Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Resveratrol Plus+ Ingredients & Drug Interactions

by Member's Mark

Resveratrol Plus+ label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Resveratrol Plus+ against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Resveratrol Plus+ is a dietary supplement by Member's Mark with 2 active ingredients. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Resveratrol Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Resveratrol Plus+ by Member's Mark

Ask about any prescription or over-the-counter medication and we check it for interactions with Resveratrol Plus+ by Member's Mark — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Resveratrol Plus+ by Member's Mark

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.
  • “Resveratrol Complex” is a proprietary blend — the label gives one combined amount (300 mg) without saying how much of each component you get.

Resveratrol Plus+ contains 3 active ingredients. The main one is trans-resveratrol, a polyphenol compound found naturally in grapes and red wine, often taken for heart and metabolic health.

It also contains trans-pterostilbene (a related polyphenol) and a blend called Resveratrol Complex, which combines resveratrol with glycosides—compounds that help your body absorb it. The capsule itself contains gelatin, rice flour, magnesium stearate, and silica as inactive fillers and binders.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Supports heart health and cardiovascular function.
  • We looked for evidence on: Cardiovascular disease (CVD), Hypercholesterolemia, Hypertension, Metabolic syndrome, Atherosclerosis, Endothelial dysfunction.
  • The closest evidence on file: Resveratrol is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Resveratrol is rated "Possibly Ineffective" for Hypercholesterolemia, Metabolic syndrome.
  • Also on file: Resveratrol is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

Resveratrol has possibly effective evidence for obesity and allergic rhinitis (hay fever)—meaning there's some research backing, but it's not conclusive. For cardiovascular disease and high cholesterol, the evidence rates as possibly ineffective, so don't count on this supplement to treat either one.

We don't hold effectiveness data for pterostilbene or the glycoside blend, so we can't comment on how much they contribute.

The evidence, ingredient by ingredient Resveratrol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Resveratrol is generally well tolerated at typical supplement doses. Higher doses can cause digestive upset—diarrhea, gastrointestinal discomfort, and loose stools are the most common side effects reported.

Long-term safety at high doses isn't fully known. Rare cases of headache, fatigue, and skin rash have been reported, though causality wasn't always confirmed.

There isn't enough safety information to recommend this supplement during pregnancy or while breastfeeding. If you're pregnant or nursing, talk with your doctor or pharmacist about whether this product is right for you before taking it.

Side effects, ingredient by ingredient Resveratrol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Resveratrol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 823 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin for heart disease)—resveratrol may increase bleeding risk. Also double-check if you're on any drugs metabolized by your liver's CYP2C19, CYP1A2, CYP3A4, or CYP2E1 enzymes, as resveratrol may raise their blood levels.

Your pharmacist can tell you if your medications fall into these groups.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Resveratrol Plus+ may be worth considering if you're interested in natural support for weight management or seasonal allergies, but the evidence is modest. The main concern is its interaction with blood thinners and with drugs your liver metabolizes—if you take any prescription medications, check them against this product first with your doctor or pharmacist.

Stick to typical doses to minimize digestive upset, and avoid it if you're pregnant or breastfeeding unless your healthcare provider gives you the go-ahead.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Resveratrol Plus+, straight from the product label.

Brand Member's Mark
Barcode (UPC) 078742091730
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2016
DSLD ID 66349
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Resveratrol Plus+ by Member's Mark, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
078742091730
IngredientAmount% DV
Trans-Resveratrol100 mg--
Trans-Pterostilbene20 mcg--
Resveratrol Complex300 mg--
Glycosides0 NP--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Supports heart health*

Cardiovascular/Antioxidant*

The secret of red wine for total heart health*

Nutrition information: Member's Mark Resveratol Plus+ has been formulated to promote cardiovascular health and to provide superior antioxidant protection. Made famous by the studies on red wine, Resveratrol has been discovered to be of important benefit to your health.

100% Money back guarantee Superior quality and performance

We would like to hear from you with any comments or suggestions. In the continental U.S. or Canada, you can call us toll-free at 1-800-352-8674 from 8 a.m. to 5 p.m. EST Monday-Friday.

