Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Slimvance Core Slimming Complex Raspberry Iced Tea Ingredients & Drug Interactions

by GNC BodyDynamix

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Slimvance Core Slimming Complex Raspberry Iced Tea is a dietary supplement by GNC BodyDynamix with 6 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,063 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium, MetaVive. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains five active ingredients. Sodium is an electrolyte your body needs in small amounts but is the main interaction concern here.

Litesse Polydextrose is a fiber that aids digestion. Slimaluma (caralluma) and MetaVive (salacia) are plant extracts used in weight-loss formulas.

The fifth ingredient, Slimvance Patented Blend, is a proprietary mix we can't break down. The product also contains inactive ingredients — flavoring, citric acid, salt, sucralose, acesulfame potassium, potassium citrate, and FD&C Red #40 — which are fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Weight loss and appetite control.
  • We looked for evidence on: Obesity, Weight management, Appetite suppression, Body composition.
  • The closest evidence on file: Caralluma is rated "Possibly Ineffective" for Obesity (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Obesity.
  • Also on file: Salacia is rated "Insufficient Reliable Evidence To Rate" for Obesity.

The evidence for these ingredients in weight loss or slimming is limited. Slimaluma (caralluma) for obesity is rated possibly ineffective based on the data we hold.

MetaVive (salacia) for obesity is also insufficient evidence to know if it works. Litesse Polydextrose, Slimvance Patented Blend, and the other ingredients don't have established effectiveness ratings in our data for weight loss or slimming.

The bottom line: we don't have solid evidence this product will help you lose weight.

The evidence, ingredient by ingredient Black Psyllium Sodium Polydextrose Caralluma Salacia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is generally well tolerated at normal dietary levels, but the facts caution against sodium supplements or very high intake without medical advice — too much raises blood pressure and puts strain on the heart. Litesse Polydextrose is safe in food amounts; at supplement doses, bloating, gas, and diarrhea are common, especially above 50 grams per dose.

Slimaluma (caralluma) seems generally well tolerated short-term but may cause stomach upset, bloating, gas, constipation, and heartburn in the first two weeks; long-term safety is not well established. MetaVive (salacia) is also generally well tolerated but can cause stomach pain, diarrhea, nausea, gas, and heartburn; long-term data are limited.

Pregnancy and breastfeeding: the safety data advise against Slimaluma and MetaVive in pregnancy and lactation. Sodium is rated possibly unsafe in lactation.

Litesse Polydextrose has no safety rating on file for pregnancy or breastfeeding — there isn't enough data to know either way.

Side effects, ingredient by ingredient Black Psyllium Sodium Polydextrose Caralluma Salacia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Black Psyllium, Salacia, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,064 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check this product if you take blood pressure medications (antihypertensives), lithium, diabetes drugs, corticosteroids, didanosine, tolvaptan, or any other sodium-containing medication. Altogether, these interactions span 288 individual medications.

The sodium in this product can affect how well these drugs work or raise your sodium to unsafe levels — both are Moderate-severity risks.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a weight-loss powder with limited evidence it works. The big concern is sodium content and how it might affect blood pressure drugs, lithium, diabetes medications, corticosteroids, and HIV drugs.

If you take any prescription medication, check your exact drugs on this page before starting. Talk to your pharmacist if you're pregnant, nursing, or have high blood pressure or kidney disease.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slimvance Core Slimming Complex Raspberry Iced Tea, straight from the product label.

Brand GNC BodyDynamix
Barcode (UPC) 048107201579
Net contents 13 Oz(s); 372.9 Gram(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 219865
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.77 Gram(s)
Maximum serving Sizes:
7.77 Gram(s)
Servings per container
48
UPC/BARCODE
048107201579
IngredientAmount% DV
Calories30 Calorie(s)--
Total Carbohydrates7 Gram(s)3%
Dietary Fiber4 Gram(s)14%
Sodium90 mg4%
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
Litesse Polydextrose5 Gram(s)--
Slimaluma500 mg--
Slimvance Patented Blend450 mg--
MetaVive150 mg--

Other ingredients: Natural & Artificial flavors, Citric Acid, Salt, Sucralose, Acesulfame Potassium, Potassium Citrate, FD&C Red #40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

"A randomized clinical study of 140 healthy overweight people compared the use of Slimvance in conjunction with an 1800 calorie diet and walking plan to a placebo with the same diet and walking plan. Those on Slimvance lost almost 10 more pounds (-11.81 pounds vs. -1.91 pounds), lost over an inch more around the hips (-1.76 inches vs. -0.48 inches) and lost over an inch more around the waist (-2.12 inches vs. -0.68 inches) than the placebo group after 16 weeks. A randomized, double-blind, placebo-controlled trial of 79 healthy men and women showed a significant reduction in salivary cortisol, a key marker of stress in those who took Slimaluma compared to those who took a placebo. Use in conjunction with the diet and exercise plan available at www.slimvance.com/plan.

