R+ALA Ingredients & Drug Interactions
What is this page for?
First and foremost: checking R+ALA against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
R+ALA is a dietary supplement by ALLMAX ESSENTIALS with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), blood sugar support in diabetes, antioxidant support.Based on those ingredients, 263 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are R-Alpha Lipoic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against R+ALA by ALLMAX ESSENTIALS
Ask about any prescription or over-the-counter medication and we check it for interactions with R+ALA by ALLMAX ESSENTIALS — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of R+ALA by ALLMAX ESSENTIALS
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “R-Alpha Lipoic Acid” is listed as a grouped ingredient — the label gives one combined amount (150 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about R+ALA, straight from the product label.
| Brand | ALLMAX ESSENTIALS |
|---|---|
| Barcode (UPC) | 665553202655 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 296143 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for R+ALA by ALLMAX ESSENTIALS, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| R-Alpha Lipoic Acid | 150 mg | -- |
| R+ ALA Isomer | 125 mg | -- |
Other ingredients: Rice Flour, Magnesium Stearate, Hypromellose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Professional grade supplement
Vegan
Increased nutrient delivery Deactivates cell damaging free-radicals Optimizes insulin Activity
Vegan Caps
Product of USA
Formula
The R+ALA version of ALA is the purest form of Alpha Lipoic Acid. R+ALA helps the body remove sugar from the bloodstream and has an impressive ability to aid in the delivery of a wide variety of other nutrients, including creatine. Many people using R+ALA report higher energy levels for sustained periods of time. Commercially available ALA products on the market today tend to be cheaper and consist almost entirely of the S(-) isomer of Alpha Lipoic Acid. These inferior products have significantly weaker nutrient delivery and antioxidant properties. If a label does not specify R+ALA, it isn't. ALLMAX R+ALA contains a full 125 mg of the pure biologically active R+ isomer, the mitochondrial form found naturally in the human body. Make the switch to the purest most bio-active ALA, ALLMAX R+ALA.
Seals/Symbols
cGMP Registered Facility Lab Tested Every Lot
Purity & Potency Tested Quality Guaranteed
General Statements
References R. Steeper, et al. J Physiol. 1997; 273 (1 Pt 1):E185-191 K. Marangon, et al. Free Radic Biol Med. 1999; 27 (9-10):1114-1121
Brand IP Statement(s)
Copyright 2021 ALLMAX Nutrition Inc. All rights reserved. Trademarks are property of their respective owners
Science Innovation Quality Results ALLMAX ESSENTIALS
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 1-2 capsules of R+ALA 2-3 times daily. Due to the nutrient delivery properties of this product, it is recommended to take R+ALA with meals, and/or supplements that require effective nutrient delivery into muscle cells - for example creatine & protein supplements.
Precautions
Warnings: Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding or have diabetes.
Discontinue product if you experience symptoms that could suggest hypoglycemia. Do not use if inner seal is broken.
Keep out of reach of children.
California Warning: Lead is known to the State of California to cause birth defects or reproductive harm. Consuming this product can expose you to more than 0.0000005 g of lead. For more information go to www.P65Warnings.ca.gov.
Allergen Warning: Produced in a facility that also handles milk, soy, wheat, egg, peanut, tree nuts, fish, crustacean and shellfish products.
Prop 65
Storage
Store in a cool dry place away from direct sunlight.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
R+ALA by ALLMAX ESSENTIALS label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in R+ALA by ALLMAX ESSENTIALS
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
R-Alpha Lipoic Acid
Interacts with263 drugs
Alpha-lipoic acid (ALA) is an antioxidant made naturally by the body and found in small amounts in foods. It is most studied for diabetic nerve pain,...
R-Alpha Lipoic Acid monograph & interactions- › R+ ALA Isomer
Other (inactive) ingredients: Rice Flour, Magnesium Stearate, Hypromellose. These complete the product’s ingredient list but are not active constituents.
