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Dietary supplement

Skin Support 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Skin Support 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Skin Support 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Skin Support 450 mg is a dietary supplement by TerraVita Premium Collection with 2 active ingredients. Its ingredients are commonly taken for minor wounds and skin healing, skin inflammation and irritation, diaper rash.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Marigold. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Skin Support 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Skin Support 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Skin Support 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (450 mg) without saying how much of each component you get.

Skin Support contains two active ingredients: marigold (calendula) and chickweed, delivered in a 450 mg proprietary blend per capsule. Both are plant-based botanicals traditionally used in skincare formulations.

The capsule itself is made from gelatin and water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Skin support and healing.
  • We looked for evidence on: Burns, Diaper rash, Radiation dermatitis, Wound healing, Skin irritation, Minor wounds — and 1 related terms.
  • The closest evidence on file: Calendula is rated "Insufficient Reliable Evidence To Rate" for Burns (Natural Medicines).
  • Also on file: Calendula is rated "Insufficient Reliable Evidence To Rate" for Radiation dermatitis, Diaper rash, Wound healing.

The evidence on both ingredients is limited. For marigold (calendula), the data we hold shows insufficient evidence to rate its use for acne, bacterial vaginosis, burns, COPD, liver disease, or radiation dermatitis — in other words, we don't have enough reliable research to say whether it works for these purposes.

Chickweed's effectiveness for diabetes, high cholesterol, or weight loss is also rated insufficient evidence. If you're considering this product for a specific skin concern, that's a good question to bring to your doctor or pharmacist.

The evidence, ingredient by ingredient Calendula Chickweed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Marigold is generally well tolerated when applied to skin, but it can trigger allergic reactions, especially in people sensitive to ragweed, daisies, chrysanthemums, or related plants in the Asteraceae family. When taken by mouth, allergic reactions are possible, and there isn't enough safety data to recommend it during pregnancy — it's best avoided then.

Topically, rare reports include burning, itching, redness, and scaling, though the exact role of marigold in those cases wasn't always clear. Chickweed is generally considered low-risk for short-term use, but high-quality safety data are limited.

It's best avoided during pregnancy and breastfeeding because we don't have enough information to know it's safe in those situations. Topical contact dermatitis has been reported rarely.

Side effects, ingredient by ingredient Calendula Chickweed

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Calendula.
  • The most serious interaction on file is rated Minor.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take CNS depressants — sedatives, sleep aids, or other drugs that slow your central nervous system — verify with your doctor or pharmacist that this product won't interfere before you take it. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Skin Support might appeal to you if you're looking for a plant-based skincare ingredient, but know that the evidence for how well it works is incomplete. If you take CNS depressants (sedatives, sleep aids, or similar drugs), check with your doctor or pharmacist before starting.

Pregnant or breastfeeding people should talk it over with their healthcare provider before using this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Skin Support 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435139742
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 290011
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Skin Support 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435139742
IngredientAmount% DV
Proprietary Blend450 mg--
Marigold0 NP--
Chickweed0 NP--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2005 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Formula

Chickweed and Calendula (Marigold) - 450 mg

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Skin Support 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Skin Support 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Skin Support 450 mg by TerraVita Premium Collection

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

450 mg per serving

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Skin Support 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Skin Support 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Minor

Ingredients driving the most interactions

Marigold 248

Individual Drug Interactions

The ingredients in Skin Support 450 mg interact with 248 drugs. Click any drug to see the details.

1 of the 2 ingredients in Skin Support 450 mg interact with drugs. Each result below shows which ingredient is responsible. Marigold

Each ingredient & the kinds of drugs it affects

For each ingredient in Skin Support 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Marigold1 drug type · 248 drugs

Cns Depressants

Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.
Although some animal research has suggested that a saponoside constituent in calendula may have sedative effects, calendula has been used for over 30 years without reports of sedation in humans.

