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Dietary supplement

Sarsaparilla Root Powder Ingredients & Drug Interactions

by Bixa Botanical

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sarsaparilla Root Powder is a dietary supplement by Bixa Botanical with 1 active ingredient. Its ingredients are commonly taken for skin conditions like psoriasis, joint pain and arthritis, general tonic or 'blood purifier'.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sarsaparilla, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sarsaparilla Root Powder by Bixa Botanical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: sarsaparilla root powder. Sarsaparilla is a plant root traditionally used in herbal medicine, though modern evidence for its effectiveness is limited.

There are no inactive ingredients listed for this powder form.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Sarsaparilla's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports skin and kidney health.
  • We looked for evidence on: Psoriasis, skin health, kidney function, joint health.
  • The closest evidence on file: Sarsaparilla is rated "Insufficient Reliable Evidence To Rate" for Psoriasis (Natural Medicines).

The evidence for sarsaparilla's effectiveness is not established in the data we hold. The supplement has been studied for cancer, psoriasis, and rheumatoid arthritis, but the available research is insufficient to rate whether it works for any of these conditions.

If you're considering it for a specific health concern, talk with your doctor about what the current evidence shows and whether it's right for your situation.

The evidence, ingredient by ingredient Sarsaparilla

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sarsaparilla root powder is likely low-risk when used in the small amounts you'd find in food, but human safety data for supplement doses are limited. The safety information advises against use during pregnancy and breastfeeding due to lack of adequate data — there isn't enough information to know either way whether it's safe in those situations, so talk with your doctor or pharmacist for personalized guidance.

Occupational exposure to sarsaparilla root dust can trigger rhinitis (nasal inflammation) and asthma symptoms in workers; this is primarily a workplace concern rather than a typical consumer risk.

Side effects, ingredient by ingredient Sarsaparilla

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sarsaparilla.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium or digoxin (Lanoxin), check with your doctor or pharmacist before starting this supplement. Both interactions are Moderate severity and stem from sarsaparilla's diuretic properties, which could raise lithium levels or increase the risk of heart problems with digoxin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Sarsaparilla root powder is a single-ingredient herbal supplement with limited modern evidence for the conditions it's traditionally used for. If you take lithium or digoxin, do not start this supplement without clearing it with your doctor or pharmacist first — the interactions could affect how your medications work.

For everyone else, discuss any health goals and current medications with your own healthcare provider before adding it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sarsaparilla Root Powder, straight from the product label.

Brand Bixa Botanical
Barcode (UPC) 8904289000299
Net contents 100 Gram(s); 3.5 Oz(s)
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278715
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sarsaparilla Root Powder by Bixa Botanical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
33
UPC/BARCODE
8904289000299
IngredientAmount% DV
Sarsaparilla, Powder3 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: One - two teaspoon with warm water daily after food or as directed by your health practitioner.

General Statements

Mfg. lic. no: MP25D/14/318

Over 140 years of quality trust More than a company, Bixa Botanical is a dream-to share the collective knowledge of five generations of a family with the world; secrets of herbal healing that have been painstakingly accumulated over the last 140 years. Over 500 varieties of herbs are exclusively cleaned, processed and packed in the company's ultra-modern in-house facilities.

Brand IP Statement(s)

Trademark of Bixa Botanical INC, USA

Formulation

Supports as coolant, skin & kidney health

Vegan

Non GMO

Product of India

FDA Statement of Identity

Herbal Food Supplement

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration and this product is a herbal food supplement and not intended to diagnose, treat, cure or prevent a disease.

Precautions

Warning: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.p65warnings.ca.gov/food.

This product is not intended for use by those with a serious medical condition or pregnant or lactating women. Consult your physician before use.

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in cool and dry place.

Seals/Symbols

GMP Certified Good Manufacturing Practice KLBD (Kosher)

Formula

KLBD (Kosher)

See for yourself

Sarsaparilla Root Powder by Bixa Botanical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sarsaparilla Root Powder by Bixa Botanical

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container33 Amounts shown are per serving.

Sarsaparilla, Powder

Interacts with
2 drugs
3 Gram(s) per serving Form: Hemidesmus indicus, Powder

Sarsaparilla is a traditional root used in teas, tonics, and old-fashioned root beer flavoring. Modern evidence for its health claims is very limited...

Sarsaparilla, Powder monograph & interactions
Interaction report

Sarsaparilla Root Powder by Bixa Botanical Drug Interactions

Want to check YOUR meds against Sarsaparilla Root Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Sarsaparilla Root Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sarsaparilla, Powder2 drug types · 2 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Sarsaparilla is thought to have diuretic properties, which could potentially cause potassium loss. Overuse or misuse of sarsaparilla with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.

Likelihood Possible Evidence D
Lithium

Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Sarsaparilla is thought to have diuretic properties. Due to these effects, sarsaparilla might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Sarsaparilla Root Powder, from the product label.

Bixa Botanical

See all Bixa Botanical products
Name
S.A.Herbal Bioactives LLP
Street Address
Plot No: 101, Sector - 1, Pithampur, Dist. Dhar (M.P)
State
454 775
Phone Number
+91 22 2783 1232
Web Address
[email protected]
Pharmacist Counseling Corner

Sarsaparilla Root Powder by Bixa Botanical: Common Questions

Does Sarsaparilla Root Powder by Bixa Botanical interact with any medications?
Yes. Based on its ingredients, Sarsaparilla Root Powder has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sarsaparilla Root Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety information advises against sarsaparilla during pregnancy and breastfeeding because there isn't enough data to know either way. Talk with your doctor or pharmacist to decide what's best for you.
Does sarsaparilla actually work for cancer, psoriasis, or arthritis?
The evidence for sarsaparilla in these conditions is insufficient — meaning there isn't reliable research to say whether it works. If you're interested in it for any of these, discuss it with your doctor to understand what current evidence shows.
What's in this powder besides sarsaparilla?
This is pure sarsaparilla root powder with no inactive ingredients listed.
Can I get side effects from sarsaparilla?
Supplement doses haven't been well studied in humans, so side effects aren't fully known. The main occupational concern is that inhaled sarsaparilla dust can trigger nasal inflammation and asthma symptoms in workers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sarsaparilla Root Powder label
Go deeper

The Full Monographs Behind Sarsaparilla Root Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sarsaparilla Root Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sarsaparilla 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Vandenplas O, Depelchin S, Toussaint G, et al. Occupational asthma caused by sarsaparilla root dust. J Allergy Clin Immunol 1996;97:1416-8. PubMed

See these in context on the Sarsaparilla monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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