No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Pygeum Ingredients & Drug Interactions

by Swanson

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum is a dietary supplement by Swanson with 2 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Swanson Pygeum contains two active ingredients: pygeum africanum (the whole herb) and pygeum africanum bark extract. Both are sourced from the African plum tree and serve the same purpose in this product.

The capsules also contain gelatin, microcrystalline cellulose, maltodextrin, and magnesium stearate as inactive ingredients to hold everything together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Supports prostate and urinary tract health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Lower urinary tract symptoms, Urinary flow, Bladder function.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum is likely effective for benign prostatic hyperplasia (BPH) — enlarged prostate in men — based on the evidence we hold. For Alzheimer disease, sexual desire, psychosis, and malaria, the research is too limited or unreliable to know whether it works.

If you're taking this for prostate health, the ingredient data supports its use; for other reasons, talk with your doctor about whether there's solid evidence behind it.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum has been generally well tolerated in short-term studies, though nausea and abdominal pain showed up in some trials — but at rates similar to placebo, so they're not clearly caused by the herb itself. The big caveat is that long-term safety data are limited, and quality can vary between products.

Because pygeum is used for men's prostate health, it has no established safe use in pregnancy, and there isn't enough safety information to recommend it while breastfeeding.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product. Before you take it, use the search tool on this page with your exact medications, and talk with your own doctor or pharmacist to make sure nothing changes how your drugs work.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're a man dealing with BPH symptoms, this product has solid evidence behind it and generally caused no more side effects than a dummy pill in the trials. Long-term safety data are sparse, though, so it's worth checking in with your own doctor or pharmacist before starting — especially if you take other medications or have any health conditions they should know about.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum, straight from the product label.

Brand Swanson
Barcode (UPC) 087614140971
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 266965
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
087614140971
IngredientAmount% DV
Pygeum africanum400 mg--
Pygeum africanum Bark Extract26 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Maltodextrin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

swanson.com or call 1-800-437-4148

Science-Backed Quality Since 1969

Formulation

Supports prostate health Supports urinary tract health Maintains bladder health

Prostate Health

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule two times per day with water.

Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Featuring Pygeum Bark and Extract

FDA Statement of Identity

Herbal Supplement

See for yourself

Pygeum by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum by Swanson

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pygeum africanum

No known
interactions
400 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum africanum monograph & interactions

Pygeum africanum Bark Extract

No known
interactions
26 mg per serving Form: Phytosterols

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum africanum Bark Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Maltodextrin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum by Swanson Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Pygeum by Swanson: Common Questions

Does Pygeum by Swanson interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does pygeum actually help with prostate problems?
Yes — pygeum is likely effective for benign prostatic hyperplasia (BPH), the enlarged prostate many men experience as they age. That's the condition where the evidence holds up best.
What side effects should I watch for?
Nausea and abdominal pain showed up in some clinical trials, but they happened at the same rate as placebo, so they're not clearly tied to the supplement. Most people tolerate it well in the short term.
Can I take this while breastfeeding?
No — there isn't enough safety information to recommend pygeum while breastfeeding, so it's best avoided. Talk with your doctor or pharmacist about what's safe for you and your baby.
Is this safe long-term?
The short-term data look solid, but long-term safety studies are limited. If you're thinking about taking it for months or years, that's worth discussing with your own doctor or pharmacist.
How much should I take?
The product facts don't include dosage information — check the label on your bottle, and talk with your pharmacist if you're not sure what dose is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum label
Go deeper

The Full Monographs Behind Pygeum’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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