ProtoZymes Ingredients & Drug Interactions
What is this page for?
First and foremost: checking ProtoZymes against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ProtoZymes is a dietary supplement by Protocol For Life Balance with 8 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of ProtoZymes by Protocol For Life Balance
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
ProtoZymes is a blend of 8 digestive enzymes. The checked ingredients include Protease (breaks down protein), Lipase (breaks down fat), and Lactase (breaks down the milk sugar lactose).
You'll also find Amylase, Glucoamylase, Invertase, and Diastase — all carbohydrate-digesting enzymes — plus a proprietary enzyme blend called BioCore Vegetarian Enzymes. The product also contains inactive ingredients like fructose, rice dextrin, and natural flavors to flavor and bind the tablet.
Does it work?
Strong evidence
The evidence on these enzymes is mixed. Lactase is effective for lactose intolerance — that one has solid support.
For the others, the data we hold shows insufficient evidence to rate how well they work for digestive issues like inflammatory bowel disease or upset stomach (dyspepsia). That doesn't mean they don't work; it means the clinical evidence isn't established enough in the data we have.
How safe is it?
Well-documented data
The enzymes in this product are generally well tolerated in most adults, though some people report mild digestive upset or allergic reactions. Protease and other enzymes can occasionally trigger allergies — rarely, occupational exposure to airborne proteolytic enzymes has caused allergic rhinitis (nasal inflammation) or asthma in workers.
If you have serious digestive conditions, check with your doctor before using. During pregnancy, safety data is limited for most of these enzymes; Lactase is rated likely safe, but talk with your doctor before regular use of this product while pregnant or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, several ingredients — Amylase, Glucoamylase, Invertase, and Diastase — we were unable to check.
If you take any blood thinners, diabetes medications, or drugs that affect how your stomach and intestines work, mention this product to your doctor or pharmacist before starting it.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're looking for general digestive enzyme support and don't have a serious gut condition, this product is generally well tolerated. People with inflammatory bowel disease or other serious digestive issues should clear it with their doctor first.
Check your medications using the tool on this page or ask your pharmacist before you start — even though no interactions are documented in our data, you deserve personalized advice about how it fits with your health.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ProtoZymes, straight from the product label.
| Brand | Protocol For Life Balance |
|---|---|
| Barcode (UPC) | 707359129573 |
| Net contents | 90 Chewable(s) |
| Market status | On market |
| Date entered into DSLD | Jan 25, 2017 |
| DSLD ID | 69370 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ProtoZymes by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Added Sugars | 1 Gram(s) | 2% |
| Total Sugars | 1 Gram(s) | -- |
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Protease | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Diastase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| BioCore Vegetarian Enzymes | 144 mg | -- |
Other ingredients: Fructose, Natural Flavors, Rice Dextrin, Citric Acid, Magnesium Stearate, Beet powder
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
SUGGESTED USAGE: Adults: Chew 2 tablets with or before each meal. Children (ages 4 & up): Chew 1 tablet with or before each meal. Or use as directed by your healthcare practitioner.
Storage
Keep lid tightly sealed.
Formula
How It Works: ProtoZymes is a broad spectrum digestive enzyme formulation designed to support optimal breakdown and absorption of proteins, fats, and carbohydrates, including lactose, to ensure maximum nutritional value for you and your children.* ProtoZymes has been designed especially for children, but it can also be used by adults to enhance bioaccessibility of nutrients consumed in foods.*
~ Broad Spectrum Chewable Enzymes BioCor
General Statements
CAUTIONS/INTERACTIONS: There are no known drug interactions.
Natural color variation may occur in this product.
~ Digestive Health*
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Do Not Eat Freshness Packet. Keep in Bottle.
Not manufactured with wheat, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Brand IP Statement(s)
BioCore is a registered trademark of National Enzyme Company.
General
CODE P2957 V4
FDA Statement of Identity
A Dietary Supplement
Formulation
Vegetarian/Vegan
Not manufactured with wheat, soy, milk, egg, fish, shellfish or tree nut ingredients.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ProtoZymes by Protocol For Life Balance label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ProtoZymes by Protocol For Life Balance
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Chewable(s) Dosage formTablet Or Pill Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Fructose, Natural Flavors, Rice Dextrin, Citric Acid, Magnesium Stearate, Beet powder. These complete the product’s ingredient list but are not active constituents.
ProtoZymes by Protocol For Life Balance Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in ProtoZymes. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for ProtoZymes, from the product label.
Protocol For Life Balance
See all Protocol For Life Balance products- Name
- Protocol For Life Balance
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- www.protocolforlife.com
ProtoZymes by Protocol For Life Balance: Common Questions
Does ProtoZymes by Protocol For Life Balance interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help if I'm lactose intolerant?
Can I take this while pregnant?
What's actually in this product?
Can I take this if I have IBS or Crohn's disease?
Are there any side effects I should know about?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ProtoZymes is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ProtoZymes’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph →Sources & How We Checked
ProtoZymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC