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Dietary supplement

Slippery Elm Ingredients & Drug Interactions

by Eclectic Herb

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Slippery Elm is a dietary supplement by Eclectic Herb with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm inner bark Extract, Dried. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Slippery Elm by Eclectic Herb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This is a straightforward single-ingredient product: Slippery Elm inner bark extract in dried form. The liquid also contains alcohol and filtered water as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Slippery Elm's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: soothes digestive tract.
  • We looked for evidence on: Constipation, Diarrhea, Inflammatory bowel disease (IBD), Irritable bowel syndrome (IBS), Peptic ulcers, heartburn — and 1 related terms.
  • The closest evidence on file: Slippery Elm is rated "Insufficient Reliable Evidence To Rate" for Constipation (Natural Medicines).
  • Also on file: Slippery Elm is rated "Insufficient Reliable Evidence To Rate" for Inflammatory bowel disease (IBD), Diarrhea, Irritable bowel syndrome (IBS), Peptic ulcers.

The evidence supporting slippery elm for any common use — constipation, diarrhea, cough, inflammatory bowel disease, or cancer — is insufficient to rate. We don't have reliable data showing it works for these purposes.

If you're thinking about using it for a specific concern, it's worth talking through with us or your doctor what the actual evidence says.

The evidence, ingredient by ingredient Slippery Elm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, but high-quality safety data are limited. The pollen and direct contact can cause allergic reactions like contact dermatitis or urticaria (hives).

Safety during pregnancy hasn't been studied enough — the data advises caution. The same goes for breastfeeding: there's too little information, so caution is advised.

If you're pregnant or nursing, check with your pharmacist before starting.

Side effects, ingredient by ingredient Slippery Elm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 2,023 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check any oral medications you're on. Slippery elm's mucilage can slow their absorption and reduce how much gets into your bloodstream — a Moderate concern.

Use the medication checker below with your exact drugs, and ask your pharmacist about timing.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Slippery Elm may work for some digestive concerns, but the evidence isn't strong yet. The main thing to watch for is spacing it away from your oral medications — it can interfere with how your body absorbs them.

Talk to your pharmacist about timing, especially if you take regular prescriptions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slippery Elm, straight from the product label.

Brand Eclectic Herb
Barcode (UPC) 023363389803
Net contents 2 Fluid Ounce(s); 60 Milliliter(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 316916
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slippery Elm by Eclectic Herb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Full Dropper(s)
Maximum serving Sizes:
1 Full Dropper(s)
UPC/BARCODE
023363389803
IngredientAmount% DV
Slippery Elm inner bark Extract, Dried0 NP--

Other ingredients: Alcohol, Water, Filtered

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Soothes digestive tract

Non GMO Soy Free Gluten Free

US grown

FDA Statement of Identity

Dietary Supplement

Formula

100% Kosher

Herbal Extract

Suggested/Recommended/Usage/Directions

Suggested use: Shake well; mix 1 full dropper in water; take 3 times daily.

Storage

Store upright.

Precautions

Keep out of reach of children. Consult your health care advisor about herbs with pregnancy, infants or prescription drugs

Discontinue use if unusual symptoms occur.

Consult your health care advisor about herbs with pregnancy, infants or prescription drugs.

General Statements

@eclecticherb

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent diseases.

See for yourself

Slippery Elm by Eclectic Herb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Slippery Elm by Eclectic Herb

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Full Dropper(s) Dosage formLiquid Amounts shown are per serving.

Slippery Elm inner bark Extract, Dried

Interacts with
2,022 drugs
0 NP per serving Form: Ulmus fulva inner bark Extract, Dried

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...

Slippery Elm inner bark Extract, Dried monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Filtered. These complete the product’s ingredient list but are not active constituents.

Interaction report

Slippery Elm by Eclectic Herb Drug Interactions

Want to check YOUR meds against Slippery Elm?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,022Drugs
2,022 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Slippery Elm with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm inner bark Extract, Dried1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Slippery Elm, from the product label.

Eclectic Herb

See all Eclectic Herb products
Name
Eclectic Herb
Street Address
755 NE 6th St.
City
Gresham
State
OR
ZipCode
97030
Phone Number
503-668-4120
Web Address
eclecticherb.com
Pharmacist Counseling Corner

Slippery Elm by Eclectic Herb: Common Questions

Does Slippery Elm by Eclectic Herb interact with any medications?
Yes. Based on its ingredients, Slippery Elm has a known interaction with 2,022 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slippery Elm contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
The safety data for slippery elm in pregnancy isn't complete — there's not enough information to know either way. Talk with your pharmacist or doctor for personalized advice based on your situation.
Is it safe to breastfeed while taking slippery elm?
There's too little information on safety while breastfeeding to say for sure. Caution is advised. Check with your pharmacist or doctor before using it.
Can slippery elm cause an allergic reaction?
Yes. The pollen is an allergen, and direct contact with the bark can cause contact dermatitis or urticaria (hives). If you have a history of allergies or sensitive skin, be cautious.
Does slippery elm actually work for constipation or diarrhea?
The evidence isn't established yet — we have insufficient reliable data to say it works for either. You might see it promoted for these uses, but the science doesn't back it up strongly enough.
How long can I safely take this?
Safety data are limited overall, but slippery elm is generally well tolerated for short-term use. If you're thinking about using it long-term, talk to your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Slippery Elm is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slippery Elm label
Sources

Sources & How We Checked

Slippery Elm's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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