No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pure L-Serine 500 Milligrams Ingredients & Drug Interactions

by Montiff

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Pure L-Serine 500 Milligrams is a dietary supplement by Montiff with 1 active ingredient. Its ingredients are commonly taken for memory and brain health, nervous system disorders (e.g., als research), mood and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pure L-Serine 500 Milligrams by Montiff

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-serine, an amino acid that plays a role in nerve and brain function. Each capsule delivers 500 milligrams.

The remaining ingredients — gelatin, microcrystalline cellulose, and magnesium stearate — are inactive excipients that form the capsule and help with manufacturing.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Serine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Serine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

L-serine is possibly effective for schizophrenia based on the data we hold. For Alzheimer's disease, amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's disease), back pain, post-traumatic stress disorder (PTSD), and cognitive function, the evidence isn't yet established well enough to say whether it works.

The science on long-term supplementation is still developing.

The evidence, ingredient by ingredient Serine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-serine appears to be well tolerated at medicinal doses, though side effects can be dose-dependent. The most common ones are stomach-related: abdominal pain, bloating, indigestion, loss of appetite, and nausea.

Rare serious effects like seizures have been reported only at very high doses (above 25 grams daily). During pregnancy, there isn't enough safety data, so avoid this supplement unless your doctor advises otherwise.

The same goes for breastfeeding — safety during nursing hasn't been studied, so skip it unless your healthcare provider directs you to take it.

Side effects, ingredient by ingredient Serine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for L-serine in our data. Still, it's always smart to run your exact medications through the checker on this page or ask your pharmacist to double-check before you begin.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Pure L-Serine may be worth considering if you have schizophrenia and want to explore amino acid support, though talk with your doctor first about whether it fits your plan. Pregnant or breastfeeding women should avoid it unless directed by their doctor.

If you take any medications, confirm with your pharmacist before starting — and report any stomach upset or unusual symptoms to your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure L-Serine 500 Milligrams, straight from the product label.

Brand Montiff
Barcode (UPC) 683268105856
Net contents 50 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42035
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure L-Serine 500 Milligrams by Montiff, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
50
UPC/BARCODE
683268105856
IngredientAmount% DV
L-Serine500 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one to three capsules daily, or as recommended by a health care professional. To be used as a dietary supplement in a normal food program. It is recommended that this product be taken with vitamins and minerals.

FDA Disclaimer Statement

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

DO NOT REFRIGERATE.

STORE IN A COOL, DRY PLACE.

Precautions

KEEP OUT OF REACH OF CHILDREN.

General

Product#10585

Brand IP Statement(s)

(C) 2001 MONTIFF, INC. ALL RIGHTS RESERVED.

General Statements

MONTIFF - A DON TYSON COMPANY

Highest Quality Available

FDA Statement of Identity

Dietary Supplement

Formulation

Certified free of: starch, corn, milk, wheat, yeast, sugar, eggs, salt, soy, artificial colors, binders, flavors, preservatives, fish derivatives.

See for yourself

Pure L-Serine 500 Milligrams by Montiff label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pure L-Serine 500 Milligrams by Montiff

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

L-Serine

No known
interactions
500 mg per serving

Serine is an amino acid your body can make on its own and also gets from protein-rich foods, so most people do not need a supplement. L-serine has bee...

L-Serine monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure L-Serine 500 Milligrams by Montiff Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pure L-Serine 500 Milligrams. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pure L-Serine 500 Milligrams, from the product label.

Montiff

See all Montiff products
Name
Montiff, Inc.
City
LA County
State
CA
ZipCode
90404
Pharmacist Counseling Corner

Pure L-Serine 500 Milligrams by Montiff: Common Questions

Does Pure L-Serine 500 Milligrams by Montiff interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pure L-Serine 500 Milligrams. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pure L-Serine 500 Milligrams contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-serine and what does it do?
L-serine is an amino acid — one of the building blocks your body uses to make proteins and support nerve and brain function. It's found naturally in foods and in your body, and this supplement provides a concentrated dose of it in capsule form.
Will this help my memory or brain function?
The evidence isn't established yet for general cognitive function or memory. L-serine is possibly effective for schizophrenia, but for other brain-related conditions — including Alzheimer's and other cognitive concerns — we don't have enough reliable data to say whether it works.
What side effects should I watch for?
Most commonly, people report stomach upset: belly pain, bloating, indigestion, nausea, or loss of appetite. These are usually dose-dependent, meaning higher doses are more likely to cause them. Seizures are rare but have been reported only at very high doses (well above what's in this product).
Is it safe if I'm pregnant or breastfeeding?
No — there isn't enough safety data on supplemental serine during pregnancy, so avoid it unless your doctor advises you to take it. The same applies to breastfeeding: safety hasn't been studied, so skip it unless your healthcare provider directs otherwise.
How much L-serine is in each capsule?
Each capsule contains 500 milligrams of L-serine. Follow the label or your doctor's dosing instructions — and remember that side effects can increase at higher doses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure L-Serine 500 Milligrams is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure L-Serine 500 Milligrams label
Go deeper

The Full Monographs Behind Pure L-Serine 500 Milligrams’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pure L-Serine 500 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serine 3 references
  1. Fridman V, Suriyanarayanan S, Novak P, et al. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019;92(4):e359-e370.
  2. Kantrowitz JT, Malhotra AK, Cornblatt B, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010 Aug;121(1-3):125-30. PubMed
  3. Levine TD, Miller RG, Bradley WG, et al. Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener. 2017;18(1-2):107-111. PubMed

See these in context on the Serine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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