Resveratrol Age-Revitalizing Fruit Chews Wild Berry Ingredients & Drug Interactions
by ResVitale
What is this page for?
First and foremost: checking Resveratrol Age-Revitalizing Fruit Chews Wild Berry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Resveratrol Age-Revitalizing Fruit Chews Wild Berry is a dietary supplement by ResVitale with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, weight loss, energy and vitality.Based on those ingredients, 978 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Organic French Red Wine Polyphenol Extract, Acai juice powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale
Ask about any prescription or over-the-counter medication and we check it for interactions with Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: acai juice powder and organic French red wine polyphenol extract (a grape-derived concentrate). Acai is a South American berry included for its antioxidant content, and the grape polyphenol extract provides resveratrol and other polyphenols from red wine grapes.
The chews also contain inactive ingredients—evaporated cane syrup, rice syrup, palm oil, natural flavors, soy lecithin, corn starch, citric acid, malic acid, natural fruit and vegetable color, and glycerin—that serve as sweeteners, binders, and texturizers.
Does it work?
Moderate evidence
The evidence supporting acai for anti-aging skin, athletic performance, erectile dysfunction, high cholesterol, or weight loss is insufficient—we don't have reliable data showing it works for those uses. The grape extract in this product is possibly effective for chronic venous insufficiency (heaviness or swelling in the legs from weak vein circulation), though it showed no clear benefit for nausea from chemotherapy, hay fever symptoms, or weight loss.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated when used as food or standard supplements. The most common side effects from oral grape extract are stomach upset (abdominal pain, diarrhea, dry mouth, indigestion), headache, joint pain, and nausea; a rare case of severe allergic reaction (anaphylaxis) to grape skin has been reported.
For pregnancy, the acai supplement data is too limited to know whether it's safe, so caution is advised; the grape extract, however, is likely safe in pregnancy when not combined with alcohol. For breastfeeding, there isn't enough safety information on concentrated acai or grape supplements, so caution is warranted with both—talk it over with your doctor or pharmacist before using while nursing.
Meds to double-check
Moderate interaction found
Check before starting if you take antidiabetes drugs, anticoagulants or antiplatelet drugs (blood thinners), cyclosporine, sedatives like midazolam, or any medications your liver processes—especially those using CYP1A2, CYP2D6, CYP3A4, or CYP2E1 pathways. These interactions are Moderate severity and may reduce drug effectiveness or raise drug levels.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
If you take diabetes medications, blood thinners, cyclosporine, sedatives, or drugs metabolized by your liver (a large group), run this product through the medication checker before starting—it may interfere with how they work. Otherwise, it's generally well tolerated, though stomach upset and headache can occur.
The anti-aging claims aren't backed by solid evidence, but grape extract may help with leg swelling from weak veins. Talk with your doctor or pharmacist about whether it fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Resveratrol Age-Revitalizing Fruit Chews Wild Berry, straight from the product label.
| Brand | ResVitale |
|---|---|
| Barcode (UPC) | 094922008596 |
| Net contents | 30 Softchew(s) |
| Market status | On market |
| Date entered into DSLD | Oct 26, 2011 |
| DSLD ID | 821 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 {Calories} | -- |
| Total Carbohydrates | 4 g | 1% |
| Sugar | 3 g | -- |
| Acai juice powder | 100 mg | -- |
| Organic French Red Wine Polyphenol Extract | 80 mg | -- |
Other ingredients: evaporated Cane, Rice syrup, Palm Oil, Natural Flavors, Soy Lecithin, Corn Starch, Citric Acid, Malic Acid, natural color from fruits and vegetables, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
DIETARY SUPPLEMENT
Formulation
100% vegetarian – no artificial flavors or colors
Precautions
KEEP TIGHTLY CLOSED AND OUT OF REACH OF CHILDREN. DO NOT USE IF SEAL IS BROKEN OR MISSING.
Storage
Refrigerate after opening.
