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Dietary supplement

Raspberry Ketones 250 mg Ingredients & Drug Interactions

by Natural Drugfree Solutions

Raspberry Ketones 250 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Raspberry Ketones 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Raspberry Ketones 250 mg is a dietary supplement by Natural Drugfree Solutions with 1 active ingredient. Its ingredients are commonly taken for weight loss, fat burning, boosting metabolism.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Raspberry Ketones. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Raspberry Ketones 250 mg by Natural Drugfree Solutions

Ask about any prescription or over-the-counter medication and we check it for interactions with Raspberry Ketones 250 mg by Natural Drugfree Solutions — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Raspberry Ketones 250 mg by Natural Drugfree Solutions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: raspberry ketone at 250 mg per capsule. Raspberry ketone is a naturally occurring compound structurally related to the stimulant synephrine.

The capsule also contains inactive ingredients (microcrystalline cellulose, magnesium stearate, gelatin, and water) that serve as fillers and the capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Raspberry Ketone's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports metabolism.
  • We looked for evidence on: Obesity, weight management, metabolic health.
  • The closest evidence on file: Raspberry Ketone is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence we hold does not establish that raspberry ketone is effective for alopecia areata (hair loss condition) or obesity. For both uses, the data shows insufficient reliable evidence to rate it.

If you're considering this supplement for either of these purposes, you won't find strong clinical support in the current research we have on file.

The evidence, ingredient by ingredient Raspberry Ketone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Raspberry ketone is used safely in foods, but human safety data for high supplement doses is very limited. Because raspberry ketone resembles a stimulant compound, stimulant-related side effects are possible—including heart palpitations, rapid heartbeat, elevated blood pressure, and in rare cases, serious heart rhythm disturbances.

A small number of people have also reported sweating, diarrhea, and shakiness after taking it. The safety information available advises against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Raspberry Ketone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Raspberry Ketone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take stimulant drugs (moderate risk of heart palpitations, elevated blood pressure, and dangerous arrhythmias) or warfarin or other blood thinners (moderate risk that raspberry ketone may reduce their effectiveness).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Raspberry ketone is not established as effective for the conditions it's commonly marketed for. More importantly, it carries moderate interaction risks with stimulant drugs and blood thinners like warfarin, and rare but serious heart rhythm side effects have been reported.

If you take any stimulants or anticoagulants, talk with your doctor or pharmacist before starting this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raspberry Ketones 250 mg, straight from the product label.

Brand Natural Drugfree Solutions
Barcode (UPC) 128838995692
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 219975
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raspberry Ketones 250 mg by Natural Drugfree Solutions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
128838995692
IngredientAmount% DV
Raspberry Ketones250 mg--

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate, Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Does not contain any of the major food allergens: soy, milk, egg, fish, crustacean shell fish, tree nuts, wheat, peanuts (see www.fda.gov). Gluten free.

For adult use only.

Keep out of children's reach.

If you are pregnant or nursing, or have a medical condition, consult your doctor before using this product.

FDA Disclaimer Statement

This statement has not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Raspberry ketones 250 mg per capsule

FDA Statement of Identity

Dietary Supplement

Formulation

Supports metabolism

Quality Guarantee: Certified potency and purity.

Made in the USA

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule daily, or as directed by a health care professional.

Storage

Store container tightly closed in a cool, dry place.

General Statements

Satisfaction guaranteed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Raspberry Ketones 250 mg by Natural Drugfree Solutions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Raspberry Ketones 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Raspberry Ketones 250 mg by Natural Drugfree Solutions

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Raspberry Ketones

Interacts with
174 drugs
250 mg per serving

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence th...

Raspberry Ketones monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate, Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raspberry Ketones 250 mg by Natural Drugfree Solutions Drug Interactions

Want to check YOUR meds against Raspberry Ketones 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Raspberry Ketones 174

Individual Drug Interactions

The ingredients in Raspberry Ketones 250 mg interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Raspberry Ketones 250 mg interact with drugs. Each result below shows which ingredient is responsible. Raspberry Ketones

Each ingredient & the kinds of drugs it affects

For each ingredient in Raspberry Ketones 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Raspberry Ketones2 drug types · 174 drugs

Stimulant Drugs

Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.

Likelihood Possible Evidence D
Raspberry Ketones full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Raspberry Ketones 250 mg, from the product label.

Natural Drugfree Solutions

See all Natural Drugfree Solutions products
Name
Natural Drugfree Solutions
City
Clearwater
State
FL
ZipCode
33765
Web Address
www.NaturalDrugFree.com
Pharmacist Counseling Corner

Raspberry Ketones 250 mg by Natural Drugfree Solutions: Common Questions

Does Raspberry Ketones 250 mg by Natural Drugfree Solutions interact with any medications?
Yes. Based on its ingredients, Raspberry Ketones 250 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raspberry Ketones 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is raspberry ketone safe to take if I'm pregnant or breastfeeding?
No. The safety information we have advises against concentrated supplements during pregnancy and while breastfeeding. There isn't enough data to know whether it's safe at these doses. Talk with your doctor or pharmacist for personalized advice.
Can raspberry ketone actually help me lose weight?
The evidence we hold does not show it is effective for obesity. The data rates it as having insufficient reliable evidence, which means there isn't enough strong research to confirm it works for weight loss.
What side effects might I experience?
Because raspberry ketone is structurally similar to a stimulant, stimulant-like side effects are possible—including heart palpitations, rapid heartbeat, elevated blood pressure, sweating, diarrhea, and shakiness. Rare but serious heart rhythm disturbances have been reported in case reports. Human safety data for high doses is very limited.
I'm on warfarin. Can I take this supplement?
No—not without checking with your doctor first. Raspberry ketone may reduce warfarin's effectiveness, and one patient required a significant dose increase to maintain proper blood thinning. This is a moderate interaction you need to discuss with your prescriber.
Does this product contain fillers?
Yes. It contains inactive ingredients: microcrystalline cellulose, magnesium stearate, gelatin, and water. These serve as fillers and the gelatin forms the capsule shell.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Raspberry Ketones 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raspberry Ketones 250 mg label
Go deeper

The Full Monographs Behind Raspberry Ketones 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Raspberry Ketone

Interacts with 174 drugs

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most cla...

Read the full Raspberry Ketone monograph →
Sources

Sources & How We Checked

Raspberry Ketones 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Raspberry Ketone 4 references
  1. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
  2. Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
  3. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
  4. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.

See these in context on the Raspberry Ketone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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