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Dietary supplement

Resveratrol Antioxidant Ingredients & Drug Interactions

by NeoCell

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Resveratrol Antioxidant is a dietary supplement by NeoCell with 1 active ingredient. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Trans-Resveratrol Note: In a base of. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Resveratrol Antioxidant by NeoCell

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: trans-resveratrol, a natural compound found in grapes, berries, and red wine. Resveratrol is an antioxidant—a substance that helps protect cells from damage caused by free radicals.

The capsule also contains inactive ingredients (microcrystalline cellulose, silica, vegetable magnesium stearate, and a vegetable capsule) that serve as fillers and binders to hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Resveratrol's overall clinical evidence instead.

Moderate

Some clinical evidence supports Resveratrol for:

Why this rating?
  • The label markets general wellness (“antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Allergic rhinitis (hay fever) — rated "Possibly Effective" (Natural Medicines).
  • On file: Obesity — rated "Possibly Effective" (Natural Medicines).

The evidence for resveratrol is mixed. It's rated possibly effective for obesity and allergic rhinitis (hay fever), meaning there's some supporting research but it's not conclusive.

However, it's rated possibly ineffective for cardiovascular disease and high cholesterol—the research suggests it may not deliver the benefits people hope for in those areas. If you're considering this supplement for any of these conditions, talk with your doctor about whether the current evidence supports its use for your situation.

The evidence, ingredient by ingredient Resveratrol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Resveratrol is generally well tolerated at typical supplement doses. At higher doses, the most common side effects are digestive: diarrhea, gastrointestinal discomfort, and loose stools.

Rare cases of headache, fatigue, memory loss (in patients on peritoneal dialysis), and skin rash have been reported, though a clear cause wasn't always established. There isn't enough safety information to use concentrated resveratrol supplements during pregnancy or while breastfeeding.

If you're pregnant or nursing, talk with your doctor or pharmacist before taking this product—they can help you weigh whether it's right for you.

Side effects, ingredient by ingredient Resveratrol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Resveratrol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 823 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this supplement, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or clopidogrel)—resveratrol may increase bleeding risk. Additionally, confirm any drugs metabolized by the liver enzymes CYP2C19, CYP1A2, CYP3A4, or CYP2E1, since resveratrol may raise their levels and potentially cause side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Resveratrol may help with obesity or hay fever symptoms, but the evidence is modest. Its main drawback is that it interacts with a large number of medications by raising their blood levels, and it increases bleeding risk if you take blood thinners.

If you take any prescription medications, check them against this product with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Resveratrol Antioxidant, straight from the product label.

Brand NeoCell
Barcode (UPC) 016185129108
Net contents 150 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 35294
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Resveratrol Antioxidant by NeoCell, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Capsule(s)
Maximum serving Sizes:
5 Capsule(s)
Servings per container
30
UPC/BARCODE
016185129108
IngredientAmount% DV
Trans-Resveratrol Note: In a base of100 mg--

Other ingredients: Microcrystallline Cellulose, Silica, Vegetable Magnesium Stearate, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

DOSAGE: As a dietary supplement, take five capsules daily.

Precautions

ALLERGY WARNING: May contain sulfite residues.

WARNING: KEEP OUT OF REACH OF CHILDREN.

Resveratrol should not be taken by children under the age of 16 years old.

If you are pregnant, nursing, or have a medical condition, consult your physician before using this product.

Brand IP Statement(s)

Nutrients you can trust(R)

NeoCell(TM) Resveratrol Antioxidant is processed without exposure to high heat, chemicals or UV light, preventing oxidation and ensuring the important nutrients remain intact for the utmost quality and efficacy.

Copyright(C) 2011 NeoCell Corporation ALL RIGHTS RESERVED Nutrients you can trust is a registered trademark of NeoCell Corporation

Seals/Symbols

100% PCR

GMP CERTIFIED

NeoCell(TM)

General Statements

PRODUCT OF U.S.A.

anti-aging heart health immune support

100mg TRANS RESVERATROL PER SERVING

age-defying micronutrients for cellular rejuvenation & youthful vitality*

The addition of muscadine grapes, grape seed extract and pomegranate seed make Resveratrol Antioxidant a potent blend of natural polyphenol nutrients that assist in cellular rejuvenation.

Formulation

Knotweed FREE

This product does not contain polygonum cuspidatum (Japanese Knotweed).

knotweed free

DOES NOT CONTAIN: soy, wheat, lactose, starch, yeast, or artificial flavors. GLUTEN FREE.

FDA Statement of Identity

dietary supplement

Formula

NeoCell(TM) Resveratrol Antioxidant contains Trans-Reveratrol that is extracted from the red wine grapes, grape vine and seed from the Bordeaux region in France.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Resveratrol Antioxidant by NeoCell label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Resveratrol Antioxidant by NeoCell

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Trans-Resveratrol Note: In a base of

Interacts with
822 drugs
100 mg per serving Form: {Resveratrol} Oligomers, Muscadine Grape seed powder, Oligomeric Proanthocyanidin, Pomegranate extract, Quercetin flavonols, Resveratrol Monomers, Vitis vinifera

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

Trans-Resveratrol Note: In a base of monograph & interactions

Other (inactive) ingredients: Microcrystallline Cellulose, Silica, Vegetable Magnesium Stearate, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Resveratrol Antioxidant by NeoCell Drug Interactions

Want to check YOUR meds against Resveratrol Antioxidant?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
822Drugs
822 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Resveratrol Antioxidant with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Trans-Resveratrol Note: In a base of5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Resveratrol Antioxidant, from the product label.

NeoCell

See all NeoCell products
Name
NeoCell Corporation
City
Santa Ana
State
CA
ZipCode
92704
Phone Number
1.800.346.2922
Web Address
www.neocell.com
Pharmacist Counseling Corner

Resveratrol Antioxidant by NeoCell: Common Questions

Does Resveratrol Antioxidant by NeoCell interact with any medications?
Yes. Based on its ingredients, Resveratrol Antioxidant has a known interaction with 822 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Resveratrol Antioxidant contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know whether concentrated resveratrol supplements are safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist—they can give you personalized advice based on your situation.
What are the most common side effects?
At higher doses, digestive issues are most likely: diarrhea, gastrointestinal discomfort, and loose stools. Rare cases of headache, fatigue, and skin rash have been reported. Most people taking typical doses don't experience problems.
Does resveratrol actually work for weight loss?
The evidence rates it as possibly effective for obesity, which means there's some research support but it's not definitive. It's not a proven weight-loss remedy, so talk with your doctor about realistic expectations.
Will this help my heart health?
Research rates resveratrol as possibly ineffective for cardiovascular disease and high cholesterol. If heart health is your goal, your doctor can recommend approaches with stronger evidence.
How many active ingredients are in this product?
There's one active ingredient: trans-resveratrol. The rest is inactive ingredients that help form and stabilize the capsule.
Why might this interact with so many medications?
Resveratrol can slow down liver enzymes (CYP2C19, CYP1A2, CYP3A4, and CYP2E1) that break down a wide range of drugs. When your liver processes medications more slowly, their levels in your blood can build up, raising the risk of side effects—which is why checking your specific prescriptions matters.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Resveratrol Antioxidant label
Go deeper

The Full Monographs Behind Resveratrol Antioxidant’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Resveratrol Antioxidant's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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