Tahitian Noni Ingredients & Drug Interactions
by Morinda
What is this page for?
First and foremost: checking Tahitian Noni against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tahitian Noni is a dietary supplement by Morinda with 4 active ingredients. Its ingredients are commonly taken for general wellness and energy, inflammation and joint pain, immune support.Based on those ingredients, 616 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Morinda citrifolia fruit nectar, Vaccinium corymbosum (Blueberry) juice concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Tahitian Noni by Morinda
Ask about any prescription or over-the-counter medication and we check it for interactions with Tahitian Noni by Morinda — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Tahitian Noni by Morinda
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Tahitian Noni contains 3 active ingredients. The primary ingredient is Morinda citrifolia fruit nectar—noni fruit—which has been used traditionally in the Pacific.
The product also includes Vaccinium corymbosum, or blueberry juice concentrate, and a proprietary blend of iridoids and phenolic compounds (plant-derived compounds believed to have antioxidant properties). The product is formulated as a liquid and includes grape juice concentrate and natural flavors as inactive ingredients.
Does it work?
Not established
The evidence supporting noni for any of its traditional or marketed uses—including asthma, atherosclerosis, athletic performance, burns, cancer, and cardiovascular disease—is insufficient to establish it as effective, according to the data we hold. Blueberry juice concentrate in this formula is rated possibly ineffective for high blood pressure and has insufficient evidence for cognitive decline, anxiety, athletic performance, cholesterol levels, and heart disease.
The product's actual benefits remain unproven in reliable clinical trials.
How safe is it?
Well-documented data
Noni is generally well tolerated in moderate amounts, though abdominal discomfort and nausea are the most common side effects when taken by mouth. Rare but serious liver injury (hepatotoxicity), including liver failure, has been reported in patients taking noni products, though whether noni itself or contaminants were responsible is unclear.
Because noni was traditionally used to cause abortion, the safety data advises against use during pregnancy. Blueberry juice concentrate is likely safe in pregnancy and is generally well tolerated overall, though freeze-dried blueberries in particular can cause constipation, diarrhea, nausea, or vomiting—in one trial, over a quarter of participants dropped out in the first week due to stomach upset.
The safety of high-dose blueberry extracts while breastfeeding is unknown.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist if you take blood pressure medications or potassium-regulating drugs (ACE inhibitors, ARBs, potassium-sparing diuretics), blood thinners like warfarin, the seizure medication phenytoin, diabetes medications, or certain pain relievers or anti-anxiety drugs. Noni's high potassium content and potential liver effects are the main concerns.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Tahitian Noni interacts with several important medication classes, particularly blood pressure drugs, potassium-regulating medications, blood thinners, and seizure medications. If you take any prescription drugs—especially for heart disease, blood pressure, or seizures—check with your pharmacist before adding this product.
The evidence for its effectiveness is insufficient, and liver injury is a rare but documented concern.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tahitian Noni, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tahitian Noni by Morinda, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 30 {Calories}, 15 {Calories} | -- |
| Total Carbohydrates | 6 Gram(s), 3 Gram(s) | 3%, 1% |
| Sugar | 4 Gram(s), 2 Gram(s) | -- |
| Proprietary Blend | 58 mg, 29 Gram(s) | -- |
| Iridoids/Phenolic Compounds | 30 mg, 15 mg | -- |
| Morinda citrifolia fruit nectar | 0 Not Present, 0 Not Present | -- |
| Vaccinium corymbosum (Blueberry) juice concentrate | 0 Not Present, 0 Not Present | -- |
Other ingredients: Vitis vinifera (Grape) Juice Concentrate, Natural Flavors
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
LIQUID DIETARY SUPPLEMENT
Brand IP Statement(s)
Tahitian Noni(R) Original(TM) Bioactive Supplement
Tahitian Noni(R) Original(TM) is the antidote. Its powerful bioactives enhance the immune system, boost energy naturally, support heart health, and more.
Get the facts at morinda.com
(C)2013 Morinda, Inc. All rights reserved.
Seals/Symbols
MORINDA(R)
Please recycle
General Statements
MAKE EVERY DAY HEALTHIER
Modern life is hazardous to your health.
Storage
Refrigerate after opening.
Precautions
Do not use if seal around cap is broken.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General
101825-13 1305080-US
Formula
30 mg iridoids & phenolic compounds per 60 ml
Suggested/Recommended/Usage/Directions
Suggested Use: Start by drinking 1 fluid ounce (30 ml) twice daily. Over time, adjust serving size based on personal needs. Shake well before using.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tahitian Noni by Morinda label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tahitian Noni by Morinda
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 fl. Oz. Dosage formLiquid Servings per container33 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Proprietary Blend
Iridoids/Phenolic Compounds
Other (inactive) ingredients: Vitis vinifera (Grape) Juice Concentrate, Natural Flavors. These complete the product’s ingredient list but are not active constituents.
Tahitian Noni by Morinda Drug Interactions
HelloPharmacist Interaction Report
Tahitian Noni by Morinda is a liquid with three active ingredients, and the noni fruit component carries documented interactions with a range of medications.
The most serious concern involves blood pressure drugs and potassium-regulating medications, where noni's high potassium content and blood-pressure-lowering properties create a moderate risk of dangerously low blood pressure or elevated potassium levels (hyperkalemia).
Read the full breakdown — every affected drug type, severity by severity
Noni may also reduce the effectiveness of blood thinners like warfarin and the seizure medication phenytoin, both moderate-severity interactions documented in case reports. Additionally, noni theoretically increases the risk of liver damage when combined with medications known to harm the liver (hepatotoxic drugs).
A minor interaction exists with ranitidine, where noni may increase its blood levels. Blueberry juice concentrate in this product carries minor interactions with diabetes medications and certain pain relievers and anti-anxiety drugs, though human studies have not confirmed clinically meaningful effects.
We could not check the proprietary blend's individual components or the iridoids and phenolic compounds listed separately. Altogether, these interactions span 599 individual medications.
Check your exact prescriptions with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tahitian Noni?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tahitian Noni interact with 616 drugs. Click any drug to see the details.
2 of the 4 ingredients in Tahitian Noni interact with drugs. Each result below shows which ingredient is responsible. Morinda citrifolia fruit nectar Vaccinium corymbosum (Blueberry) juice concentrate
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Tahitian Noni — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acarbose interactionVaccinium Corymbosum (blueberry) Juice ConcentrateAntidiabetes Drugs Minor
Interaction Summary
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Vaccinium Corymbosum (blueberry) Juice Concentrate + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Morinda Citrifolia Fruit Nectar + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Tahitian Noni — through 1 ingredient. Tap an ingredient for the detail:
Morinda Citrifolia Fruit NectarHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia Fruit Nectar + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tahitian Noni with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Morinda citrifolia fruit nectar
Ace Inhibitors (Aceis)
Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ACE inhibitors, which can also increase potassium levels.
Angiotensin Receptor Blockers (Arbs)
Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ARBs, which can also increase potassium levels.
Antihypertensive Drugs
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Preliminary clinical research suggests that drinking noni juice can reduce blood pressure in individuals with hypertension.
Hepatotoxic Drugs
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
There is concern that noni might cause hepatotoxicity in some patients. Advise patients against combining noni with potentially hepatotoxic drugs.
Phenytoin (Dilantin)
Theoretically, taking noni fruit juice concomitantly with phenytoin may lower phenytoin levels and increase the risk of seizures.
In one case report, an adult taking phenytoin for partial seizures experienced low serum phenytoin levels while taking noni juice 90-200 mL daily. Serum phenytoin levels increased after decreasing noni juice consumption; similarly, serum phenytoin levels decreased after increasing noni juice consumption. Some researchers believe noni juice may induce cytochrome P450 2C9 enzymes, which would decrease phenytoin levels, but this has not been well studied. Patients may need additional monitoring when starting or stopping noni juice supplementation.
Potassium-Sparing Diuretics
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with potassium-sparing diuretics, which can also increase potassium levels.
Warfarin (Coumadin)
Theoretically, taking noni juice concomitantly with warfarin might decrease the effectiveness of warfarin.
In one case, a 41-year-old patient stabilized on warfarin had a decreased international normalized ratio (INR) following consumption of a specific commercial noni juice product (Noni juice 4 Everything). While the patient was still taking noni juice, an increase in warfarin dose did not produce an increase in INR. However, it should be noted that this particular product contained extracts and derivatives from more than 115 components, many of which contained vitamin K. Furthermore, vitamin K was listed as a separate ingredient of the product, suggesting that the product was possibly fortified with vitamin K. It has not been verified that noni fruit alone contains a significant amount of vitamin K or interacts with warfarin.
Ranitidine (Zantac)
Taking noni fruit with ranitidine might increase the levels and clinical effects of ranitidine.