R+ALA by ALLMAX ESSENTIALS Drug Interactions
R+ALA contains a single active ingredient, and it has known interactions with 263 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against R+ALA?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in R+ALA interact with 263 drugs. Click any drug to see the details.
1 of the 1 ingredient in R+ALA interact with drugs. Each result below shows which ingredient is responsible. R-Alpha Lipoic Acid
AbciximabReoPro
How Abciximab interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of alkylating agents.
Read the full R-alpha Lipoic Acid + Altretamine interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with R+ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alpha Lipoic AcidAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-alpha Lipoic Acid + Aspirin, Caffeine, Orphenadrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in R+ALA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
R-Alpha Lipoic Acid
Alkylating Agents
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of alkylating agents.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy. Advise patients to consult their oncologist before using alpha-lipoic acid.
Anticoagulant/Antiplatelet Drugs
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro, alpha-lipoic acid inhibits platelet aggregation.
Antitumor Antibiotics
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of antitumor antibiotics.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of antitumor antibiotic drugs, which work by generating free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using alpha-lipoic acid.
Thyroid Hormone
Theoretically, alpha-lipoic acid might decrease the effects of thyroid hormone drugs.
Animal research suggests that co-administration of thyroxine with alpha-lipoic acid reduces conversion into the active T3 form.
Antidiabetes Drugs
Theoretically, taking alpha-lipoic acid with antidiabetes drugs might increase the risk of hypoglycemia.
Although some small clinical studies have suggested that alpha-lipoic acid can lower blood glucose levels, larger clinical studies in patients with diabetes have shown no clinically meaningful effect. Additionally, co-administration of single doses of alpha-lipoic acid and glyburide or acarbose did not cause detectable drug interactions in healthy volunteers.
Brand information
Manufacturer and brand details for R+ALA, from the product label.
ALLMAX ESSENTIALS
See all ALLMAX ESSENTIALS products- Name
- HBS INTERNATIONAL CORP.
- Street Address
- 711 S. Carson St., Suite 4
- City
- Carson City
- State
- NV
- ZipCode
- 89701
- Web Address
- ALLMAXNUTRITION.COM
R+ALA by ALLMAX ESSENTIALS: Common Questions
Does R+ALA by ALLMAX ESSENTIALS interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if R+ALA is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind R+ALA’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
R+ALA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 48 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Alpha-lipoic Acid 48 references
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Anon. Alpha-lipoic acid. Altern Med Rev 1998;3:308-10.
- Konrad T, Vicini P, Kusterer K, et al. Alpha-lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with Type 2 diabetes. Diabetes Care 1999;22:280-7. PubMed
- Ziegler D, Hanefeld M, Ruhnau KJ, et al. Treatment of symptomatic diabetic peripheral neuropathy with the antioxidant alpha-lipoic acid: A 3-week, multicentre randomized controlled trial (ALADIN Study). Diabetologia 1995;38:1425-33.
- Gleiter CH, Schreeb KH, Freudenthaler S, et al. Lack of interaction between thioctic acid, glibenclamide and acarbose. Br J Clin Pharmacol 1999;48:819-25. PubMed
- Jacob S, Henriksen EJ, Tritschler HJ, et al. Improvement of insulin-stimulated glucose-disposal in type 2 diabetes after repeated parenteral administration of thioctic acid. Exp Clin Endocrinol Diabet 1996;104:284-8. PubMed
- Jacob S, Henriksen EJ, Schiemann AL, et al. Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45:872-4.
- Jacob S, Ruus P, Hermann R, et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled, pilot trial. Free Rad Biol Med 1999;27:309-14.
- Segermann J, Hotze A, Ulrich H, Rao GS. Effect of alpha-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid-, protein- and glucose levels. Arzneimittelforschung 1991;41:1294-8.
- Beitner H. Randomized, placebo controlled, double-blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoaging of facial skin. Br J Dermatol 2003;149:841-9.
- Ziegler D, Nowak H, Kempler P, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A meta-analysis. Diabet Med 2004;21:114-21.
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
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