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Dietary supplement

Advanced Therapeutics Glucofit Rx-Blood Sugar Ingredients & Drug Interactions

by Nature's Plus

Advanced Therapeutics Glucofit Rx-Blood Sugar label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Advanced Therapeutics Glucofit Rx-Blood Sugar against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Advanced Therapeutics Glucofit Rx-Blood Sugar is a dietary supplement by Nature's Plus with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, weight management.Based on those ingredients, 299 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GlucoFit(TM). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: GlucoFit, a banaba extract. Banaba is a plant used in traditional medicine, and this extract is meant to support blood sugar levels.

The softgel also contains inactive ingredients — rice bran oil, gelatin, glycerin, silica, water, and carob extract — that serve as the capsule and carrier.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Banaba's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: nutritionally supports healthy blood sugar levels.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Glycemic control, Glucose metabolism.
  • The closest evidence on file: Banaba is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Banaba is rated "Insufficient Reliable Evidence To Rate" for Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The evidence for banaba in this product isn't established yet. We have insufficient reliable evidence to rate its effectiveness for diabetes, prediabetes (impaired glucose tolerance), or metabolic syndrome.

That doesn't mean it doesn't work — it means the research so far isn't robust enough to say either way.

The evidence, ingredient by ingredient Banaba

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Banaba extract appears to be generally well tolerated in short-term studies, but we don't have solid long-term safety data. Some people in trials reported dizziness, headache, tremor, weakness, stomach upset, sweating, heart palpitations, and shakiness, though it's unclear whether banaba alone or a combination product caused them.

During pregnancy, the safety data advises against use. There isn't enough reliable information on breastfeeding safety either, so it's best avoided while nursing.

Side effects, ingredient by ingredient Banaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Banaba.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 299 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check it against any antidiabetes drugs (blood sugar medications) and antihypertensive drugs (blood pressure medications) you use — both can have Moderate-severity additive effects with banaba. Also check any medications that are substrates of OATP, a transporter in your gut and liver; banaba may reduce how much of these drugs your body absorbs.

Use the medication checker below to verify your prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood sugar or blood pressure medications, this product needs a careful check with your exact prescriptions before you start — the interactions are real. If you're pregnant or breastfeeding, the safety data isn't there, so talk to your doctor or pharmacist first.

For anyone else considering it, keep in mind the evidence for blood sugar support isn't solid yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Advanced Therapeutics Glucofit Rx-Blood Sugar, straight from the product label.

Brand Nature's Plus
Barcode (UPC) 097467045019
Net contents 0 Not Present
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13328
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
097467045019
IngredientAmount% DV
GlucoFit(TM)2.67 mg--

Other ingredients: Rice Bran Oil, Gelatin, Glycerin, Silica, Water, Carob extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, one softgel daily with a meal or as recommended by your health care practitioner.

General Statements

Nutritionally Supports Healthy Blood Sugar Levels in those individuals already within normal ranges.*

THIS IS NOT A PRESCRIPTION PRODUCT. It is a dietary supplement made with the highest possible quality standards.

Formula

HYPO-ALLERGENIC.

Each softgel provides 480 mcg of corosolic acid for peak effectiveness.

General

PRODUCT NO. 4501 LBL. 1126740

Seals/Symbols

GLUTEN Free

Brand IP Statement(s)

Div. of Natural Organics, Inc. (C)NATURAL ORGANICS(R)

The Energy Supplements(R)

Advanced Therapeutics GlucoFit(TM) Rx-Blood Sugar(R) is a precisely calibrated nutritional formulation born from leading-edge scientific studies and clinical evaluation.

GlucoFit(TM) Rx-Blood Sugar(R) is a unique specialty formula designed for any individual concerned with promoting overall well-being.

GlucoFit(TM) is a trademark of Soft Gel Technologies, Inc.(TM)

Formulation

Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, corn, soy and milk.

Storage

KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.

Precautions

KEEP OUT OF REACH OF CHILDREN.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Advanced Therapeutics Glucofit Rx-Blood Sugar label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

GlucoFit(TM)

Interacts with
299 drugs
2.67 mg per serving Form: Corosolic Acid

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may m...

GlucoFit(TM) monograph & interactions

Other (inactive) ingredients: Rice Bran Oil, Gelatin, Glycerin, Silica, Water, Carob extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus Drug Interactions

Want to check YOUR meds against Advanced Therapeutics Glucofit Rx-Blood Sugar?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
299Drugs
299 Moderate

Ingredients driving the most interactions

GlucoFit(TM) 299

Individual Drug Interactions

The ingredients in Advanced Therapeutics Glucofit Rx-Blood Sugar interact with 299 drugs. Click any drug to see the details.

1 of the 1 ingredient in Advanced Therapeutics Glucofit Rx-Blood Sugar interact with drugs. Each result below shows which ingredient is responsible. GlucoFit(TM)

Each ingredient & the kinds of drugs it affects

For each ingredient in Advanced Therapeutics Glucofit Rx-Blood Sugar with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

GlucoFit(TM)3 drug types · 299 drugs

Antidiabetes Drugs

Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Human and animal research suggests that banaba can lower blood glucose levels.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Human and animal research suggests that banaba can lower blood pressure.

Likelihood Probable Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
In vitro research shows that banaba inhibits OATP, particularly OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.

Likelihood Possible Evidence D
GlucoFit(TM) full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Advanced Therapeutics Glucofit Rx-Blood Sugar, from the product label.

Nature's Plus

See all Nature's Plus products
Name
Nature's Plus, Div. of Natural Organics, Inc.
Street Address
548 Broadhollow Rd.
City
Melville
State
NY
ZipCode
11747
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus: Common Questions

Does Advanced Therapeutics Glucofit Rx-Blood Sugar by Nature's Plus interact with any medications?
Yes. Based on its ingredients, Advanced Therapeutics Glucofit Rx-Blood Sugar has a known interaction with 299 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Advanced Therapeutics Glucofit Rx-Blood Sugar contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does banaba actually help with blood sugar?
The evidence isn't clear yet. We have insufficient reliable evidence to rate whether banaba works for diabetes, prediabetes, or metabolic syndrome. You'd want to talk with your doctor about whether it's right for your situation.
Can I take this if I'm on diabetes or blood pressure medication?
Not without checking first. Banaba may lower blood sugar and blood pressure on its own, so combining it with those medications could cause your levels to drop more than intended. Run your exact prescriptions through the medication checker on this page.
Is banaba safe to take long-term?
We don't have solid long-term safety data yet. Short-term studies show it's generally well tolerated, but we need more research on what happens with months or years of use.
Can I use this if I'm pregnant or breastfeeding?
No — the safety data advises against it in pregnancy, and there isn't enough reliable information on breastfeeding safety. Talk with your doctor or pharmacist about your options.
What side effects have been reported?
Some people in trials reported dizziness, headache, tremor, weakness, stomach upset, sweating, and heart palpitations. It's not always clear whether banaba alone caused them or a combination of ingredients in that product, but these are the effects that came up.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Advanced Therapeutics Glucofit Rx-Blood Sugar is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Advanced Therapeutics Glucofit Rx-Blood Sugar label
Go deeper

The Full Monographs Behind Advanced Therapeutics Glucofit Rx-Blood Sugar’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Banaba

Interacts with 299 drugs

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may modestly lower glucose. The overall evide...

Read the full Banaba monograph →
Sources

Sources & How We Checked

Advanced Therapeutics Glucofit Rx-Blood Sugar's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Banaba 7 references
  1. Judy WV, Hari SP, Stogsdill WW, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol 2003;87:115-7. PubMed
  2. Kakuda T, Sakane I, Takihara T, et al. Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice. Biosci Biotechnol Biochem 1996;60:204-8.
  3. Fukushima, M., Matsuyama, F., Ueda, N., Egawa, K., Takemoto, J., Kajimoto, Y., Yonaha, N., Miura, T., Kaneko, T., Nishi, Y., Mitsui, R., Fujita, Y., Yamada, Y., and Seino, Y. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res C PubMed
  4. Yamaguchi, Y., Yamada, K., Yoshikawa, N., Nakamura, K., Haginaka, J., and Kunitomo, M. Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 11-25-2006;79(26):2474-2479. PubMed
  5. Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. PubMed
  6. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
  7. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple

See these in context on the Banaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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