General Statements
CERTIFIED ORGANIC INGREDIENTS
FLAVOR FRUIT CHEW
Guaranteed Pure, Fresh & Effective
Helps repair age-related cell damage and restore youthful DNA* Boosts energy production in cells* Standardized formulation delivers a full 30 mg of pure trans-Resveratrol
Our French Red Wine vineyards deliver a pure concentration of Resveratrol to trigger your natural age-defying defenses and Longevity Genes. Each Chew is equal to the Resveratrol found in 12 bottles of red wine.*
Our high-ORAC berry formula provides you with the essential antioxidant support that your body craves. Oxygen Radical Absorbance Capacity (ORAC) measures the antioxidant capacity of a product. The higher the ORAC value, the more antioxidant power the product contains.
Produced under the strictest Good Manufacturing Practices (GMP), our formulas are made in an oxygen-free, nitrogen-rich environment. Each batch is tested by a certified third party analytical laboratory to confirm potency.
Resveratrol Age-Revitalizing Fruit Chews supply the nourishment needed to activate and restore youthful cellular activity. This Resveratrol supports gene activation, promoting your health and longevity.*
THE PUREST YOUTH ACTIVATING
Youth lies dormant deep inside cells. Healthy cells thrive on nourishing proteins and energy production to sustain the cycle of renewal. Reawaken youthful activity with this restorative age-revitalizing formula.*
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 1 soft chew daily. For advanced cellular protection, take 2 soft chews.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Chew(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Acai juice powder
Interacts with86 drugs
Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacki...
Acai juice powder monograph & interactionsOrganic French Red Wine Polyphenol Extract
Interacts with910 drugs
Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and b...
Organic French Red Wine Polyphenol Extract monograph & interactionsOther (inactive) ingredients: Evaporated Cane, Rice syrup, Palm Oil, Natural Flavors, Soy Lecithin, Corn Starch, Citric Acid, Malic Acid, Natural color from fruits and vegetables, Glycerin. These complete the product’s ingredient list but are not active constituents.
Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale Drug Interactions
HelloPharmacist Interaction Report
ResVitale Resveratrol Age-Revitalizing Fruit Chews interact with medications through their acai juice powder and organic French red wine polyphenol extract (grape) content.
The most serious documented interaction is Moderate severity: grape extract may reduce how your body absorbs cyclosporine (an immunosuppressant), cutting its levels by up to 30% if taken together. Spacing doses at least 2 hours apart may help.
Read the full breakdown — every affected drug type, severity by severity
Grape extract can also affect how your liver processes several categories of medications—including drugs metabolized through CYP1A2, CYP2D6, CYP3A4, and CYP2E1 pathways—either reducing or increasing their levels depending on the enzyme. The extract may also thin your blood theoretically, raising bleeding risk if you take anticoagulants or antiplatelet drugs (blood thinners).
Additionally, acai juice powder may interfere with blood sugar control if you take diabetes medications, potentially raising or lowering your fasting glucose.
Additionally, phenacetin levels may drop if you use grape juice, and long-term grape seed use might reduce how well midazolam (a sedative) works by speeding up your liver's processing of it. Altogether, these interactions span 979 individual medications.
We could not check for interactions with several other inactive ingredients in this product. Check your exact medications with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Resveratrol Age-Revitalizing Fruit Chews Wild Berry?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Resveratrol Age-Revitalizing Fruit Chews Wild Berry interact with 978 drugs. Click any drug to see the details.
2 of the 3 ingredients in Resveratrol Age-Revitalizing Fruit Chews Wild Berry interact with drugs. Each result below shows which ingredient is responsible. Organic French Red Wine Polyphenol Extract Acai juice powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic French Red Wine Polyphenol Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Acai Juice PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking acai with antidiabetes drugs might interfere with glycemic control.
Read the full Acai Juice Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic French Red Wine Polyphenol Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Resveratrol Age-Revitalizing Fruit Chews Wild Berry — through 1 ingredient. Tap an ingredient for the detail:
Organic French Red Wine Polyphenol ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Organic French Red Wine Polyphenol Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Resveratrol Age-Revitalizing Fruit Chews Wild Berry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Organic French Red Wine Polyphenol Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.
Cyclosporine (Neoral, Sandimmune)
Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.
Midazolam (Versed)
Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.
Phenacetin
Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).
Cytochrome P450 2C9 (Cyp2C9) Substrates
It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.
Acai juice powder
Antidiabetes Drugs
Theoretically, taking acai with antidiabetes drugs might interfere with glycemic control.
Preliminary clinical research in healthy adults has shown that taking acai may increase or decrease levels of fasting blood glucose.
Brand information
Manufacturer and brand details for Resveratrol Age-Revitalizing Fruit Chews Wild Berry, from the product label.
Resveratrol Age-Revitalizing Fruit Chews Wild Berry by ResVitale: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Resveratrol Age-Revitalizing Fruit Chews Wild Berry’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Acai
Interacts with 86 drugsAcai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacking for the bold health claims often atta...
Read the full Acai monograph → Herb & supplement monographGrape
Interacts with 910 drugsGrapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...
Read the full Grape monograph →Sources & How We Checked
Resveratrol Age-Revitalizing Fruit Chews Wild Berry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Acai 2 references
- Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of acai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J 2011;10:45.
- de Liz S, Cardoso AL, Copetti CLK, et al. Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study. Clin Nutr. 2020;39(12):3629-3636. PubMed
Grape 34 references
- Kiesewetter H, Koscielny J, Kalus U, et al. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II). A randomized, double-blind, placebo-controlled trial. Arzneimittelforschung
- Xiao Dong S, Zhi Ping Z, Zhong Xiao W, et al. Possible enhancement of the first-pass metabolism of phenacetin by ingestion of grape juice in Chinese subjects. Br J Clin Pharmacol 1999;48:638-40. PubMed
- Vaswani SK, Hamilton RG, Carey RN, et al. Anaphylaxis recurrent urticaria and angioedema from grape hypersensitivity. J Allergy Clin Immunol 1998;101:S31.
- Chevallier A. The Encyclopedia of Medicinal Plants. London, UK: Dorling Kindersley, Ltd., 1996.
- Bernstein DI, Bernstein CK, Deng C, et al. Evaluation of the clinical efficacy and safety of grapeseed extract in the treatment of fall seasonal allergic rhinitis: a pilot study. Ann Allergy Asthma Immunol 2002;88:272-8.. PubMed
- Greenblatt DJ, von Moltke LL, Perloff ES, et al. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 2006;79:125-33. PubMed
- Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
- Ray, S. D., Parikh, H., Hickey, E., Bagchi, M., and Bagchi, D. Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation. Mol Cell B PubMed
- O'Byrne, D. J., Devaraj, S., Grundy, S. M., and Jialal, I. Comparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults. Am J Clin.Nutr. 2002;76(6):1367-1374.
- Schaefer, E., Peil, H., Ambrosetti, L., and Petrini, O. Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial. Arzneimittelforschun PubMed
- Nishikawa, M., Ariyoshi, N., Kotani, A., Ishii, I., Nakamura, H., Nakasa, H., Ida, M., Nakamura, H., Kimura, N., Kimura, M., Hasegawa, A., Kusu, F., Ohmori, S., Nakazawa, K., and Kitada, M. Effects of continuous ingestion of green tea or grape seed extra
- de Lange, D. W., Scholman, W. L., Kraaijenhagen, R. J., Akkerman, J. W., and van de Wiel, A. Alcohol and polyphenolic grape extract inhibit platelet adhesion in flowing blood. Eur.J Clin.Invest 2004;34(12):818-824. PubMed
- Samet, J. M. and Coultas, D. B. Reduced forced vital capacity in California grape workers. What does it mean? Am Rev.Respir.Dis 1992;145(2 Pt 1):255-256. PubMed
- Gamsky, T. E., McCurdy, S. A., Samuels, S. J., and Schenker, M. B. Reduced FVC among California grape workers. Am Rev.Respir.Dis 1992;145(2 Pt 1):257-262. PubMed
- de Lange, D. W., Verhoef, S., Gorter, G., Kraaijenhagen, R. J., van de Wiel, A., and Akkerman, J. W. Polyphenolic grape extract inhibits platelet activation through PECAM-1: an explanation for the French paradox. Alcohol Clin.Exp.Res 2007;31(8):1308-1314 PubMed
