No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pygeum 100 mg Ingredients & Drug Interactions

by NewtonEverett

Softgel Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum 100 mg is a dietary supplement by NewtonEverett with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum 100 mg by NewtonEverett

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Pygeum Bark Extract at 100 mg per softgel. Pygeum is an herbal extract from the bark of an African tree, traditionally used for prostate health.

The softgel capsule also contains several inactive ingredients — soybean oil, pumpkin seed oil, yellow beeswax, soy lecithin, gelatin, glycerin, purified water, and caramel — that help deliver and preserve the extract.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate health and urinary symptoms in men.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Urinary flow, Male urinary symptoms, Prostate function.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum Bark Extract is likely effective for benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate gland that can cause urinary symptoms in older men. For other uses listed — Alzheimer disease, malaria, sexual desire, and psychosis — the evidence we hold is insufficient to rate them.

That doesn't mean the ingredient doesn't work for those purposes; it means reliable research data isn't available to us yet.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum Bark Extract is generally well tolerated short-term, though quality and long-term safety data are limited. In clinical research, nausea and abdominal pain were reported by some participants, but at rates similar to placebo — so they weren't clearly caused by the extract itself.

Because this product is used for men's prostate health, it has no established safe use in pregnancy. If you're breastfeeding, there isn't enough safety information, so it's best avoided.

If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for Pygeum Bark Extract. Still, check your exact medications in the tool below, or ask us — it's always worth a second look.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pygeum is a solid choice if you're looking for herbal support for prostate symptoms and BPH — the evidence backs that use. It's well tolerated for short-term use, though long-term data is thin.

If you're male, take any other drugs, or have any prostate or urinary concerns, run this past us first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum 100 mg, straight from the product label.

Brand NewtonEverett
Barcode (UPC) 818423027487
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 335156
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult Male (18-50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum 100 mg by NewtonEverett, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
120
UPC/BARCODE
818423027487
IngredientAmount% DV
Pygeum Bark Extract100 mg--

Other ingredients: Soybean Oil, Pumpkin Seed Oil, Yellow Beeswax, Soy Lecithin, Gelatin, Glycerin, Water, Purified, Caramel

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Pure Potent Bioavailable We are driven to deliver highly potent, ultra-pure nutritional products with uncompromised quality. Our premium-grade liquid softgels are designed to provide an ideal delivery vehicle for maximum absorption and enhanced bioavailability.

Non-GMO Gluten free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take 1 softgel twice daily, preferably with a meal.

Precautions

Warning: This product is intended for use by men and is not intended for use by women.

If you are taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Contains: Soy. Avoid this product if you are allergic to bees or bee products.

Not suitable for vegetarians.

Storage

Store in a cool, dry place.

See for yourself

Pygeum 100 mg by NewtonEverett label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum 100 mg by NewtonEverett

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.

Pygeum Bark Extract

No known
interactions
100 mg per serving Form: Pygeum africanum Bark Extract

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum Bark Extract monograph & interactions

Other (inactive) ingredients: Soybean Oil, Pumpkin Seed Oil, Yellow Beeswax, Soy Lecithin, Gelatin, Glycerin, Water, Purified, Caramel. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum 100 mg by NewtonEverett Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum 100 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum 100 mg, from the product label.

NewtonEverett

See all NewtonEverett products
Name
Newton-Everett Nutraceuticals
Street Address
2675 S. 16th St.
City
Phoenix
State
AZ
ZipCode
85034
Web Address
newton-everett.com
Pharmacist Counseling Corner

Pygeum 100 mg by NewtonEverett: Common Questions

Does Pygeum 100 mg by NewtonEverett interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum 100 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pygeum used for?
Pygeum Bark Extract is likely effective for benign prostatic hyperplasia — that's the non-cancerous enlargement of the prostate that can cause urinary trouble in older men. It's also been studied for Alzheimer disease, sexual desire, malaria, and psychosis, but evidence for those uses is too limited for us to rate them.
Does pygeum cause side effects?
Some people in trials reported nausea and abdominal pain, but the rates were the same as placebo, so they weren't clearly caused by the extract. Overall, it's generally well tolerated short-term.
Is it safe to take pygeum long-term?
The safety data for long-term use is limited, and quality control varies. We know it's well tolerated short-term, but you should talk with your pharmacist or doctor about how long you plan to take it.
Can I take pygeum if I'm pregnant or breastfeeding?
Pygeum has no established safe use in pregnancy, so it's not recommended if you're pregnant. If you're breastfeeding, there isn't enough safety information, so it's best avoided. Talk with your doctor or pharmacist if you're in either situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum 100 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum 100 mg label
Go deeper

The Full Monographs Behind Pygeum 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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