Sweet 'n Natural Stevia Leaf Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Sweet 'n Natural Stevia Leaf Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sweet 'n Natural Stevia Leaf Extract is a dietary supplement by Superior Source with 2 active ingredients. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sweet 'n Natural Stevia Leaf Extract by Superior Source
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HelloPharmacist Scorecard of Sweet 'n Natural Stevia Leaf Extract by Superior Source
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: stevia leaf extract, a sweetener derived from the stevia plant. The inactive ingredient is lactose, a common filler.
Does it work?
Not established
The evidence for stevia's effectiveness is limited. For diabetes, high blood pressure, and weight management—the main claims made about stevia—the data we hold shows insufficient reliable evidence to rate whether it actually works.
One small clinical trial found that a single 1000 mg dose reduced blood sugar spikes in people with type 2 diabetes when taken with a meal, but other research hasn't confirmed the same effect, so we can't say yet whether it's truly effective for blood sugar control.
How safe is it?
Well-documented data
Purified stevia in typical food amounts is generally recognized as safe. However, because this is a supplement dose (not food amounts) and whole-leaf stevia hasn't been well studied at high doses, use caution.
Most people who take stevia tolerate it well, though some report minor side effects like bloating, dizziness, headache, muscle aches, nausea, or numbness—most of these ease up after the first week. Allergic reactions are rare but have been reported.
There isn't enough safety data on file for pregnancy or breastfeeding.
Meds to double-check
Moderate interaction found
Check your medications before taking this product if you use lithium (mood stabilizer)—stevia may raise its levels. You should also double-check if you take blood pressure medications or diabetes drugs, where stevia might increase the effect.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you're looking for a stevia supplement and don't take lithium, blood pressure medication, or diabetes medication, this product is generally well tolerated. If you do take any of those, check with your pharmacist first.
Talk to us before starting any new supplement, especially if you're on prescription medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sweet 'n Natural Stevia Leaf Extract, straight from the product label.
| Brand | Superior Source |
|---|---|
| Barcode (UPC) | 076635400201 |
| Net contents | 9.73 oz.; 276 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jan 25, 2020 |
| DSLD ID | 212803 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sweet 'n Natural Stevia Leaf Extract by Superior Source, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 0 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Sugar | 1 Gram(s) | -- |
| Stevia leaf extract | 22.8 mg | -- |
Other ingredients: Lactose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Fresh look Same great taste!
Compare and decide: Herbal Aspartame free Saccharin free Sucralose free Sweet 'n Natural Yes Yes Yes Yes Equal No No Yes Yes Sweet 'n Low No Yes No Yes NutraSweet No No Yes Yes Splenda No Yes Yes No
For information & recipe ideas visit www.cvc4health.com
Formulation
Zero calorie powder
More recent medical research has shown promise in treating obesity and hypertension. Stevia has a negligible effect on blood glucose, even enhancing glucose tolerance; therefore, it is attractive as a natural sweetener to diabetics and others on carbohydrate-controlled diets.
Sweet ‘n Natural is Calorie free, Saccharin free, Aspartame free, and Sucralose free.
FDA Statement of Identity
Dietary Supplement
Formula
Stevia is a genus of about 240 species of herbs and shrubs in the sunflower family (Asteraceae), native to subtropical and tropical regions from western North America to South America. The species Stevia rebaudiana, commonly known as sweetleaf or Sugarleaf, or simply stevia, is widely grown for its sweet leaves. As a sweetener and sugar substitute, stevia’s taste has a slower onset and longer duration than that of sugar.
With its extracts having up to 300 times the sweetness of sugar, stevia has garnered attention with the rise in demand for low-carbohydrate, low sugar food alternatives. In a few countries, it has been available as a sweetener for decades or centuries; for example; stevia is widely used as a sweetener in Japan where it has been available for decades.
Suggested/Recommended/Usage/Directions
Directions: As an herbal dietary supplement, take 1/3 teaspoon into food or stir into beverages.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Equal is a registered trademark of Merisant Company, Chicago, IL Sweet’ n Low is a registered trademark of Cumberland Packing Corp., Brooklyn, NY NutraSweet is a registered trademark of NutraSweet Company, Chicago, IL Splenda is a registered trademark of McNeil-PPC. Inc., Fort Washington, PA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sweet 'n Natural Stevia Leaf Extract by Superior Source label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sweet 'n Natural Stevia Leaf Extract by Superior Source
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.876 Gram(s) Dosage formPowder Servings per container315 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Stevia leaf extract
Interacts with259 drugs
Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...
Stevia leaf extract monograph & interactionsOther (inactive) ingredients: Lactose. These complete the product’s ingredient list but are not active constituents.
Sweet 'n Natural Stevia Leaf Extract by Superior Source Drug Interactions
HelloPharmacist Interaction Report
Sweet 'n Natural Stevia Leaf Extract by Superior Source does interact with some medications, though the documented effects are mostly theoretical.
The most serious concern is with lithium (a mood-stabilizing medication). Stevia may reduce how your body clears lithium, potentially raising its levels to unsafe amounts.
This happens because stevia may work like a diuretic (a water pill), which can affect how your kidneys handle lithium.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to watch out if you take blood pressure medications. Stevia might lower blood pressure further, raising the risk of dizziness or fainting—though some research suggests it doesn't always have this effect.
Similarly, if you take diabetes medications, there's a theoretical risk that stevia could lower blood sugar too much, though the evidence is mixed.
Altogether, these interactions span 256 individual medications. Check your exact medications with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sweet 'n Natural Stevia Leaf Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sweet 'n Natural Stevia Leaf Extract interact with 259 drugs. Click any drug to see the details.
1 of the 2 ingredients in Sweet 'n Natural Stevia Leaf Extract interact with drugs. Each result below shows which ingredient is responsible. Stevia leaf extract
Lithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Sweet 'n Natural Stevia Leaf Extract — through 1 ingredient. Tap an ingredient for the detail:
Stevia Leaf ExtractLithium Moderate
Interaction Summary
Theoretically, stevia might decrease clearance and increase levels of lithium.
Read the full Stevia Leaf Extract + Lithium Carbonate (prescription Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sweet 'n Natural Stevia Leaf Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Stevia leaf extract
Lithium
Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.
Antidiabetes Drugs
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.
Antihypertensive Drugs
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.
Brand information
Manufacturer and brand details for Sweet 'n Natural Stevia Leaf Extract, from the product label.
Superior Source
See all Superior Source products- Name
- Superior Source Products
- City
- Los Angeles
- State
- CA
- ZipCode
- 90058
- Phone Number
- (800) 421-6175
Sweet 'n Natural Stevia Leaf Extract by Superior Source: Common Questions
Does Sweet 'n Natural Stevia Leaf Extract by Superior Source interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What side effects might I notice?
Will stevia actually help my blood sugar or weight?
Is this safe as a sweetener?
Can I take this while pregnant or breastfeeding?
What's in this powder besides the active ingredient?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sweet 'n Natural Stevia Leaf Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sweet 'n Natural Stevia Leaf Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sweet 'n Natural Stevia Leaf Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 10 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Stevia 10 references
- Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
- Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
- Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
- Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
- Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
- Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
- Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
- Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
- Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
- Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC