Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Tahitian Noni Ingredients & Drug Interactions

by Morinda

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Tahitian Noni is a dietary supplement by Morinda with 4 active ingredients. Its ingredients are commonly taken for general wellness and energy, inflammation and joint pain, immune support.Based on those ingredients, 616 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Morinda citrifolia fruit nectar, Vaccinium corymbosum (Blueberry) juice concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Tahitian Noni by Morinda

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (58 mg) without saying how much of each component you get.

Tahitian Noni contains 3 active ingredients. The primary ingredient is Morinda citrifolia fruit nectar—noni fruit—which has been used traditionally in the Pacific.

The product also includes Vaccinium corymbosum, or blueberry juice concentrate, and a proprietary blend of iridoids and phenolic compounds (plant-derived compounds believed to have antioxidant properties). The product is formulated as a liquid and includes grape juice concentrate and natural flavors as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: enhance immune system, boost energy, support heart health.
  • We looked for evidence on: Cardiovascular disease (CVD), Hyperlipidemia, Hypertension, Atherosclerosis, Athletic performance, Common cold — and 3 related terms.
  • The closest evidence on file: Blueberry is rated "Possibly Ineffective" for Hypertension (Natural Medicines).
  • Also on file: Noni is rated "Insufficient Reliable Evidence To Rate" for Atherosclerosis, Athletic performance, Cardiovascular disease (CVD), Common cold, and more.

The evidence supporting noni for any of its traditional or marketed uses—including asthma, atherosclerosis, athletic performance, burns, cancer, and cardiovascular disease—is insufficient to establish it as effective, according to the data we hold. Blueberry juice concentrate in this formula is rated possibly ineffective for high blood pressure and has insufficient evidence for cognitive decline, anxiety, athletic performance, cholesterol levels, and heart disease.

The product's actual benefits remain unproven in reliable clinical trials.

The evidence, ingredient by ingredient Noni Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Noni is generally well tolerated in moderate amounts, though abdominal discomfort and nausea are the most common side effects when taken by mouth. Rare but serious liver injury (hepatotoxicity), including liver failure, has been reported in patients taking noni products, though whether noni itself or contaminants were responsible is unclear.

Because noni was traditionally used to cause abortion, the safety data advises against use during pregnancy. Blueberry juice concentrate is likely safe in pregnancy and is generally well tolerated overall, though freeze-dried blueberries in particular can cause constipation, diarrhea, nausea, or vomiting—in one trial, over a quarter of participants dropped out in the first week due to stomach upset.

The safety of high-dose blueberry extracts while breastfeeding is unknown.

Side effects, ingredient by ingredient Noni Blueberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Noni, Blueberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 617 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take blood pressure medications or potassium-regulating drugs (ACE inhibitors, ARBs, potassium-sparing diuretics), blood thinners like warfarin, the seizure medication phenytoin, diabetes medications, or certain pain relievers or anti-anxiety drugs. Noni's high potassium content and potential liver effects are the main concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Tahitian Noni interacts with several important medication classes, particularly blood pressure drugs, potassium-regulating medications, blood thinners, and seizure medications. If you take any prescription drugs—especially for heart disease, blood pressure, or seizures—check with your pharmacist before adding this product.

The evidence for its effectiveness is insufficient, and liver injury is a rare but documented concern.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tahitian Noni, straight from the product label.

Brand Morinda
Net contents 1 Liter(s); 1.06 Quart(s)
Market status On market
Date entered into DSLD Dec 24, 2013
DSLD ID 27960
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tahitian Noni by Morinda, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 fl. Oz.
Maximum serving Sizes:
1 fl. Oz.
Servings per container
33
IngredientAmount% DV
Calories30 {Calories}, 15 {Calories}--
Total Carbohydrates6 Gram(s), 3 Gram(s)3%, 1%
Sugar4 Gram(s), 2 Gram(s)--
Proprietary Blend58 mg, 29 Gram(s)--
Iridoids/Phenolic Compounds30 mg, 15 mg--
Morinda citrifolia fruit nectar0 Not Present, 0 Not Present--
Vaccinium corymbosum (Blueberry) juice concentrate0 Not Present, 0 Not Present--

Other ingredients: Vitis vinifera (Grape) Juice Concentrate, Natural Flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

LIQUID DIETARY SUPPLEMENT

Brand IP Statement(s)

Tahitian Noni(R) Original(TM) Bioactive Supplement

Tahitian Noni(R) Original(TM) is the antidote. Its powerful bioactives enhance the immune system, boost energy naturally, support heart health, and more.

Get the facts at morinda.com

(C)2013 Morinda, Inc. All rights reserved.

Seals/Symbols

MORINDA(R)

Please recycle

General Statements

MAKE EVERY DAY HEALTHIER

Modern life is hazardous to your health.

Storage

Refrigerate after opening.

Precautions

Do not use if seal around cap is broken.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

101825-13 1305080-US

Formula

30 mg iridoids & phenolic compounds per 60 ml

Suggested/Recommended/Usage/Directions

Suggested Use: Start by drinking 1 fluid ounce (30 ml) twice daily. Over time, adjust serving size based on personal needs. Shake well before using.

See for yourself

Tahitian Noni by Morinda label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tahitian Noni by Morinda

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 fl. Oz. Dosage formLiquid Servings per container33 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

4 Gram(s) per serving

Iridoids/Phenolic Compounds

30 mg per serving

Other (inactive) ingredients: Vitis vinifera (Grape) Juice Concentrate, Natural Flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tahitian Noni by Morinda Drug Interactions

Want to check YOUR meds against Tahitian Noni?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
616Drugs
541 Moderate 75 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in Tahitian Noni with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Morinda citrifolia fruit nectar8 drug types · 542 drugs

Ace Inhibitors (Aceis)

Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ACE inhibitors, which can also increase potassium levels.

Likelihood Possible Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ARBs, which can also increase potassium levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Preliminary clinical research suggests that drinking noni juice can reduce blood pressure in individuals with hypertension.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
There is concern that noni might cause hepatotoxicity in some patients. Advise patients against combining noni with potentially hepatotoxic drugs.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Theoretically, taking noni fruit juice concomitantly with phenytoin may lower phenytoin levels and increase the risk of seizures.
In one case report, an adult taking phenytoin for partial seizures experienced low serum phenytoin levels while taking noni juice 90-200 mL daily. Serum phenytoin levels increased after decreasing noni juice consumption; similarly, serum phenytoin levels decreased after increasing noni juice consumption. Some researchers believe noni juice may induce cytochrome P450 2C9 enzymes, which would decrease phenytoin levels, but this has not been well studied. Patients may need additional monitoring when starting or stopping noni juice supplementation.

Likelihood Possible Evidence D
Potassium-Sparing Diuretics

Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with potassium-sparing diuretics, which can also increase potassium levels.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking noni juice concomitantly with warfarin might decrease the effectiveness of warfarin.
In one case, a 41-year-old patient stabilized on warfarin had a decreased international normalized ratio (INR) following consumption of a specific commercial noni juice product (Noni juice 4 Everything). While the patient was still taking noni juice, an increase in warfarin dose did not produce an increase in INR. However, it should be noted that this particular product contained extracts and derivatives from more than 115 components, many of which contained vitamin K. Furthermore, vitamin K was listed as a separate ingredient of the product, suggesting that the product was possibly fortified with vitamin K. It has not been verified that noni fruit alone contains a significant amount of vitamin K or interacts with warfarin.

Likelihood Possible Evidence D
Ranitidine (Zantac)

Taking noni fruit with ranitidine might increase the levels and clinical effects of ranitidine.
Clinical evidence shows that taking an aqueous extract of noni fruit 30 minutes prior to taking a single oral dose of ranitidine can increase the rate of absorption and plasma concentration of ranitidine.

Likelihood Possible Evidence B

Vaccinium corymbosum (Blueberry) juice concentrate3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Tahitian Noni, from the product label.

Morinda

See all Morinda products
Name
Morinda, Inc.
Street Address
333 West River Park Drive
City
Provo
State
Utah
ZipCode
84604
Pharmacist Counseling Corner

Tahitian Noni by Morinda: Common Questions

Does Tahitian Noni by Morinda interact with any medications?
Yes. Based on its ingredients, Tahitian Noni has a known interaction with 616 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tahitian Noni contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Tahitian Noni if I'm pregnant?
No. The safety data advises against it during pregnancy because noni was traditionally used to cause abortion. Talk with your doctor or pharmacist if you're pregnant or planning to become pregnant.
Is it safe to breastfeed while taking this product?
There isn't enough safety information about noni while breastfeeding. The blueberry concentrate is likely safe, but the safety of high-dose blueberry extracts is unknown. Talk with your doctor or pharmacist about whether it's right for you.
What are the most common side effects?
Abdominal discomfort and nausea are the most common side effects from noni. Blueberry juice concentrate can cause constipation, diarrhea, nausea, or vomiting, especially in freeze-dried form—one trial saw over a quarter of participants drop out in the first week due to stomach upset.
Does this product actually work for the conditions it's marketed for?
The evidence we hold is insufficient to establish noni as effective for asthma, atherosclerosis, athletic performance, burns, cancer, or cardiovascular disease. Blueberry is rated possibly ineffective for high blood pressure and insufficient for other uses listed.
Is there a risk of liver damage from this product?
Rare but serious liver injury (hepatotoxicity) has been reported in patients taking noni products, though it's unclear whether noni itself or contaminants in the product caused it. Avoid combining noni with medications known to damage the liver.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tahitian Noni is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tahitian Noni label
Sources

Sources & How We Checked

Tahitian Noni's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Noni 16 references
  1. Mueller BA, Scott MK, Sowinski KM, Prag KA. Noni juice (Morinda citrifolia): hidden potential for hyperkalemia? Am J Kidney Dis 2000;35:310-2. PubMed
  2. Millonig G, Stadlmann S, Vogel W. Herbal hepatotoxicity: acute hepatitis caused by a Noni preparation (Morinda citrifolia). Eur J Gastroenterol Hepatol 2005;17:445-7. PubMed
  3. Stadlbauer V, Fickert P, Lackner C, et al. Hepatotoxicity of NONI juice: report of two cases. World J Gastroenterol 2005;11:4758-60. PubMed
  4. Carr ME, Klotz J, Bergeron M. Coumadin resistance and the vitamin supplement "Noni". Am J Hematol 2004;77:103. PubMed
  5. Jensen CJ, Westendorf J, Wang MY, Wadsworth DP. Noni juice protects the liver. Eur J Gastroenterol Hepatol 2006;18:575-7. PubMed
  6. Yuce B, Gulberg V, Diebold J, Gerbes AL. Hepatitis induced by noni juice from morinda citrifolia: a rare cause of hepatotoxicity or the tip of the iceberg? Digestion 2006;73:167-70.
  7. Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
  8. Yu EL, Sivagnanam M, Ellis L, Huang JS. Acute hepatotoxicity after ingestion of Morinda citrifolia (noni berry) juice in a 14-year-old boy. J Pediatr Gastroenterol Nutr 2011;52:222-4.
  9. Stadlbauer V, Weiss S, Payer F, Stauber RE. Herbal does not at all mean innocuous: the sixth case of hepatotoxicity associated with morinda citrifolia (noni). Am J Gastroenterol 2008;103:2406-7. PubMed
  10. López-Cepero Andrada JM, Lerma Castilla S, Fernández Olvera MD, Amaya Vidal A. [Hepatotoxicity caused by a noni (Morinda citrifolia) preparation]. [Article in Spanish] Rev Esp Enferm Dig 2007;99:179-81.
  11. Nima S, Kasiwong S, Ridtitid W, et al. Gastrokinetic activity of Morinda citrifolia aqueous fruit extract and its possible mechanism of action in human and rat models. J Ethnopharmacol. 2012;142(2):354-61. PubMed
  12. Issell, B. F., Gotay, C. C., Pagano, I., and Franke, A. A. Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose. J.Diet.Suppl 2009;6(4):347-359. PubMed
  13. Palu AK, Santiago RA West B Kaluhiokalani N Jensen J. The Effects of Morillda citrifolia L. Noni on High Blood Pressure: A Mechanistic Investigation and Case Study. ACS SYMPOSIUM SERIES 993 2008;
  14. Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
  15. Bussmann RW, Hennig L, Giannis A, Ortwein J, Kutchan TM, Feng X. Anthraquinone Content in Noni (Morinda citrifolia L.). Evid Based Complement Alternat Med. 2013;2013:208378.
  16. Yu-Chan Kang, Ming-Hong Chen, Shung-Lon Lai. Potentially Unsafe Herb-drug Interactions Between a Commercial Product of Noni Juice and Phenytoin- A Case Report. Acta Neurol Taiwan. 2015 Jun;24(2):43-6.

See these in context on the Noni monograph →

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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