Likelihood Unlikely Evidence D
Marigold full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Skin Support 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Skin Support 450 mg by TerraVita Premium Collection: Common Questions

Does Skin Support 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Skin Support 450 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Skin Support 450 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Marigold (calendula), one of the active ingredients, is rated likely unsafe during pregnancy, so it's best avoided. Chickweed lacks enough safety data. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy.
Is it safe to use while breastfeeding?
Chickweed safety while breastfeeding is unknown, so avoidance is the safer choice. Marigold's lactation safety data aren't on file. Check with your doctor or pharmacist before using this product if you're nursing.
Can this cause allergic reactions?
Yes. Marigold can cause allergic reactions in sensitive people, especially those allergic to ragweed, daisies, or related plants. Chickweed has been reported to cause contact dermatitis rarely. If you have a known allergy to these plant families, avoid this product or patch-test first.
What does marigold actually do for skin?
The research we hold doesn't provide enough reliable evidence to say how well marigold works for specific skin conditions like acne or burns. It's been used traditionally in skincare, but stronger scientific evidence is needed.
How long can I safely take this?
Chickweed is generally considered low-risk for short-term use, but high-quality safety data are limited for longer-term use. Talk with your pharmacist about how long is appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Skin Support 450 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Skin Support 450 mg label
Go deeper

The Full Monographs Behind Skin Support 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calendula

Interacts with 248 drugs

Calendula is a flowering plant whose petals are used mainly in skin creams, oils, and ointments to soothe minor irritation and support wound healing. Some early research is promising for ski...

Read the full Calendula monograph → Herb & supplement monograph

Chickweed

Chickweed is a common edible wild plant traditionally used on the skin for itching and minor irritation, and taken as a tea or tincture for various complaints. Solid human studies are lackin...

Read the full Chickweed monograph →
Sources

Sources & How We Checked

Skin Support 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calendula 9 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Reider N, Komericki P, Hausen BM, et al. The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.). Contact Dermatitis 2001;45:269-72..
  3. Gol'dman II. [Anaphylactic shock after gargling with an infusion of Calendula]. Klin Med (Mosk) 1974;52:142-3.
  4. Paulsen E. Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis 2002;47:189-98. PubMed
  5. Bojadjiev C. On the sedative and hypotensive effect of preparations from the plant Calendula officinalis. Nauch Trud Visshi Med Inst Sof 1964;43:15-20.
  6. Samochowiec L. Pharmacological study of saponosides from Aralia mandshurica Rupr. et Maxim and Calendula officinalis L. Herba Pol. 1983;29:151-155.
  7. Madisetti M, Kelechi TJ, Mueller M, Amella EJ, Prentice MA. Feasibility, acceptability, and tolerability of RGN107 in the palliative wound care management of chronic wound symptoms. J Wound Care. 2017;26(Sup1):S25-S34. PubMed
  8. Final Assessment report on Calendula officinalis L., flos. European Medicines Agency: Committee on Herbal Medicinal Products (HMPC). 2018. EMA/HMPC/603409/2017. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-cal
  9. Puaratanaarunkon T, Washrawirul C, Chuenboonngarm N, Noppakun N, Asawanonda P, Kumtornrut C. Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A

See these in context on the Calendula monograph →

Chickweed 4 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Jovanovic M, Mimica-Dukic N, Poljacki M, Boza P. Erythema multiforme due to contact with weeds: a recurrence after patch testing. Contact Dermatitis 2003;48:17-25. PubMed
  3. Jovanovic, M., Poljacki, M., Mimica-Dukic, N., Boza, P., Vujanovic, Lj, Duran, V., and Stojanovic, S. Sesquiterpene lactone mix patch testing supplemented with dandelion extract in patients with allergic contact dermatitis, atopic dermatitis and non-alle
  4. Poljacki, M., Jovanovic, M., Boza, P., Mimica-Dukic, N., Petrovic, A., and Novovic, Z. [Is Vojvodina a risk area for contact weed allergies?]. Med Pregl. 2005;58(3-4):123-126. PubMed

See these in context on the Chickweed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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