- Etheridge, A. S., Black, S. R., Patel, P. R., So, J., and Mathews, J. M. An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constitu
- Krikorian, R., Nash, T. A., Shidler, M. D., Shukitt-Hale, B., and Joseph, J. A. Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr. 2010;103(5):730-734. PubMed
- Ingersoll, G. L., Wasilewski, A., Haller, M., Pandya, K., Bennett, J., He, H., Hoffmire, C., and Berry, C. Effect of concord grape juice on chemotherapy-induced nausea and vomiting: results of a pilot study. Oncol.Nurs.Forum 2010;37(2):213-221. PubMed
- Oliveira-Freitas, V. L., Dalla, Costa T., Manfro, R. C., Cruz, L. B., and Schwartsmann, G. Influence of purple grape juice in cyclosporine bioavailability. J Ren Nutr. 2010;20(5):309-313. PubMed
- Hollis, J. H., Houchins, J. A., Blumberg, J. B., and Mattes, R. D. Effects of concord grape juice on appetite, diet, body weight, lipid profile, and antioxidant status of adults. J Am Coll.Nutr. 2009;28(5):574-582. PubMed
- Dohadwala, M. M., Hamburg, N. M., Holbrook, M., Kim, B. H., Duess, M. A., Levit, A., Titas, M., Chung, W. B., Vincent, F. B., Caiano, T. L., Frame, A. A., Keaney, J. F., Jr., and Vita, J. A. Effects of Concord grape juice on ambulatory blood pressure in
- Rabe, E., Stucker, M., Esperester, A., Schafer, E., and Ottillinger, B. Efficacy and tolerability of a red-vine-leaf extract in patients suffering from chronic venous insufficiency--results of a double-blind placebo-controlled study. Eur.J Vasc.Endovasc. PubMed
- Trotta, M., Cesaretti, M., Conzi, R., Derchi, L. E., and Borgonovo, G. Elderly male with mesogastric pain. Small bowel obstruction caused by an intact fresh grape. Ann.Emerg.Med 2011;58(4):e1-e2. PubMed
- McCurdy, S. A., Wiggins, P., Schenker, M. B., Munn, S., Shaieb, A. M., Weinbaum, Z., Goldsmith, D., McGillis, S. T., Berman, B., and Samuels, S. Assessing dermatitis in epidemiologic studies: occupational skin disease among California grape and tomato ha
- Winter, C. K. and Kurtz, P. H. Factors influencing grape worker susceptibility to skin rashes. Bull.Environ.Contam Toxicol. 1985;35(3):418-426. PubMed
- Yamasaki, R., Dekio, S., and Jidoi, J. Contact dermatitis from grape bud. Contact Dermatitis 1985;12(4):226-227. PubMed
- Cox, J. and Grigg, M. Small bowel obstruction by an intact grape. J Am Geriatr.Soc 1986;34(7):550. PubMed
- Faircloth, D. E. and Robison, W. J. Obstruction of the sigmoid colon by grape seeds. JAMA 11-27-1981;246(21):2430. PubMed
- Marguerie, C. and Drouet, M. [Occupational eosinophilic lung in a grape grower: role of sulfites]. Allerg.Immunol.(Paris) 1995;27(5):163-167.
- Brito, FF., Martinez, A., Palacios, R., Mur, P., Gomez, E., Galindo, P. A., Borja, J., and Martinez, J. Rhinoconjunctivitis and asthma caused by vine pollen: a case report. J Allergy Clin Immunol 1999;103(2 Pt 1):262-266. PubMed
- Ras RT, Zock PL, Zebregs YE, et al. Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with pre- and stage I hypertension. Br J Nutr 2013;110(12):2234-41. PubMed
- Berry AC, Nakshabendi R, Abidali H, et al. Adverse effects of grape seed extract supplement: A clinical case and long-term follow-up. J Diet Suppl. 2016;13(2):232-5. PubMed
- Martínez-Maqueda D, Zapatera B, Gallego-Narbón A, Vaquero MP, Saura-Calixto F, Pérez-Jiménez J. A 6-week supplementation with grape pomace to subjects at cardiometabolic risk ameliorates insulin sensitivity, without affecting other metabolic syndrome mark
- Moon SW, Shin YU, Cho H, Bae SH, Kim HK; and for the Mogen Study Group. Effect of grape seed proanthocyanidin extract on hard exudates in patients with non-proliferative diabetic retinopathy. Medicine (Baltimore) 2019;98(21):e15515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC