TruAge Pure Ingredients & Drug Interactions
by Morinda
What is this page for?
First and foremost: checking TruAge Pure against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
TruAge Pure is a dietary supplement by Morinda with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,078 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Morinda citrifolia (noni) fruit puree. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against TruAge Pure by Morinda
Ask about any prescription or over-the-counter medication and we check it for interactions with TruAge Pure by Morinda — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of TruAge Pure by Morinda
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
TruAge Pure is a liquid blend with 3 active ingredients: noni fruit puree and noni leaf tea — both from the Morinda citrifolia plant — plus a proprietary blend of iridoids and phenolic compounds. Noni has been used traditionally for various health purposes, though the specific role of each component in this product isn't detailed in the available information.
There are no inactive ingredients (fillers, binders, or capsule materials) listed.
Does it work?
Not established
The evidence for noni in this product hasn't been established for any of the conditions we have data on — asthma, atherosclerosis, athletic performance, burns, cancer, and cardiovascular disease all show insufficient reliable evidence. If you're considering this product for another purpose, that information isn't on file for us.
How safe is it?
Well-documented data
Noni is generally well tolerated in moderate amounts, though serious side effects are rare. The most common complaints are abdominal discomfort and nausea.
Rare but serious cases of liver injury have been linked to noni products, though it's unclear whether noni itself or contaminants caused the damage. High potassium content is also a concern, especially if you have kidney problems or take medications that affect potassium levels.
Do not take this product during pregnancy — noni has been traditionally used to cause abortion, and there isn't enough safety information otherwise. There's no data on file about safety during breastfeeding, so talk with your doctor or pharmacist about that.
Meds to double-check
Moderate interaction found
Double-check this product before taking it if you're on warfarin or other blood thinners; ACE inhibitors, ARBs, or potassium-sparing diuretics for blood pressure; blood pressure-lowering drugs; ranitidine (Zantac); phenytoin (Dilantin) for seizures; or any medication that can damage the liver.
The bottom line
Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This is a noni-based product with documented interactions with blood thinners, blood pressure drugs, seizure medications, and others. If you take any prescription medications — especially for the heart, blood pressure, seizures, or clotting — check with us or your pharmacist before starting.
Pregnant women should avoid it entirely.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about TruAge Pure, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for TruAge Pure by Morinda, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 {Calories}, 5 {Calories} | -- |
| Total Carbohydrates | 5 Gram(s), 1 Gram(s) | 2%, 1% |
| Dietary Fiber | 3 Gram(s), 1 Gram(s) | 12%, 3% |
| Proprietary Blend | 30 mL, 15 mL | -- |
| Iridoids/Phenolic Compounds | 72 mg, 18 mg | -- |
| Morinda citrifolia (noni) fruit puree | 0 Not Present, 0 Not Present | -- |
| Morinda citrifolia (noni) leaf tea | 0 Not Present, 0 Not Present | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
BOOST YOUR JUICE Pure is stripped down to the essential noni iridoids and nutrients. Just one ounce adds a potent iridoid kick to your favorite food or drink. It's straight-from-the-source support for your heart, joints, and immune system.
CONCENTRATE
Suggested/Recommended/Usage/Directions
Suggested Use: One tablespoon (15 ml) contains 18 mg of iridoids. Use as needed.
General
202962 1302031-US
Brand IP Statement(s)
(C)2013 Morinda, Inc.
Seals/Symbols
MORINDA(R)
please recycle
Formula
72MG IRIDOIDS & PHENOLIC COMPOUNDS PER 60 ML CONCENTRATE made from Morinda Citrifolia
FDA Statement of Identity
DIETARY SUPPLEMENT
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
TruAge Pure by Morinda label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in TruAge Pure by Morinda
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tbsp Dosage formLiquid Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProprietary Blend
Iridoids/Phenolic Compounds
TruAge Pure by Morinda Drug Interactions
HelloPharmacist Interaction Report
TruAge Pure by Morinda contains noni fruit and leaf, both of which interact with a number of medications.