1 capsule = 100 glasses of red wine (resveratrol content) and 100 blueberries (pterostilbene content)

The secret of red wine for total heart health.*

Why is this formula superior? The amount of active trans-resveratrol is key.

Others: typically contain low or trace amounts and often do not specifically state the amount of active trans-resveratrol.

Pterostilbene has been shown in laboratory tests to work synergistically with trans-resveratrol to provide enhanced antioxidant properties for anti-aging benefits.*

Part# 23317

Brand IP Statement(s)

M Member's Mark Quality Guaranteed

Formula

100 mg trans-resveratrol

100% pure active trans-resveratrol With pterostilbene for superior antioxidant protection*

Member's Mark Resveratol Plus+ contains Polygonum cuspidatum and Vitis vinifera, in order to provide you with the benefits of Resveratrol in a small, concentrated dosage.

100% pure active trans-resveratrol per dose. With Pterostilbene for superior antioxidant protection.*

Ours: contains a clinical dose, 100 mg of active trans-resveratrol.

Our formula contains Pterostilbene, an antioxidant naturally found in blueberries.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule daily with a meal. For adults only.

Precautions

For adults only. Consult your doctor before taking any supplement.

Warning: If you are pregnant, nursing or taking any prescription medication consult a doctor before using this product.

Discontinue use and consult a doctor if any adverse reactions occur.

Keep out of the reach of children.

For your protection do not use if seal under cap is broken or missing.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Keep in a cool, dry place, with cap tightly closed and avoid excessive heat.

Formulation

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, artificial color, artificial flavor.

Seals/Symbols

Laboratory Tested Quality Assured

Gluten free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Resveratrol Plus+ by Member's Mark label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Resveratrol Plus+ label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Resveratrol Plus+ by Member's Mark

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Trans-Pterostilbene

20 mcg per serving

Resveratrol Complex

Interacts with
822 drugs
300 mg per serving Form: Grapeseed, Grapeskin extract, Polygonum cuspidatum (root) extract

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

Resveratrol Complex monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Resveratrol Plus+ by Member's Mark Drug Interactions

Want to check YOUR meds against Resveratrol Plus+?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
822Drugs
822 Moderate

Ingredients driving the most interactions

Resveratrol Complex 822

Individual Drug Interactions

The ingredients in Resveratrol Plus+ interact with 822 drugs. Click any drug to see the details.

1 of the 2 ingredients in Resveratrol Plus+ interact with drugs. Each result below shows which ingredient is responsible. Resveratrol Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Resveratrol Plus+ with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Resveratrol Complex5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
Resveratrol Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Resveratrol Plus+, from the product label.

Member's Mark

Web Address
1-800-352-8674
Pharmacist Counseling Corner

Resveratrol Plus+ by Member's Mark: Common Questions

Does Resveratrol Plus+ by Member's Mark interact with any medications?
Yes. Based on its ingredients, Resveratrol Plus+ has a known interaction with 822 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Resveratrol Plus+ contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is resveratrol, and where does it come from?
Resveratrol is a natural polyphenol—a type of plant compound—found in grapes, berries, and red wine. It's included in this supplement for its potential effects on heart health, inflammation, and metabolism, though the evidence is still emerging.
Will this help me lose weight?
Resveratrol has possibly effective evidence for obesity, meaning some research supports it, but it's not conclusive. Don't expect it to do the work alone—it may work best alongside diet and exercise. Talk with your doctor if you're considering it as part of a weight management plan.
What are the most common side effects?
At higher doses, digestive upset is most likely—diarrhea, stomach discomfort, and loose stools. At typical supplement doses, it's generally well tolerated. If you notice these symptoms, try taking it with food or lowering the dose.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety information to recommend this supplement during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about your specific situation before taking it.
Why should I be careful if I take blood thinners?
Resveratrol appears to have antiplatelet effects—meaning it may thin your blood slightly. If you're already on a blood thinner like warfarin or aspirin, combining them could raise your bleeding risk. Your doctor or pharmacist can advise whether this product is safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Resveratrol Plus+ is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Resveratrol Plus+ label
Go deeper

The Full Monographs Behind Resveratrol Plus+’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Resveratrol

Interacts with 822 drugs

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...

Read the full Resveratrol monograph →
Sources

Sources & How We Checked

Resveratrol Plus+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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