No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Benfotiamine 300 mg Maximum Strength Ingredients & Drug Interactions

by Swanson

Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Benfotiamine 300 mg Maximum Strength is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Benfotiamine 300 mg Maximum Strength by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: benfotiamine, a fat-soluble form of thiamine (vitamin B1). Each capsule delivers 300 mg.

The remaining ingredients — rice flour, hypromellose, magnesium stearate, and silica — are inactive excipients that make up the capsule and help with manufacturing.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports healthy glucose metabolism and kidney function.
  • We looked for evidence on: Diabetic nephropathy, Diabetic neuropathy, blood sugar control, nerve health.
  • The strongest evidence on file: Benfotiamine is rated "Possibly Effective" for Diabetic neuropathy (Natural Medicines).
  • Also on file: Benfotiamine is rated "Possibly Ineffective" for Diabetic nephropathy.

Benfotiamine is possibly effective for diabetic neuropathy (nerve pain from diabetes). For diabetic kidney disease (nephropathy), the evidence suggests it's likely ineffective.

For alcohol use disorder, Alzheimer disease, and general peripheral neuropathy, we don't have enough reliable evidence to know whether it works. If you're considering it for one of these conditions, talk it over with your doctor about what the current research shows for your specific situation.

The evidence, ingredient by ingredient Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Benfotiamine is generally well tolerated in the studies we have, but long-term safety hasn't been fully studied. In one trial of 98 people taking 300–600 mg daily for 6 weeks, a small number reported allergic skin reactions and mild stomach discomfort — but these rates didn't differ from placebo.

There isn't enough safety data during pregnancy, and safety while breastfeeding hasn't been well studied, so talk with your doctor or pharmacist before using this product if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Benfotiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for benfotiamine. That said, run your specific medications through the search tool on this page, and let your doctor or pharmacist know you're taking this product.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Benfotiamine may be worth considering if you have diabetic nerve pain and your doctor thinks it's a fit for you. If you're pregnant, breastfeeding, or planning to become pregnant, check with your doctor or pharmacist first — the safety data isn't solid enough yet.

Long-term use hasn't been well studied, so have that conversation with your healthcare provider too.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine 300 mg Maximum Strength, straight from the product label.

Brand Swanson
Barcode (UPC) 087614029771
Net contents 60 Veggie Cap(s)
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 203771
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine 300 mg Maximum Strength by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614029771
IngredientAmount% DV
Benfotiamine300 mg--

Other ingredients: Rice Flour, Hypromellose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Supports healthy glucose metabolism Maintains healthy kidney function Supports healthy blood sugar levels Science-Backed Quality Since 1969

Blood sugar maintenance 300 mg per capsule

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one veggie capsule per day with water.

Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Benfotiamine 300 mg Maximum Strength by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Benfotiamine 300 mg Maximum Strength by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Benfotiamine

No known
interactions
300 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions

Other (inactive) ingredients: Rice Flour, Hypromellose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Benfotiamine 300 mg Maximum Strength by Swanson Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine 300 mg Maximum Strength. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Benfotiamine 300 mg Maximum Strength, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Benfotiamine 300 mg Maximum Strength by Swanson: Common Questions

Does Benfotiamine 300 mg Maximum Strength by Swanson interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Benfotiamine 300 mg Maximum Strength. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Benfotiamine 300 mg Maximum Strength contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is benfotiamine, and how is it different from regular B1 vitamins?
Benfotiamine is a fat-soluble form of thiamine (vitamin B1). Because it dissolves in fat rather than water, your body may absorb it differently than standard B1 supplements — that's why it's marketed as a more targeted form.
Does benfotiamine actually help with diabetic nerve pain?
The evidence suggests it's possibly effective for diabetic neuropathy. That means some research is promising, but more study is needed to be certain. Your doctor can help you weigh whether it's worth trying based on your situation.
What side effects might I experience?
In one clinical trial, a small number of people reported allergic skin reactions and mild stomach discomfort. The overall rate of side effects was no higher than placebo, so serious problems are uncommon — but they can happen.
Is it safe to take long-term?
Long-term safety hasn't been fully studied, so we don't have solid data on taking it for months or years. Talk with your doctor about whether this product is right for your needs and how long you should use it.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data during pregnancy, and safety while breastfeeding hasn't been well studied. Check with your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or breastfeeding — they can give you personalized guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Benfotiamine 300 mg Maximum Strength is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine 300 mg Maximum Strength label
Go deeper

The Full Monographs Behind Benfotiamine 300 mg Maximum Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Benfotiamine 300 mg Maximum Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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