The most serious concern is with blood thinners (anticoagulants) like warfarin — noni may reduce their effectiveness, which could raise your clot risk. There's also a risk of dangerously high potassium levels if you're on blood pressure medications that preserve potassium, including ACE inhibitors, ARBs, or potassium-sparing diuretics.
Read the full breakdown — every affected drug type, severity by severity
Noni can lower blood pressure on its own, so combining it with blood pressure-lowering drugs increases the risk of dizziness or fainting. It may also boost levels of the heartburn medication ranitidine (Zantac), and it theoretically raises the risk of liver damage if you're taking other drugs that can harm the liver.
Additionally, noni may reduce levels of the seizure medication phenytoin (Dilantin), putting you at risk of breakthrough seizures.
Altogether, these interactions span 526 individual medications. We could not check Iridoids/Phenolic Compounds — we hold no data for that ingredient.
Please run your exact medications through the checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against TruAge Pure?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in TruAge Pure interact with 2,078 drugs. Click any drug to see the details.
2 of the 4 ingredients in TruAge Pure interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Morinda citrifolia (noni) fruit puree
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + 6-mercaptopurine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Abacavir Sulfate, Dolutegravir, Lamivudine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Abacavir, Lamivudine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Abiraterone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Abiraterone Acetate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acebutolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Aspirin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Aspirin, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Butalbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Butalbital, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Butalbital, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Butalbital, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Butalbital, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Caffeine, Codeine, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Caffeine, Dihydrocodeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Caffeine, Isometheptene interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Caffeine, Pyrilamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with TruAge Pure — through 2 ingredients. Tap an ingredient for the detail:
Morinda Citrifolia (noni) Leaf TeaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Morinda Citrifolia (noni) Leaf Tea + Acetaminophen, Chlorpheniramine, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in TruAge Pure with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Morinda citrifolia (noni) fruit puree
Ace Inhibitors (Aceis)
Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ACE inhibitors, which can also increase potassium levels.
Angiotensin Receptor Blockers (Arbs)
Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ARBs, which can also increase potassium levels.
Antihypertensive Drugs
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Preliminary clinical research suggests that drinking noni juice can reduce blood pressure in individuals with hypertension.
Hepatotoxic Drugs
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
There is concern that noni might cause hepatotoxicity in some patients. Advise patients against combining noni with potentially hepatotoxic drugs.
Phenytoin (Dilantin)
Theoretically, taking noni fruit juice concomitantly with phenytoin may lower phenytoin levels and increase the risk of seizures.
In one case report, an adult taking phenytoin for partial seizures experienced low serum phenytoin levels while taking noni juice 90-200 mL daily. Serum phenytoin levels increased after decreasing noni juice consumption; similarly, serum phenytoin levels decreased after increasing noni juice consumption. Some researchers believe noni juice may induce cytochrome P450 2C9 enzymes, which would decrease phenytoin levels, but this has not been well studied. Patients may need additional monitoring when starting or stopping noni juice supplementation.
Potassium-Sparing Diuretics
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with potassium-sparing diuretics, which can also increase potassium levels.
Warfarin (Coumadin)
Theoretically, taking noni juice concomitantly with warfarin might decrease the effectiveness of warfarin.
In one case, a 41-year-old patient stabilized on warfarin had a decreased international normalized ratio (INR) following consumption of a specific commercial noni juice product (Noni juice 4 Everything). While the patient was still taking noni juice, an increase in warfarin dose did not produce an increase in INR. However, it should be noted that this particular product contained extracts and derivatives from more than 115 components, many of which contained vitamin K. Furthermore, vitamin K was listed as a separate ingredient of the product, suggesting that the product was possibly fortified with vitamin K. It has not been verified that noni fruit alone contains a significant amount of vitamin K or interacts with warfarin.
Ranitidine (Zantac)
Taking noni fruit with ranitidine might increase the levels and clinical effects of ranitidine.
Clinical evidence shows that taking an aqueous extract of noni fruit 30 minutes prior to taking a single oral dose of ranitidine can increase the rate of absorption and plasma concentration of ranitidine.
