No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Strong Joints Ingredients & Drug Interactions

by Bare Performance Nutrition

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Strong Joints is a dietary supplement by Bare Performance Nutrition with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Strong Joints by Bare Performance Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “UC-II” is listed as a grouped ingredient — the label gives one combined amount (40 mg) without saying how much of each component you get.

Strong Joints has 3 active ingredients. Hyaluronic Acid is a naturally occurring compound that holds water and may help with joint lubrication and skin hydration.

OptiMSM is a form of sulfur thought to support connective tissue. UC-II is a standardized collagen peptide, and Total Collagen rounds out the formula — both are meant to provide building blocks for cartilage and joint structure.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hyaluronic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Joint support.
  • We looked for evidence on: Osteoarthritis, Exercise-induced muscle soreness, Joint pain, Joint mobility.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.

The evidence for this product's ingredients is mixed. Hyaluronic Acid is possibly effective for dry eye and venous leg ulcers (leg wounds from poor circulation), but for aging skin, hay fever, and sexual dysfunction the evidence is too weak to rate.

We don't have effectiveness data on file for OptiMSM, UC-II, or Total Collagen — the evidence isn't established in our database for those components.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic Acid is generally well tolerated when swallowed or applied to skin, though the long-term safety of oral supplements hasn't been fully studied. Safety information for this ingredient is limited, so it's wise to clear it with your doctor before taking it as an oral supplement.

When applied to skin, occasional eczema, redness, itching, or minor wound issues have been reported. We don't have safety data on file for OptiMSM, UC-II, or Total Collagen.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we have no interaction data for OptiMSM, UC-II, or Total Collagen, so check your exact medications with the tool on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Strong Joints may appeal to you if you're looking to support joint health with collagen and hyaluronic acid, though evidence specifically for joint support isn't in our data. Since we can't fully check all the ingredients for medication interactions, talk with your pharmacist before starting — especially if you take blood thinners or blood pressure medications.

Your doctor can advise whether this product fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Strong Joints, straight from the product label.

Brand Bare Performance Nutrition
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 336138
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Strong Joints by Bare Performance Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
IngredientAmount% DV
Hyaluronic Acid20 mg--
OptiMSM500 mg--
UC-II40 mg--
Total Collagen10 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Joint support formula

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

NSF Certified Sport BARE Standard

General Statements

30 Capsules in container

See for yourself

Strong Joints by Bare Performance Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Strong Joints by Bare Performance Nutrition

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hyaluronic Acid

No known
interactions
20 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

OptiMSM

500 mg per serving Form: Methylsulfonylmethane

UC-II

40 mg per serving Form: Cartilage
  • › Total Collagen

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Strong Joints by Bare Performance Nutrition Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Strong Joints. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Strong Joints, from the product label.

Bare Performance Nutrition

See all Bare Performance Nutrition products
Name
Bare Performance Nutrition
Pharmacist Counseling Corner

Strong Joints by Bare Performance Nutrition: Common Questions

Does Strong Joints by Bare Performance Nutrition interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Strong Joints. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Strong Joints contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my joint pain or arthritis?
The effectiveness of Strong Joints for joint pain or arthritis isn't established in the data we hold. The ingredients are thought to support connective tissue, but we don't have clinical evidence on file to confirm that. Ask your doctor whether it's worth trying for your specific situation.
Is hyaluronic acid safe to swallow?
Hyaluronic Acid is generally well tolerated by mouth and appears safe for most adults. That said, long-term safety of oral supplements isn't fully studied, and there isn't enough data to give it a full safety thumbs-up. If you have concerns, check with your doctor or pharmacist.
Can I take this if I'm pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data on file for any of the ingredients in Strong Joints. Talk with your doctor or pharmacist before taking this product — they can weigh the risks and benefits for your situation.
Does this product contain fillers?
Yes — Strong Joints includes inactive ingredients like hypromellose, microcrystalline cellulose, magnesium stearate, and silicon dioxide. These are standard capsule materials and binders; they're not active ingredients.
What is UC-II and why is it in here?
UC-II is a type of collagen peptide — a small, broken-down form of collagen meant to be easily absorbed. It's included because collagen is a main structural component of cartilage and joints, and makers believe it supports joint function. We don't have effectiveness data on file to confirm whether it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Strong Joints is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Strong Joints label
Go deeper

The Full Monographs Behind Strong Joints’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Strong Joints's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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