Notice: Significant product settling may occur.

Brand IP Statement(s)

Litesse is a trademark of DuPont used under license by GNC. MetaVive is a trademark of OmniActive Health Technologies Ltd. Slimaluma is a registered trademark of Gencor. Slimvance is a trademark of PLT Health Solutions - Laila Nutraceuticals, LLC, US Patent #8,541,383 and international patents pending.

Formulation

Appetite powder Helps you cope with everyday stress & feel fuller 6X more weight loss 3X hip & waist reduction

Natural & artificial flavors

Gluten free, porcine free.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, add one scoop to 8 fl. oz. of water, mix thoroughly and enjoy twice a day. Do not consume more than two servings per day.

Precautions

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery. Consuming this product can expose you to chemical including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov/food

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.77 Gram(s) Dosage formPowder Servings per container48 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
4 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Sodium

Interacts with
205 drugs
90 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Litesse Polydextrose

No known
interactions
5 Gram(s) per serving

Polydextrose is a man-made soluble fiber used widely in foods as a low-calorie bulking agent and prebiotic. It is generally well tolerated, though lar...

Litesse Polydextrose monograph & interactions

Slimaluma

No known
interactions
500 mg per serving

Caralluma fimbriata is an edible succulent plant from India that is marketed mainly as an appetite suppressant and weight-loss aid. Some small studies...

Slimaluma monograph & interactions

Slimvance Patented Blend

450 mg per serving Form: Curcuma longa rhizome extract, Moringa oleifera Leaf Extract, Murraya koenigii leaf extract

MetaVive

Interacts with
86 drugs
150 mg per serving Form: Salacia chinensis extract

Salacia is a plant used in Ayurvedic medicine, mostly studied for lowering blood sugar after meals. Some small human studies suggest it may modestly b...

MetaVive monograph & interactions

Other (inactive) ingredients: Natural & Artificial flavors, Citric Acid, Salt, Sucralose, Acesulfame Potassium, Potassium Citrate, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.

Interaction report

Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix Drug Interactions

Want to check YOUR meds against Slimvance Core Slimming Complex Raspberry Iced Tea?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,063Drugs
293 Moderate 1,770 Minor

Ingredients driving the most interactions

Sodium 205

Each ingredient & the kinds of drugs it affects

For each ingredient in Slimvance Core Slimming Complex Raspberry Iced Tea with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C

MetaVive1 drug type · 86 drugs

Antidiabetes Drugs

Salacia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research suggests that salacia might lower blood glucose levels.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Slimvance Core Slimming Complex Raspberry Iced Tea, from the product label.

GNC BodyDynamix

See all GNC BodyDynamix products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
slimvance.com
Pharmacist Counseling Corner

Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix: Common Questions

Does Slimvance Core Slimming Complex Raspberry Iced Tea by GNC BodyDynamix interact with any medications?
Yes. Based on its ingredients, Slimvance Core Slimming Complex Raspberry Iced Tea has a known interaction with 2,063 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slimvance Core Slimming Complex Raspberry Iced Tea contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure medicine?
Not without checking with your pharmacist first. The sodium in this powder can reduce how well blood pressure drugs work. Use the medication checker on this page to see if your specific drug is affected.
Will this help me lose weight?
The evidence doesn't support it. Caralluma is rated possibly ineffective for obesity, and salacia has insufficient evidence. The other ingredients also lack proven weight-loss benefits in our data.
What side effects might I notice?
Stomach upset is most common — bloating, gas, diarrhea, constipation, nausea, and heartburn, especially in the first two weeks. These usually ease up. Too much sodium can also raise blood pressure over time.
Is it safe to use while pregnant or breastfeeding?
The two plant extracts in this product — caralluma and salacia — should be avoided during pregnancy and breastfeeding; the safety data advise against them. Sodium is also rated possibly unsafe while breastfeeding. Talk to your doctor before using this product if you're pregnant or nursing.
Can I take this if I have diabetes?
Not without checking first. Salacia might lower blood sugar, which could cause dangerously low blood sugar if you're on diabetes medication. Talk to your pharmacist or doctor before starting.
Is there a lot of sodium in this powder?
We don't have the exact sodium amount from the label on file, but it does contain sodium, and that's why it interacts with blood pressure, lithium, and other medications. Check the label or ask your pharmacist how much sodium is in each serving.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Slimvance Core Slimming Complex Raspberry Iced Tea is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slimvance Core Slimming Complex Raspberry Iced Tea label
Go deeper

The Full Monographs Behind Slimvance Core Slimming Complex Raspberry Iced Tea’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Slimvance Core Slimming Complex Raspberry Iced Tea's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 69 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
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See these in context on the Sodium monograph →

Polydextrose 7 references
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Caralluma 1 reference
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See these in context on the Caralluma monograph →

Salacia 5 references
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See these in context on the Salacia monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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