No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Rejuve Ingredients & Drug Interactions

by Synchro

Rejuve label
See full label image
Capsule Category: Other Combinations
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rejuve against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Rejuve is a dietary supplement by Synchro with 3 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Rejuve by Synchro

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “BioHyaluronic” is listed as a grouped ingredient — the label gives one combined amount (345 mg) without saying how much of each component you get.

Synchro Rejuve contains three active ingredients. Phosphatidylcholine is a natural compound found in many foods that may support liver and digestive function.

Hyaluronic Acid is a substance your body makes naturally; it's been studied for dry eye and skin aging. The product also includes BioHyaluronic, a proprietary blend, plus inert ingredients like Medium Chain Triglyceride Oil, Glycerin, and Hypromellose to fill out the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Joint health and connective tissue support.
  • We looked for evidence on: Osteoarthritis, Wound healing, Aging, Joint comfort, Cartilage health, Synovial fluid support.
  • The closest evidence on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Aging (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Osteoarthritis, Wound healing.

The evidence for these ingredients is mixed and depends on what you're taking this product for. Phosphatidylcholine is rated possibly effective for ulcerative colitis, but the data is insufficient to rate it for nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety.

Hyaluronic Acid is rated possibly effective for dry eye and venous leg ulcers, but evidence is insufficient for aging skin, hay fever, and sexual dysfunction. The effectiveness of the BioHyaluronic blend and Aronia melancarpa Fruit Extract is not established in the data we hold.

The evidence, ingredient by ingredient Phosphatidylcholine Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated by mouth, though high doses may cause digestive upset — bloating, diarrhea, altered taste, nausea, vomiting, and increased sweating have been reported in some people. Hyaluronic Acid is generally well tolerated when applied to skin, but the safety data for oral supplements is limited, and the facts advise caution with long-term use.

Neither ingredient's safety during pregnancy or breastfeeding is well studied; talk with your doctor if you're pregnant, nursing, or planning to become pregnant.

Side effects, ingredient by ingredient Phosphatidylcholine Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. We cannot verify the safety of Aronia melancarpa Fruit Extract against your medications, so bring your medication list to your pharmacist before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Synchro Rejuve might be worth considering if you're interested in a blend aimed at skin and digestive support, but the evidence for most of its claims is weak or absent. If you're pregnant, nursing, or take any medications, check with your pharmacist before starting — especially since we cannot verify the Aronia melancarpa ingredient against your drug list.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rejuve, straight from the product label.

Brand Synchro
Barcode (UPC) 196852993567
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 336406
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rejuve by Synchro, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
30
UPC/BARCODE
196852993567
IngredientAmount% DV
Phosphatidylcholine0 NP--
Hyaluronic Acid0 NP--
BioHyaluronic345 mg--
Aronia melancarpa Fruit Extract120 mg--

Other ingredients: Medium Chain Triglyceride Oil, Glycerin, Hypromellose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The age of renewal Biochemist developed. Powered by cutting edge nutritional science.

Formula

BioHyaluronic is a proprietary complex that helps the body rebuild synovial fluid in the joints, the material responsible for lubricating and maintaining healthy cartilage.

345 mg BioHyaluronic Proprietary complex regenerates synovial tissue in the joints

Suggested/Recommended/Usage/Directions

Directions Take 2-4 capsules per day, with or without food.

Storage

Store in a cool, dark place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Connective tissue regeneration 3rd party tested Every ingredient is rigorously 3rd-party tested to ensure purity Anti-aging support Restores inflammatory balance

FDA Statement of Identity

Dietary Supplement

Precautions

Contains: Coconut, soy

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rejuve by Synchro label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rejuve label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rejuve by Synchro

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BioHyaluronic

345 mg per serving

Aronia melancarpa Fruit Extract

120 mg per serving Form: Anthocyanins

Other (inactive) ingredients: Medium Chain Triglyceride Oil, Glycerin, Hypromellose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rejuve by Synchro Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Rejuve. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Rejuve, from the product label.

Synchro

See all Synchro products
Name
Synchro
Street Address
7901 4th St N, STE 300
City
St. Petersburg
State
FL
ZipCode
33702
Web Address
www.besynchro.com
Pharmacist Counseling Corner

Rejuve by Synchro: Common Questions

Does Rejuve by Synchro interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Rejuve. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Rejuve contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this okay to take if I'm pregnant or breastfeeding?
The safety data for these ingredients during pregnancy and breastfeeding isn't well studied. Choline (related to phosphatidylcholine) is needed in pregnancy, but supplement safety beyond food sources isn't clear. Talk with your doctor or pharmacist for personalized advice before taking this product.
What side effects might I expect?
Phosphatidylcholine may cause bloating, diarrhea, nausea, altered taste, or increased sweating in some people — especially at higher doses. Hyaluronic Acid is generally well tolerated when taken by mouth, though long-term safety is not fully studied. Start with the recommended dose and report any unusual symptoms to your pharmacist.
Does hyaluronic acid actually work for skin aging?
The evidence for hyaluronic acid in aging skin is insufficient — there's not enough reliable data to say whether it's effective for that use. It is rated possibly effective for dry eye and venous leg ulcers, though.
Will this help my liver?
Phosphatidylcholine is rated possibly effective for ulcerative colitis, but the evidence for nonalcoholic fatty liver disease and alcohol-related liver disease is insufficient — we can't say it works for those conditions based on current data.
Are there any fillers or other ingredients I should know about?
The capsule contains Medium Chain Triglyceride Oil, Glycerin, Hypromellose, and Silica as inactive ingredients to make the supplement stable and absorbable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rejuve is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rejuve label
Go deeper

The Full Monographs Behind Rejuve’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph → Herb & supplement monograph

Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...

Read the full Hyaluronic Acid monograph →
Sources

Sources & How We Checked

Rejuve's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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