Sarsaparilla Root Extract Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Sarsaparilla Root Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sarsaparilla Root Extract Powder is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for skin conditions like psoriasis, joint pain and arthritis, general tonic or 'blood purifier'.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sarsaparilla Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sarsaparilla Root Extract Powder by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Sarsaparilla Root Extract Powder by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Sarsaparilla Root Extract Powder by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Sarsaparilla Root Extract. It also includes dextrin, an inactive filler ingredient that helps with texture and flow.
That's it—no proprietary blends or hidden extras.
Does it work?
Couldn't assess
The data we hold shows insufficient evidence to rate sarsaparilla for cancer, psoriasis, or rheumatoid arthritis. We don't have enough reliable human studies to say whether it works for these uses.
If you're considering it for a specific health concern, chat with your pharmacist or doctor about what the current research actually shows.
How safe is it?
Well-documented data
Sarsaparilla root powder is likely low-risk at the food amounts most people eat, but supplement-dose safety data in humans are thin on the ground. The safety data advises against use in pregnancy and while breastfeeding.
Occupational exposure to sarsaparilla dust can trigger stuffy nose and asthma-like symptoms, though that's mainly a workplace concern rather than something relevant to taking a capsule or powder supplement.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take lithium or digoxin (Lanoxin). Both have Moderate interactions tied to sarsaparilla's potential diuretic effect, which can raise lithium levels or increase the risk of heart problems with digoxin.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take lithium or digoxin, you need to check with your pharmacist before using this product—the diuretic effect could change how these drugs work. For other people, the main caution is that human safety data at supplement doses are limited.
Avoid it if you're pregnant or nursing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sarsaparilla Root Extract Powder, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X0018VG9M9 |
| Net contents | 500 Gram(s); 17.6 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 330648 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sarsaparilla Root Extract Powder by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
1000 g per serving
Use an accurate milligram scale. New
Brand IP Statement(s)
Bulksupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 1000 mg (about 1/3 tsp) once or twice daily, or as directed by a physician.
Storage
Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sarsaparilla Root Extract Powder by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sarsaparilla Root Extract Powder by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1000 Milligram(s) Dosage formPowder Servings per container500 Amounts shown are per serving.
Sarsaparilla Root Extract
Interacts with2 drugs
Sarsaparilla is a traditional root used in teas, tonics, and old-fashioned root beer flavoring. Modern evidence for its health claims is very limited...
Sarsaparilla Root Extract monograph & interactionsOther (inactive) ingredients: Dextrin. These complete the product’s ingredient list but are not active constituents.
Sarsaparilla Root Extract Powder by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Sarsaparilla Root Extract Powder by BulkSupplements.com has documented interactions with two medications.
The most important one to watch for is lithium (used for mood disorders). Sarsaparilla is believed to have mild water-shedding (diuretic) properties, which could slow down how your body clears lithium and raise it to unsafe levels.
Your lithium dose might need adjustment if you add this supplement.
Read the full breakdown — every affected drug type, severity by severity
Digoxin (Lanoxin), a heart medication, is the other concern—also a Moderate interaction. The same diuretic effect could lead to potassium loss, and combined with digoxin, that raises the risk of heart-rhythm problems.
If you take either of these drugs, run them through the checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sarsaparilla Root Extract Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sarsaparilla Root Extract Powder interact with 2 drugs. Click any drug to see the details.
1 of the 1 ingredient in Sarsaparilla Root Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Sarsaparilla Root Extract
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Sarsaparilla Root Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Sarsaparilla Root ExtractDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Read the full Sarsaparilla Root Extract + Digoxin interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Sarsaparilla Root Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Sarsaparilla Root ExtractLithium Moderate
Interaction Summary
Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Read the full Sarsaparilla Root Extract + Lithium Carbonate (prescription Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sarsaparilla Root Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sarsaparilla Root Extract
Digoxin (Lanoxin)
Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Sarsaparilla is thought to have diuretic properties, which could potentially cause potassium loss. Overuse or misuse of sarsaparilla with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Lithium
Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Sarsaparilla is thought to have diuretic properties. Due to these effects, sarsaparilla might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Sarsaparilla Root Extract Powder, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Sarsaparilla Root Extract Powder by BulkSupplements.com: Common Questions
Does Sarsaparilla Root Extract Powder by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
Does sarsaparilla actually work for psoriasis, arthritis, or cancer?
What's the inactive ingredient (dextrin) for?
Are there any common side effects I should expect?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sarsaparilla Root Extract Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sarsaparilla Root Extract Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sarsaparilla Root Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sarsaparilla 3 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Vandenplas O, Depelchin S, Toussaint G, et al. Occupational asthma caused by sarsaparilla root dust. J Allergy Clin Immunol 1996;97:1416-8. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC