200 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 19, 2022 |
| DSLD ID | 266385 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pro-Rite by Carlson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Proline | 500 mg | -- |
| L-Lysine | 500 mg | -- |
Other ingredients: Hypromellose capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Free-form L-Proline & L-Lysine
Pro-Rite combines free-form L-proline and L-lysine, essential components for healthy collagen formation. Collagen is a structural component that helps form the connective tissues for healthy ligaments, blood vessels, and bones.
FDA Statement of Identity
Dietary Supplement
Formulation
Cardiovascular health Joint support Collagen formation
Natural color variation may occur.
Gluten-free No artificial preservatives
Potency & quality guaranteed An FDA regulated facility
General Statements
100 Servings
Suggested/Recommended/Usage/Directions
Directions: Adults: take two capsules daily at mealtime.
Precautions
Warning: Consult a physician before taking if pregnant or lactating, taking medication or have a medical condition.
Keep out of reach of children.
Storage
Store in a cool, dry place after opening.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Carlson Providing the highest quality nutritional supplements since 1965
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pro-Rite by Carlson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pro-Rite by Carlson
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Proline
No knowninteractions
Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...
L-Proline monograph & interactionsL-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOther (inactive) ingredients: Hypromellose capsule. These complete the product’s ingredient list but are not active constituents.
Pro-Rite by Carlson Drug Interactions
HelloPharmacist Interaction Report
Pro-Rite by Carlson contains L-lysine, which has a documented Minor interaction with 5-HT4 agonists (a class of drugs used for certain gastrointestinal conditions).
L-lysine may reduce how well these medications work by acting as a partial antagonist to the serotonin receptor 4 that these drugs target.
Read the full breakdown — every affected drug type, severity by severity
L-Proline, the other active ingredient, has no known interactions documented in our data.
Altogether, these interactions span 1 individual medication. If you take a 5-HT4 agonist or any other prescription medication, use the interaction checker below with your exact drug names before you start Pro-Rite.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Pro-Rite?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pro-Rite interact with 1 drug. Click any drug to see the details.
1 of the 2 ingredients in Pro-Rite interact with drugs. Each result below shows which ingredient is responsible. L-Lysine
TegaserodZelnorm
How Tegaserod interacts with Pro-Rite — through 1 ingredient. Tap an ingredient for the detail:
L-lysine5-ht4 Agonists Minor
Interaction Summary
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Read the full L-lysine + Tegaserod interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pro-Rite with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for Pro-Rite, from the product label.
Carlson
See all Carlson products- Name
- Carlson Div. of J.R. Carlson Laboratories, Inc.
- City
- Arlington Heights
- State
- IL
- ZipCode
- 60004
- Phone Number
- 888-234-5656
- Web Address
- www.carlsonlabs.com
Pro-Rite by Carlson: Common Questions
Does Pro-Rite by Carlson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-lysine really help with cold sores?
What side effects might I get from Pro-Rite?
Can I take Pro-Rite while I'm pregnant or breastfeeding?
What is L-Proline for?
How much L-lysine does Pro-Rite have per dose?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pro-Rite is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pro-Rite’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proline
Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of collagen, but strong human evidence that...
Read the full Proline monograph → Herb & supplement monographLysine
Interacts with 1 drugLysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...
Read the full Lysine monograph →Sources & How We Checked
Pro-Rite's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proline 4 references
- Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
- Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
- Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
- Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC