Interactions on record — worth a quick check against your medications. Based on 1 of 7 ingredients. Check your meds →
Dietary supplement

Super Pill No.3 Ingredients & Drug Interactions

by Ron Teeguarden's Dragon Herbs

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Super Pill No.3 is a dietary supplement by Ron Teeguarden's Dragon Herbs with 7 active ingredients. Its ingredients are commonly taken for depression and low mood, anxiety, pms symptoms.Based on those ingredients, 521 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saffron. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Pill No.3 by Ron Teeguarden's Dragon Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,500 mg) without saying how much of each component you get.

Super Pill No.3 contains seven active ingredients. Saffron is the one we have full data on — it's a spice used traditionally in herbal medicine and has been studied for conditions like nerve pain and memory support.

The other six ingredients are plant extracts: fermented Korean ginseng, ginsenoside Rg3, Chinese red salvia, tanshinone IIA, carthamus flower, and ligusticum root. We hold no monograph data on those five, so their roles in this blend and their effects aren't detailed in our files.

The capsule also contains inactive ingredients — pullulan polysaccharide, rice powder, bamboo extract, and calcium stearate — which are fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Saffron's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support general health and cardiovascular functioning.
  • We looked for evidence on: Hypertension, Hyperlipidemia, Heart health, Cholesterol management, Blood pressure support, Circulation.
  • The closest evidence on file: Saffron is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia (Natural Medicines).
  • Also on file: Saffron is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

Saffron in this product is rated possibly effective for chemotherapy-induced peripheral neuropathy (nerve pain from cancer treatment) and Alzheimer disease, based on clinical evidence. We don't have effectiveness ratings for the other six active ingredients, so we can't speak to what they may or may not do.

If you're considering this product for a specific health goal, ask your pharmacist or doctor whether the evidence supports its use for that purpose.

The evidence, ingredient by ingredient Saffron

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saffron extract is generally well tolerated when taken by mouth, though some people report gastrointestinal complaints, nausea, vomiting, and sedation. Rarely, anaphylaxis (a severe allergic reaction) can occur, and allergic reactions including occupational asthma have been reported from saffron exposure.

At higher doses, saffron has been associated with anxiety and mood changes in a small number of trial participants, though the link isn't certain. The safety data notes that saffron in supplement doses should be used with care — food amounts are likely safe, but high doses can be toxic.

Because there isn't enough reliable safety information on the other five ingredients we could not check, talk with your pharmacist about your individual situation before starting.

Side effects, ingredient by ingredient Saffron

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saffron.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 521 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your pharmacist if you take CNS depressants (sleeping pills, sedatives, anti-anxiety drugs), blood pressure medications, diabetes drugs, or caffeine supplements. Saffron can add to the effects of these drugs and change how they work in your body.

We couldn't check the other five active ingredients, so mention them to your pharmacist too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Super Pill No.3 is built around saffron, which has shown promise for nerve pain and memory but carries moderate interactions with sedatives, blood pressure drugs, and diabetes medications. Most of the other ingredients in this blend have no interaction data on file with us.

If you take any prescription or over-the-counter medications, check them against this product first — and talk with your pharmacist about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Pill No.3, straight from the product label.

Brand Ron Teeguarden's Dragon Herbs
Barcode (UPC) 679372001061
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 279251
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Pill No.3 by Ron Teeguarden's Dragon Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
20
UPC/BARCODE
679372001061
IngredientAmount% DV
Proprietary Blend1500 mg--
Saffron0 NP--
Korean Ginseng Root Extract, Powder, Fermented0 NP--
Ginsenoside Rg3 Extract, Powder0 NP--
Chinese Red Salvia Root Extract, Powder0 NP--
Tanshinone IIA Extract, Powder0 NP--
Carthamus Flower Extract, Powder0 NP--
Ligusticum Root Extract, Powder0 NP--

Other ingredients: Pullulan Polysaccharide, Rice, Powder, Bamboo Extract, Powder, Calcium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

If you are under medical care related to your cardiovascular health, consult your physician prior to using this product.

Warning: The use of this product will expose you to lead, a substance known to the state of California to cause birth defects or other reproductive harm.

Keep out of the reach of children.

Formula

Super Pill No.3 is a dietary supplement featuring tonic herbs and extraordinary nutraceuticals derived from those herbs - Tanshinone IIA and Ginsenoside Rg3 - that support general health and cardiovascular functioning. I also features premium grade Himalayan red saffron.

Pullulan caps - 100% natural, water-soluble polysaccharide produced through a fermentation process; vegetable origin; non-GMO; no starch, preservatives or chemical modifications; gluten free.

FDA Statement of Identity

Dietary Supplement

General Statements

Super Pill No.3 500 mg per capsule

Daily breathing in CA alone will result in lead exposure exceeding CA Prop 65 warning level for birth defects or reproductive harm.

Suggested/Recommended/Usage/Directions

Directions: Take 3 capsules, 2 times per day or as directed by a health care professional.

Formulation

Pullulan caps - 100% natural, water-soluble polysaccharide produced through a fermentation process; vegetable origin; non-GMO; no starch, preservatives or chemical modifications; gluten free.

The daily lead exposure from this product is lower than the amount allowed under FDA's standard for lead in bottled water.

See for yourself

Super Pill No.3 by Ron Teeguarden's Dragon Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Pill No.3 by Ron Teeguarden's Dragon Herbs

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1500 mg per serving
  • Saffron
  • › Korean Ginseng Root Extract, Powder, Fermented
  • › Ginsenoside Rg3 Extract, Powder
  • › Chinese Red Salvia Root Extract, Powder
  • › Tanshinone IIA Extract, Powder
  • › Carthamus Flower Extract, Powder
  • › Ligusticum Root Extract, Powder

Other (inactive) ingredients: Pullulan Polysaccharide, Rice, Powder, Bamboo Extract, Powder, Calcium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Pill No.3 by Ron Teeguarden's Dragon Herbs Drug Interactions

Want to check YOUR meds against Super Pill No.3?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
521Drugs
521 Moderate

Ingredients driving the most interactions

Saffron 521

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Pill No.3 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Saffron4 drug types · 521 drugs

Antidiabetes Drugs

Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.

Likelihood Possible Evidence D
Caffeine

Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Super Pill No.3, from the product label.

Ron Teeguarden's Dragon Herbs

See all Ron Teeguarden's Dragon Herbs products
Name
Ron Teeguarden's Dragon Herbs
Street Address
P.O. Box 361459
City
Los Angeles
State
CA
ZipCode
90036
Phone Number
(888) 558-6642
Web Address
www.dragonherbs.com
Pharmacist Counseling Corner

Super Pill No.3 by Ron Teeguarden's Dragon Herbs: Common Questions

Does Super Pill No.3 by Ron Teeguarden's Dragon Herbs interact with any medications?
Yes. Based on its ingredients, Super Pill No.3 has a known interaction with 521 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Pill No.3 contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure medication?
Saffron in this product can lower blood pressure on its own, so taking it with blood pressure meds could drop your pressure too far. Talk with your pharmacist or doctor before adding it — they may need to watch your blood pressure closely or adjust your dose.
What side effects might I get from saffron?
Most people tolerate saffron well, but some experience stomach upset, nausea, vomiting, and drowsiness. Rarely, allergic reactions including severe ones can happen. If you notice mood changes, anxiety, or agitation, stop and tell your pharmacist.
Is saffron safe to take while pregnant or breastfeeding?
The safety data we have says to avoid medicinal or supplement amounts of saffron during pregnancy because it may stimulate the uterus, and there isn't enough reliable information for breastfeeding. Talk with your doctor or midwife before using this product if you're pregnant or nursing.
Does this product actually work for what it claims?
Saffron is rated possibly effective for nerve pain from chemotherapy and for Alzheimer disease based on clinical research. We don't have effectiveness ratings for the other five ingredients in the blend, so we can't confirm what the full product does.
Why can't you tell me about the other ingredients?
We don't hold monograph data on Korean ginseng root extract, ginsenoside Rg3, Chinese red salvia, tanshinone IIA, carthamus flower, or ligusticum root, so we can't tell you how they interact with drugs or what side effects they might cause. Your pharmacist may have additional information on these.
What if I'm on a diabetes medication?
Saffron may increase your risk of low blood sugar (hypoglycemia) when combined with diabetes drugs, though the evidence depends on the form used. Check with your doctor or pharmacist before starting, as they may want to monitor your blood sugar levels.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Pill No.3 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Pill No.3 label
Sources

Sources & How We Checked

Super Pill No.3's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saffron 22 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Feo F, Martinez J, Martinez A, et al. Occupational allergy in saffron workers. Allergy 1997;52:633-41. PubMed
  5. Wuthrich B, Schmid-Grendelmeyer P, Lundberg M. Anaphylaxis to saffron. Allergy 1997;52:476-7. PubMed
  6. Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. Phytother Res 2005;19:148-51.
  7. Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasth
  8. Fatehi, M., Rashidabady, T., and Fatehi-Hassanabad, Z. Effects of Crocus sativus petals' extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. J Ethnopharmacol. 2003; PubMed
  9. Modaghegh, M. H., Shahabian, M., Esmaeili, H. A., Rajbai, O., and Hosseinzadeh, H. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. Phytomedicine. 2008;15(12):1032-1037. PubMed
  10. Imenshahidi, M., Hosseinzadeh, H., and Javadpour, Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. Phytother.Res 12-9-2009;
  11. Zhang, Y., Shoyama, Y., Sugiura, M., and Saito, H. Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performances in mice. Biol.Pharm Bull. 1994;17(2):217-221. PubMed
  12. Wuthrich, B., Schmid-Grendelmeyer, P., and Lundberg, M. Anaphylaxis to saffron. Allergy 1997;52(4):476-477. PubMed
  13. Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SSh, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi A. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and plac
  14. Kashani L, Eslatmanesh S, Saedi N, Niroomand N, Ebrahimi M, Hosseinian M, Foroughifar T, Salimi S, Akhondzadeh S. Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Ph PubMed
  15. Kianbakht S, Ghazavi A. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Phytother Res. 2011 Dec;25(12):1801-5. PubMed
  16. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. J C
  17. Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. Int J Impo PubMed
  18. Talaei A, Hassanpour Moghadam M, Sajadi Tabassi SA, Mohajeri SA. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: a randomized, double-blind, placebo-controlled, pilot clinical trial. J Affect Disord. 2 PubMed
  19. Azimi P, Ghiasvand R Feizi A, Hariri M, Abbasi B. Effects of cinnamon, cardamom, saffron, and ginger consumption on markers of glycemic control, lipid profile, oxidative stress, and inflammation in type 2 diabetes. Rev Diabet Stud. 2014 Fall-Winter;11(3-4
  20. Begas E, Bounitsi M, Kilindris T, et al. Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers. Food Chem Toxicol. 2019;130:32-43. PubMed
  21. Moravej Aleali A, Amani R, Shahbazian H, Namjooyan F, Latifi SM, Cheraghian B. The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabet
  22. Abbaszadeh-Mashkani S, Hoque SS, Banafshe HR, Ghaderi A. The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment. Phytother Res. 2021; PubMed

See these in context on the Saffron monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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