Brand information
Manufacturer and brand details for TruAge Pure, from the product label.
Morinda
See all Morinda products- Name
- Morinda, Inc.
- Street Address
- 333 West River Park Drive
- City
- Provo
- State
- Utah
- ZipCode
- 84604
TruAge Pure by Morinda: Common Questions
Does TruAge Pure by Morinda interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take TruAge Pure while pregnant?
What are the common side effects?
Does this product actually work for anything?
Is there enough information about safety while breastfeeding?
Why does this product interact with so many drugs?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if TruAge Pure is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind TruAge Pure’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographNoni
Interacts with 542 drugsNoni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits is limited. While moderate juice intake...
Read the full Noni monograph →Sources & How We Checked
TruAge Pure's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 34 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Noni 16 references
- Mueller BA, Scott MK, Sowinski KM, Prag KA. Noni juice (Morinda citrifolia): hidden potential for hyperkalemia? Am J Kidney Dis 2000;35:310-2. PubMed
- Millonig G, Stadlmann S, Vogel W. Herbal hepatotoxicity: acute hepatitis caused by a Noni preparation (Morinda citrifolia). Eur J Gastroenterol Hepatol 2005;17:445-7. PubMed
- Stadlbauer V, Fickert P, Lackner C, et al. Hepatotoxicity of NONI juice: report of two cases. World J Gastroenterol 2005;11:4758-60. PubMed
- Carr ME, Klotz J, Bergeron M. Coumadin resistance and the vitamin supplement "Noni". Am J Hematol 2004;77:103. PubMed
- Jensen CJ, Westendorf J, Wang MY, Wadsworth DP. Noni juice protects the liver. Eur J Gastroenterol Hepatol 2006;18:575-7. PubMed
- Yuce B, Gulberg V, Diebold J, Gerbes AL. Hepatitis induced by noni juice from morinda citrifolia: a rare cause of hepatotoxicity or the tip of the iceberg? Digestion 2006;73:167-70.
- Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
- Yu EL, Sivagnanam M, Ellis L, Huang JS. Acute hepatotoxicity after ingestion of Morinda citrifolia (noni berry) juice in a 14-year-old boy. J Pediatr Gastroenterol Nutr 2011;52:222-4.
- Stadlbauer V, Weiss S, Payer F, Stauber RE. Herbal does not at all mean innocuous: the sixth case of hepatotoxicity associated with morinda citrifolia (noni). Am J Gastroenterol 2008;103:2406-7. PubMed
- López-Cepero Andrada JM, Lerma Castilla S, Fernández Olvera MD, Amaya Vidal A. [Hepatotoxicity caused by a noni (Morinda citrifolia) preparation]. [Article in Spanish] Rev Esp Enferm Dig 2007;99:179-81.
- Nima S, Kasiwong S, Ridtitid W, et al. Gastrokinetic activity of Morinda citrifolia aqueous fruit extract and its possible mechanism of action in human and rat models. J Ethnopharmacol. 2012;142(2):354-61. PubMed
- Issell, B. F., Gotay, C. C., Pagano, I., and Franke, A. A. Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose. J.Diet.Suppl 2009;6(4):347-359. PubMed
- Palu AK, Santiago RA West B Kaluhiokalani N Jensen J. The Effects of Morillda citrifolia L. Noni on High Blood Pressure: A Mechanistic Investigation and Case Study. ACS SYMPOSIUM SERIES 993 2008;
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Bussmann RW, Hennig L, Giannis A, Ortwein J, Kutchan TM, Feng X. Anthraquinone Content in Noni (Morinda citrifolia L.). Evid Based Complement Alternat Med. 2013;2013:208378.
- Yu-Chan Kang, Ming-Hong Chen, Shung-Lon Lai. Potentially Unsafe Herb-drug Interactions Between a Commercial Product of Noni Juice and Phenytoin- A Case Report. Acta Neurol Taiwan. 2015 Jun;24(2):43-6.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC