No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Reduced Glutathione Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Reduced Glutathione is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Reduced Glutathione by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutathione, a compound your body produces naturally. It's included here in oral capsule form.

The capsule itself is made from vegetarian material, and the capsule is filled with hypoallergenic plant fiber as an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutathione's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glutathione for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Cisplatin-induced neurotoxicity — rated "Possibly Effective" (Natural Medicines).

The evidence for glutathione is mixed. It's rated possibly effective for reducing nerve damage (neurotoxicity) caused by cisplatin, a chemotherapy drug — but that's a specialized medical use.

For other conditions in this product's range — nonalcoholic fatty liver disease, Alzheimer disease, athletic performance, and cataracts — the evidence we have is insufficient to say whether it works or not.

The evidence, ingredient by ingredient Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral glutathione appears generally well tolerated in the short term, though long-term safety hasn't been as thoroughly studied. If you have asthma, note that inhaled (nebulized) glutathione can trigger airway narrowing and shortness of breath — this product is oral, so that's not a concern here, but it's worth knowing if you've encountered glutathione in other forms.

During pregnancy, there isn't enough reliable safety data, so it's best avoided unless your doctor advises otherwise. The same goes for breastfeeding — safety data is limited, so caution and avoidance are advised.

Side effects, ingredient by ingredient Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Even so, it's smart to search your exact medications in the tool below before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Reduced Glutathione may be worth considering if you're looking for general antioxidant support, though the evidence for most uses is still emerging. If you're pregnant or breastfeeding, talk to your doctor or pharmacist first — the safety data isn't robust enough for us to give a clear go-ahead.

No medication interactions are documented, but always run your full medication list through the checker on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reduced Glutathione, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298002323
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 278346
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reduced Glutathione by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
766298002323
IngredientAmount% DV
L-Glutathione100 mg--

Other ingredients: hypoallergenic Plant Fiber, Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, between meals.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formulation

Supports antioxidant defenses and detoxification

Gluten-free, Non-GMO & Hypoallergenic

Gluten-free, Non-GMO & Hypoallergenic

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Setria is a registered trademark of Kyowa Bio Co., Ltd.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Reduced Glutathione by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Reduced Glutathione by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

L-Glutathione

No known
interactions
100 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

L-Glutathione monograph & interactions

Other (inactive) ingredients: Hypoallergenic Plant Fiber, Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reduced Glutathione by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Reduced Glutathione. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Reduced Glutathione, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Reduced Glutathione by Pure Encapsulations: Common Questions

Does Reduced Glutathione by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Reduced Glutathione. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Reduced Glutathione contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does glutathione actually work?
It depends on what you're using it for. For nerve damage from cisplatin chemotherapy, the evidence suggests it may help — that's our 'possibly effective' rating. For other uses like liver health, memory, sports performance, or cataracts, we don't yet have reliable evidence to say whether it works or not.
Is this safe to take long-term?
Short-term use appears well tolerated based on what we know. Long-term safety hasn't been as thoroughly studied, so if you're planning to take it for months, it's worth checking in with your pharmacist or doctor about what the evidence shows and what makes sense for your situation.
Can I take this while I'm pregnant or breastfeeding?
The safety data for glutathione during pregnancy and breastfeeding is too limited to give you a clear answer either way. Talk to your doctor or pharmacist — they can weigh your individual situation and advise you on whether it's right for you.
What's the difference between oral glutathione and inhaled glutathione?
This product is oral (you swallow it). Inhaled glutathione can trigger airway narrowing and shortness of breath in people with asthma. That side effect is specific to the inhaled form, not the oral capsule.
Does this product have any fillers I should know about?
The capsule contains hypoallergenic plant fiber as an inactive ingredient, and the capsule itself is vegetarian material. If you're sensitive to plant fibers or have specific ingredient restrictions, that's something to check with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reduced Glutathione is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reduced Glutathione label
Go deeper

The Full Monographs Behind Reduced Glutathione’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Reduced Glutathione's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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