Rosehip 6000 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Rosehip 6000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Rosehip 6000 mg is a dietary supplement by SimplySupplements with 1 active ingredient. Its ingredients are commonly taken for joint pain and osteoarthritis, colds and flu, source of vitamin c.Based on those ingredients, 213 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rosehip Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Rosehip 6000 mg by SimplySupplements
Ask about any prescription or over-the-counter medication and we check it for interactions with Rosehip 6000 mg by SimplySupplements — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Rosehip 6000 mg by SimplySupplements
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Rose Hip.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; lithium.
- For scale: 213 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Rosehip 6000 mg, straight from the product label.
| Brand | SimplySupplements |
|---|---|
| Barcode (UPC) | 5060208416909 |
| Net contents | 30 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2013 |
| DSLD ID | 22455 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Rosehip 6000 mg by SimplySupplements, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Rosehip Extract | 300 mg | -- |
Other ingredients: Maltodextrin, HPMC Vegetarian Capsule, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
SimplySupplements(TM)
EasyGest CAPSULES
General Statements
SUPER STRENGTH
Popular extract for joint health
Quality Assured
Product Information One of the richest sources for Vitamin C, Rosehips also contain high levels of vitamins A and B, essential fatty acids and antioxidant flavonoids.
Image is for illustration purposes only.
Image is for illustration purposes only.
- Easy to Swallow - Easy to Absorb - Easy to Digest - No Product Odour - No Bad Taste
AutoDespatch SAVE 10% and get FREE P&P on all repeat orders by having your favourite supplements conveniently scheduled and delivered automatically with our unique Auto Despatch system. Same Day Despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class! Price Match Guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!
Suggested/Recommended/Usage/Directions
Suggested Daily Intake Take one capsule daily as a food supplement or as directed by a healthcare professional.
Precautions
Important Information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.
Do not exceed stated dose.
Keep away from children at all times.
Do not use if seal is broken.
Pregnant or lactating women should consult a Doctor before using this product.
Food supplement: This product should not be used as a substitute for a varied diet.
Storage
Store in a cool dry place.
Formulation
Suitable for Vegetarians.
General
S634
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Rosehip 6000 mg by SimplySupplements label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Rosehip 6000 mg by SimplySupplements
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Rosehip Extract
Interacts with213 drugs
Rose hip is the vitamin C–rich fruit of the wild rose, used traditionally for colds and joint pain. A standardized rose hip powder has some research s...
Rosehip Extract monograph & interactionsOther (inactive) ingredients: Maltodextrin, HPMC Vegetarian Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Rosehip 6000 mg by SimplySupplements Drug Interactions
Rosehip 6000 mg contains a single active ingredient, and it has known interactions with 213 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Rosehip 6000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Rosehip 6000 mg interact with 213 drugs. Click any drug to see the details.
1 of the 1 ingredient in Rosehip 6000 mg interact with drugs. Each result below shows which ingredient is responsible. Rosehip Extract
Aspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
Read the full Rosehip Extract + Aspirin, Pentazocine interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractEstrogens Moderate
Interaction Summary
Theoretically, rose hip might increase blood levels of estrogens.
Read the full Rosehip Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of alkylating agents but might also reduce the oxidative damage caused by certain alkylating agents.
Read the full Rosehip Extract + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Rosehip 6000 mg — through 1 ingredient. Tap an ingredient for the detail:
Rosehip ExtractAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of alkylating agents but might also reduce the oxidative damage caused by certain alkylating agents.
Read the full Rosehip Extract + Bendamustine Hydrochloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Rosehip 6000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Rosehip Extract
Alkylating Agents
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of alkylating agents but might also reduce the oxidative damage caused by certain alkylating agents.
Rose hip contains vitamin C. The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. Further, some animal research suggests that the antioxidant effects of rose hip might attenuate cyclophosphamide-induced testicular toxicity. More evidence is needed to determine what effect, if any, antioxidants found in rose hip, such as vitamin C, have on the effectiveness and adverse effects of chemotherapy.
Aluminum
Theoretically, rose hip might increase the amount of aluminum absorbed from aluminum compounds.
Rose hip contains vitamin C. Theoretically, vitamin C increases the absorption of aluminum. Concomitant use might increase aluminum absorption, but the clinical significance of this is unknown. Administer rose hip two hours before or four hours after antacids.
Anticoagulant/Antiplatelet Drugs
Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that a constituent of rose hip, rugosin E, can induce platelet aggregation. This has not been shown in humans. Theoretically, concomitant use of rose hip might reduce the effectiveness of antiplatelet or anticoagulant drugs.
Antitumor Antibiotics
Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of antitumor antibiotics.
Rose hip contains the antioxidant vitamin C. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as antitumor antibiotics. In contrast, other researchers theorize that antioxidants might make antitumor antibiotic chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on antitumor antibiotic chemotherapy.
Estrogens
Theoretically, rose hip might increase blood levels of estrogens.
Rose hip contains vitamin C. Increases in plasma estrogen levels of up to 55% have occured under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. However, increases in plasma estrogen levels may occur when women who are deficient in vitamin C take supplements.
Lithium
Theoretically, rose hip might increase blood levels of lithium.
Rose hip is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, rose hip might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Aspirin
Theoretically, rose hip might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Rose hip contains vitamin C. It has been suggested that acidification of the urine by vitamin C can decrease the urinary excretion of salicylates, increasing plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion. The vitamin C content of rose hip is typically about 500 mg per 100 grams. Thus, a clinically significant interaction between rose hip and aspirin is unlikely.
Warfarin (Coumadin)
Theoretically, rose hip might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Rose hip contains vitamin C. High doses of vitamin C may reduce the response to warfarin, possibly by causing diarrhea and reducing warfarin absorption. This occurred in two people who took up to 16 grams daily of vitamin C, and resulted in decreased prothrombin time. Lower doses of 5-10 grams daily of vitamin C can also reduce warfarin absorption, but this does not seem to be clinically significant. The vitamin C content of rose hip is typically about 500 mg per 100 grams. Thus, a clinically significant interaction between rose hip and warfarin is unlikely.
Brand information
Manufacturer and brand details for Rosehip 6000 mg, from the product label.
Rosehip 6000 mg by SimplySupplements: Common Questions
Does Rosehip 6000 mg by SimplySupplements interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Rosehip 6000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Rosehip 6000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Rosehip 6000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rose Hip 24 references
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
- Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
- Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
- Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
- Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
- Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
- Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
- Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
- Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. PubMed
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
- Andersson U, Berger K, Hogberg A, et al. Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons. Eur J Clin Nutr 2012;66:585-90. PubMed
- Rein, E., Kharazmi, A., and Winther, K. A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trial. PubMed
- Winther, K., Apel, K., and Thamsborg, G. A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial. Scand J Rheumatol. 2005;34
- Teng, C. M., Kang, Y. F., Chang, Y. L., Ko, F. N., Yang, S. C., and Hsu, F. L. ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb. Thromb.Haemost. 1997;77(3):555-561. DOI
- Seifi M, Abbasalizadeh S, Mohammad-Alizadeh-Charandabi S, Khodaie L, Mirghafourvand M. The effect of Rosa (L. Rosa canina) on the incidence of urinary tract infection in the puerperium: a randomized placebo-controlled trial. Phytother Res 2018;32(1):76-83
- Parandin R, Ghowsi M, Dadbod A. Protective effects of hydroalcoholic extract of Rosa canina L. fruit on cyclophosphamide-induced testicular toxicity in mice. Avicenna J Phytomed 2023;13(1):7-17.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC