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Dietary supplement

Spanish Bee Pollen 1000 gm Ingredients & Drug Interactions

by Nature's Plus

Spanish Bee Pollen 1000 gm label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Spanish Bee Pollen 1000 gm against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Spanish Bee Pollen 1000 gm is a dietary supplement by Nature's Plus with 1 active ingredient. Its ingredients are commonly taken for general energy and vitality, immune support, nutritional supplement.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bee Pollen. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Spanish Bee Pollen 1000 gm by Nature's Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Spanish Bee Pollen 1000 gm by Nature's Plus — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Spanish Bee Pollen 1000 gm by Nature's Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bee pollen. Bee pollen is a mixture of pollen, nectar, enzymes, and other compounds collected by honeybees.

The inactive ingredients are microcrystalline cellulose, di-calcium phosphate, stearic acid, magnesium stearate, riboflavin, pharmaceutical glaze, and silica — these are binders, fillers, and coating materials that help form and preserve the tablet.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Bee Pollen product and its label doesn't state a use — see Bee Pollen's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on bee pollen's usefulness is mixed. It's rated possibly ineffective for athletic performance.

For other uses — including hay fever, absent periods, enlarged prostate, and cancer-related hot flashes — we don't have enough reliable evidence to say whether it works or doesn't.

The evidence, ingredient by ingredient Bee Pollen

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bee pollen is generally well tolerated by most people, but allergies are a real concern. If you have a history of seasonal pollen allergies, especially to ragweed, chrysanthemums, daisies, marigolds, or similar plants, you're at risk for serious allergic reactions — including itching, swelling, shortness of breath, lightheadedness, and anaphylaxis.

Rare but serious side effects include acute hepatitis, kidney inflammation, and kidney failure. During pregnancy, safety data suggests bee pollen may be possibly unsafe because some sources warn it might stimulate the uterus.

There isn't enough data to know how safe it is while breastfeeding, so it's best avoided during nursing. Talk with your doctor or pharmacist about whether bee pollen makes sense for you right now.

Side effects, ingredient by ingredient Bee Pollen

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bee Pollen.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any blood thinner, tell your doctor or pharmacist before starting bee pollen — it may raise your bleeding risk and make your blood thinner work too well. Double-check your exact medications with the tool on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bee pollen may help with some conditions, but evidence is thin for most uses. If you're on warfarin or other blood thinners, check with your doctor or pharmacist before taking it — the bleeding risk is real.

If you have pollen allergies, be cautious because serious allergic reactions are possible. Any questions about whether this is right for you belong with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Spanish Bee Pollen 1000 gm, straight from the product label.

Brand Nature's Plus
Barcode (UPC) 097467037854
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Oct 25, 2012
DSLD ID 13094
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Spanish Bee Pollen 1000 gm by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
097467037854
IngredientAmount% DV
Bee Pollen1000 mg--

Other ingredients: Microcrystalline Cellulose, Di-Calcium Phosphate, Stearic Acid, Magnesium Stearate, Riboflavin, Pharmaceutical Glaze, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Nutritional Support for General Well-Being.*

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, one tablet three times daily.

Precautions

Hypo-Allergenic

KEEP OUT OF REACH OF CHILDREN.

Brand IP Statement(s)

The Energy Supplements(R)

(C)NATURAL ORGANICS(R)

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GLUTEN Free

QUALITY NATURAL SUPPLEMENTS(R)

Formula

Nature’s Plus uses only 100% pure Bee Pollen from Spain.

Formulation

Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, corn, soy and milk.

Storage

KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

PRODUCT NO. 3785 LBL. 1128752

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Spanish Bee Pollen 1000 gm by Nature's Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Spanish Bee Pollen 1000 gm label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Spanish Bee Pollen 1000 gm by Nature's Plus

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Bee Pollen

Interacts with
2 drugs
1000 mg per serving

Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most...

Bee Pollen monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Di-Calcium Phosphate, Stearic Acid, Magnesium Stearate, Riboflavin, Pharmaceutical Glaze, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Spanish Bee Pollen 1000 gm by Nature's Plus Drug Interactions

Want to check YOUR meds against Spanish Bee Pollen 1000 gm?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Bee Pollen 2

Individual Drug Interactions

The ingredients in Spanish Bee Pollen 1000 gm interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Spanish Bee Pollen 1000 gm interact with drugs. Each result below shows which ingredient is responsible. Bee Pollen

Each ingredient & the kinds of drugs it affects

For each ingredient in Spanish Bee Pollen 1000 gm with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bee Pollen1 drug type · 2 drugs

Warfarin (Coumadin)

There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.

Likelihood Possible Evidence D
Bee Pollen full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Spanish Bee Pollen 1000 gm, from the product label.

Nature's Plus

See all Nature's Plus products
Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd.
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Spanish Bee Pollen 1000 gm by Nature's Plus: Common Questions

Does Spanish Bee Pollen 1000 gm by Nature's Plus interact with any medications?
Yes. Based on its ingredients, Spanish Bee Pollen 1000 gm has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Spanish Bee Pollen 1000 gm contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have seasonal allergies?
Be careful. If you're allergic to ragweed, daisies, chrysanthemums, marigolds, or similar plants, bee pollen can trigger serious reactions — including anaphylaxis. If you have pollen allergies, talk to your doctor or pharmacist first.
Is bee pollen safe during pregnancy?
The safety data suggests bee pollen may be possibly unsafe in pregnancy because some sources warn it could stimulate the uterus. You'll want to discuss this with your doctor or pharmacist before taking it if you're pregnant or trying to conceive.
Can I take it while breastfeeding?
There isn't enough data to know whether bee pollen is safe while breastfeeding, so it's best avoided. Talk with your doctor or pharmacist about safer options while you're nursing.
What does bee pollen actually do?
We don't have strong evidence that it works for most conditions people try it for — like hay fever or enlarged prostate. It's rated possibly ineffective for athletic performance.
Are there serious side effects?
Most people tolerate it well, but rare serious side effects include acute hepatitis, kidney inflammation, and kidney failure. Allergic reactions — sometimes severe — are also possible, especially in people with pollen allergies.
Why can't I take this with warfarin?
Bee pollen may increase your bleeding risk and make warfarin work too well, raising your INR (blood-thinning measure) to unsafe levels. One case showed a patient's INR nearly double after starting bee pollen. Check with your doctor or pharmacist before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Spanish Bee Pollen 1000 gm is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Spanish Bee Pollen 1000 gm label
Go deeper

The Full Monographs Behind Spanish Bee Pollen 1000 gm’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bee Pollen

Interacts with 2 drugs

Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...

Read the full Bee Pollen monograph →
Sources

Sources & How We Checked

Spanish Bee Pollen 1000 gm's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bee Pollen 15 references
  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Shad JA, Chinn CG, Brann OS. Acute hepatitis after ingestion of herbs. South Med J 1999;92:1095-7. PubMed
  5. Puente S, Iniguez A, Subirats M, et al. [Eosinophilic gastroenteritis caused by bee pollen sensitization]. Med Clin (Barc) 1997;108:698-700.
  6. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  7. Cohen SH, Yunginger JW, Rosenberg N, Fink JN. Acute allergic reaction after composite pollen ingestion. J Allergy Clin Immunol 1979;64:270-4. PubMed
  8. Hurren KM, Lewis CL. Probable interaction between warfarin and bee pollen. Am J Health Syst Pharm 2010;67:2034-7. PubMed
  9. Akiyasu T, Paudyal B, Paudyal P, et al. A case report of acute renal failure associated with bee pollen contained in nutritional supplements. Ther Apher Dial 2010;14:93-7. PubMed
  10. Greenberger, P. A. and Flais, M. J. Bee pollen-induced anaphylactic reaction in an unknowingly sensitized subject. Ann.Allergy Asthma Immunol 2001;86(2):239-242. PubMed
  11. Lin FL, Vaughan TR, Vandewalker ML, et al. Hypereosinophilia, neurologic, and gastrointestinal symptoms after bee-pollen ingestion. J Allergy Clin Immunol 1989;83(4):793-796. PubMed
  12. Mansfield LE, Goldstein GB. Anaphylactic reaction after ingestion of local bee pollen. Ann Allergy 1981;47(3):154-156.
  13. Choi JH, Jang YS, Oh JW, Kim CH, Hyun IG. Bee pollen-induced anaphylaxis: a case report and literature review. Allergy Asthma Immunol Res 2015 Sep;7(5):513-7. PubMed
  14. Nonotte-Varly C. Allergenicity of Artemisia contained in bee pollen is proportional to its mass. Eur Ann Allergy Clin Immunol 2015;47(6):218-24.
  15. Leang ZX, Thalayasingam M, O'Sullivan M. A paediatric case of exercise-augmented anaphylaxis following bee pollen ingestion in Western Australia. Asia Pac Allergy. 2022 Jul 12;12(3):e23. PubMed

See these in context on the Bee Pollen monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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