Sarsaparilla Root Extract Powder 1000 g Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Sarsaparilla Root Extract Powder 1000 g against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sarsaparilla Root Extract Powder 1000 g is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for skin conditions like psoriasis, joint pain and arthritis, general tonic or 'blood purifier'.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sarsaparilla Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product is one active ingredient: sarsaparilla root extract. It's a powder form, so you get the plant material in concentrated form.
The only inactive ingredient is dextrin, which is a thickener or filler used to make the powder easier to mix and measure.
Does it work?
Couldn't assess
The evidence for sarsaparilla isn't established in our data. We have effectiveness ratings for cancer, psoriasis, and rheumatoid arthritis, but all three show insufficient reliable evidence to rate whether it works.
That doesn't mean it doesn't work—it means the research we have isn't solid enough yet to make a claim.
How safe is it?
Well-documented data
Sarsaparilla root extract in food amounts is thought to be low-risk, but we don't have much human safety data on supplement-dose use, so caution is reasonable. The safety data advises against it during pregnancy and while breastfeeding—there simply isn't enough information to know if it's safe at those times.
One occupational concern: people who inhale sarsaparilla root dust can develop rhinitis or asthma symptoms, though that's relevant mainly to workers, not people taking the supplement by mouth.
Meds to double-check
Moderate interaction found
Check your medications if you take lithium or digoxin. Both are Moderate-severity interactions involving sarsaparilla's diuretic effect.
Use the search tool on this page to confirm your exact drugs are clear.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take lithium or digoxin, check with your pharmacist before adding this. For anyone else, the safety data is thin, and we don't have solid evidence it works for the conditions it's marketed for.
A conversation with your pharmacist or doctor about whether it makes sense for you is worth having.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sarsaparilla Root Extract Powder 1000 g, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X00191ILNN |
| Net contents | 1 Kilogram(s); 35.3 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 330650 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Sarsaparilla Root Extract Powder 1000 g per serving
Brand IP Statement(s)
BulkSupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: added sugar, soy, dairy, yeast, gluten
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 1000 mg (about 1/3 tsp) once or twice daily, or as directed by a physician.
Storage
Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place.
General Statements
Use an accurate milligram scale. New
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1000 mg Dosage formPowder Servings per container1000 Amounts shown are per serving.
Sarsaparilla Root Extract
Interacts with2 drugs
Sarsaparilla is a traditional root used in teas, tonics, and old-fashioned root beer flavoring. Modern evidence for its health claims is very limited...
Sarsaparilla Root Extract monograph & interactionsOther (inactive) ingredients: Dextrin. These complete the product’s ingredient list but are not active constituents.
Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Sarsaparilla Root Extract Powder by BulkSupplements.com does interact with a small number of medications we need to flag.
The main concern is lithium (used for mood disorders). Sarsaparilla appears to have mild diuretic properties—meaning it helps your body shed water—and this may reduce how much lithium your kidneys clear out, raising its levels in your blood.
That's a Moderate-severity interaction, and your lithium dose might need adjusting.
Read the full breakdown — every affected drug type, severity by severity
The other Moderate interaction is with digoxin (Lanoxin), a heart medication. The same diuretic effect could contribute to potassium loss, and low potassium with digoxin raises the risk of heart rhythm problems—a concern called cardiac toxicity.
Alternatively we could not check several other ingredient categories for interaction data; however, this product contains only one active ingredient. Altogether, these interactions span 2 individual medications.
If you take lithium or digoxin, run this product through the search tool below with your exact medication and dose before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sarsaparilla Root Extract Powder 1000 g?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sarsaparilla Root Extract Powder 1000 g interact with 2 drugs. Click any drug to see the details.
1 of the 1 ingredient in Sarsaparilla Root Extract Powder 1000 g interact with drugs. Each result below shows which ingredient is responsible. Sarsaparilla Root Extract
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Sarsaparilla Root Extract Powder 1000 g — through 1 ingredient. Tap an ingredient for the detail:
Sarsaparilla Root ExtractDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Read the full Sarsaparilla Root Extract + Digoxin interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Sarsaparilla Root Extract Powder 1000 g — through 1 ingredient. Tap an ingredient for the detail:
Sarsaparilla Root ExtractLithium Moderate
Interaction Summary
Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Read the full Sarsaparilla Root Extract + Lithium Carbonate (prescription Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sarsaparilla Root Extract Powder 1000 g with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sarsaparilla Root Extract
Digoxin (Lanoxin)
Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Sarsaparilla is thought to have diuretic properties, which could potentially cause potassium loss. Overuse or misuse of sarsaparilla with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Lithium
Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Sarsaparilla is thought to have diuretic properties. Due to these effects, sarsaparilla might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Sarsaparilla Root Extract Powder 1000 g, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com: Common Questions
Does Sarsaparilla Root Extract Powder 1000 g by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while pregnant or breastfeeding?
Does sarsaparilla actually work for psoriasis or arthritis?
What are the side effects?
Is this safe if I don't take any medications?
What does the dextrin do in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sarsaparilla Root Extract Powder 1000 g is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sarsaparilla Root Extract Powder 1000 g’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sarsaparilla Root Extract Powder 1000 g's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sarsaparilla 3 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Vandenplas O, Depelchin S, Toussaint G, et al. Occupational asthma caused by sarsaparilla root dust. J Allergy Clin Immunol 1996;97:1416-8. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC