No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Reduced Glutathione 250 mg Ingredients & Drug Interactions

by The Vitamin Shoppe

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Reduced Glutathione 250 mg is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Reduced Glutathione 250 mg by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: reduced glutathione (Setria brand), a compound your body makes naturally to protect cells and support detoxification. Each capsule delivers 250 mg.

The remaining ingredients—rice flour, gelatin, magnesium stearate, and silicon dioxide—are inactive excipients that give the capsule its form.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Glutathione's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Antioxidant support for cellular and immune health.
  • We looked for evidence on: Aging, Chronic fatigue syndrome (CFS), Cognitive function, Cirrhosis, Nonalcoholic fatty liver disease (NAFLD), Cystic fibrosis — and 4 related terms.
  • The closest evidence on file: Glutathione is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS) (Natural Medicines).
  • Also on file: Glutathione is rated "Insufficient Reliable Evidence To Rate" for Cirrhosis, Cognitive function, Cystic fibrosis, Nonalcoholic fatty liver disease (NAFLD), and more.

The evidence for glutathione is mixed and incomplete. It's possibly effective for reducing nerve damage caused by the chemotherapy drug cisplatin.

For other uses on the label—nonalcoholic fatty liver disease, Alzheimer disease, athletic performance, and cataracts—the evidence is insufficient to rate whether it works. We don't have solid data backing those claims.

The evidence, ingredient by ingredient Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral glutathione appears generally well tolerated in short-term use, but long-term safety isn't well established. There isn't enough reliable safety information for pregnancy, so avoid it unless your doctor advises otherwise.

Breastfeeding safety is also unclear; caution and avoidance are advised. Note: this applies to oral forms; inhaled glutathione can narrow airways and cause shortness of breath and cough in people with asthma.

Side effects, ingredient by ingredient Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we checked. That doesn't mean none exist—run your exact prescriptions through the checker on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Reduced glutathione may be worth considering if you're dealing with cisplatin-related nerve damage and your oncologist supports it. If you're pregnant, breastfeeding, or thinking of long-term use, talk with your doctor or pharmacist first.

Always check your medications with the tool below before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reduced Glutathione 250 mg, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536012916
Net contents 50 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 81682
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reduced Glutathione 250 mg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
766536012916
IngredientAmount% DV
Setria250 mg--

Other ingredients: Rice Flour, Gelatin, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Antioxidant Cellular health Immune Specialty

Actual size

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free Dairy free Soy free Nut free

Does Not Contain: Corn, wheat, gluten, sugar, salt, soy, dairy, citrus, fish, preservatives, artificial colors or flavors.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) capsule up to three (3) times daily, preferably with meals.

Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Setria is a registered trademark of Kyowa Hakko.

General

Item No. VS-1291 1043960 JR 1

See for yourself

Reduced Glutathione 250 mg by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Reduced Glutathione 250 mg by The Vitamin Shoppe

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Setria

No known
interactions
250 mg per serving Form: L-Glutathione

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

Setria monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reduced Glutathione 250 mg by The Vitamin Shoppe Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Reduced Glutathione 250 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Reduced Glutathione 250 mg, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Reduced Glutathione 250 mg by The Vitamin Shoppe: Common Questions

Does Reduced Glutathione 250 mg by The Vitamin Shoppe interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Reduced Glutathione 250 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Reduced Glutathione 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this glutathione safe to take long-term?
Short-term use appears well tolerated, but we don't have enough data on long-term safety. If you're thinking of taking it regularly for months or years, ask your pharmacist or doctor whether that's right for you.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough reliable safety information for either. The data advises against it during pregnancy and breastfeeding unless your doctor tells you otherwise. Talk with your OB or pharmacist about whether the benefit outweighs the uncertainty in your situation.
Does glutathione help with liver health?
For nonalcoholic fatty liver disease, the evidence isn't solid enough yet to say whether it works. You'd need to talk with your doctor about whether it's worth trying for your specific situation.
What's Setria?
Setria is the brand name for the reduced glutathione in this product. It's a standardized, bioavailable form of the compound your body naturally produces.
Will this help my athletic performance?
The evidence for that isn't established. We don't have reliable data showing it boosts performance, so I'd skip this if that's your main reason.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reduced Glutathione 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reduced Glutathione 250 mg label
Go deeper

The Full Monographs Behind Reduced Glutathione 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Reduced Glutathione 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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