Clinical evidence shows that taking an aqueous extract of noni fruit 30 minutes prior to taking a single oral dose of ranitidine can increase the rate of absorption and plasma concentration of ranitidine.
Vaccinium corymbosum (Blueberry) juice concentrate
Antidiabetes Drugs
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.
Buspirone (Buspar)
Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.
Flurbiprofen (Ansaid, Others)
Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.
Brand information
Manufacturer and brand details for Tahitian Noni, from the product label.
Morinda
See all Morinda products- Name
- Morinda, Inc.
- Street Address
- 333 West River Park Drive
- City
- Provo
- State
- Utah
- ZipCode
- 84604
Tahitian Noni by Morinda: Common Questions
Does Tahitian Noni by Morinda interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Tahitian Noni if I'm pregnant?
Is it safe to breastfeed while taking this product?
What are the most common side effects?
Does this product actually work for the conditions it's marketed for?
Is there a risk of liver damage from this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Tahitian Noni is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tahitian Noni’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Noni
Interacts with 542 drugsNoni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits is limited. While moderate juice intake...
Read the full Noni monograph → Herb & supplement monographBlueberry
Interacts with 88 drugsBlueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...
Read the full Blueberry monograph →Sources & How We Checked
Tahitian Noni's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Noni 16 references
- Mueller BA, Scott MK, Sowinski KM, Prag KA. Noni juice (Morinda citrifolia): hidden potential for hyperkalemia? Am J Kidney Dis 2000;35:310-2. PubMed
- Millonig G, Stadlmann S, Vogel W. Herbal hepatotoxicity: acute hepatitis caused by a Noni preparation (Morinda citrifolia). Eur J Gastroenterol Hepatol 2005;17:445-7. PubMed
- Stadlbauer V, Fickert P, Lackner C, et al. Hepatotoxicity of NONI juice: report of two cases. World J Gastroenterol 2005;11:4758-60. PubMed
- Carr ME, Klotz J, Bergeron M. Coumadin resistance and the vitamin supplement "Noni". Am J Hematol 2004;77:103. PubMed
- Jensen CJ, Westendorf J, Wang MY, Wadsworth DP. Noni juice protects the liver. Eur J Gastroenterol Hepatol 2006;18:575-7. PubMed
- Yuce B, Gulberg V, Diebold J, Gerbes AL. Hepatitis induced by noni juice from morinda citrifolia: a rare cause of hepatotoxicity or the tip of the iceberg? Digestion 2006;73:167-70.
- Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
- Yu EL, Sivagnanam M, Ellis L, Huang JS. Acute hepatotoxicity after ingestion of Morinda citrifolia (noni berry) juice in a 14-year-old boy. J Pediatr Gastroenterol Nutr 2011;52:222-4.
- Stadlbauer V, Weiss S, Payer F, Stauber RE. Herbal does not at all mean innocuous: the sixth case of hepatotoxicity associated with morinda citrifolia (noni). Am J Gastroenterol 2008;103:2406-7. PubMed
- López-Cepero Andrada JM, Lerma Castilla S, Fernández Olvera MD, Amaya Vidal A. [Hepatotoxicity caused by a noni (Morinda citrifolia) preparation]. [Article in Spanish] Rev Esp Enferm Dig 2007;99:179-81.
- Nima S, Kasiwong S, Ridtitid W, et al. Gastrokinetic activity of Morinda citrifolia aqueous fruit extract and its possible mechanism of action in human and rat models. J Ethnopharmacol. 2012;142(2):354-61. PubMed
- Issell, B. F., Gotay, C. C., Pagano, I., and Franke, A. A. Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose. J.Diet.Suppl 2009;6(4):347-359. PubMed
- Palu AK, Santiago RA West B Kaluhiokalani N Jensen J. The Effects of Morillda citrifolia L. Noni on High Blood Pressure: A Mechanistic Investigation and Case Study. ACS SYMPOSIUM SERIES 993 2008;
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Bussmann RW, Hennig L, Giannis A, Ortwein J, Kutchan TM, Feng X. Anthraquinone Content in Noni (Morinda citrifolia L.). Evid Based Complement Alternat Med. 2013;2013:208378.
- Yu-Chan Kang, Ming-Hong Chen, Shung-Lon Lai. Potentially Unsafe Herb-drug Interactions Between a Commercial Product of Noni Juice and Phenytoin- A Case Report. Acta Neurol Taiwan. 2015 Jun;24(2):43-6.
Blueberry 7 references
- Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
- Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
- Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
- Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
- Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
- Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
- Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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