Tart Cherry Ultramax Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Tart Cherry Ultramax against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tart Cherry Ultramax is a dietary supplement by Everyday Health with 3 active ingredients. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 728 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Celery Seed Extract, Apple Cider Vinegar Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Tart Cherry Ultramax by Everyday Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Tart Cherry Ultramax by Everyday Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Tart Cherry Ultramax by Everyday Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Tart Cherry Ultramax contains three active ingredients: Apple Cider Vinegar Extract, Celery Seed Extract, and Tart Cherry extract. The product also includes gelatin and magnesium stearate as inactive ingredients — these are the capsule material and a processing aid, not active components.
Does it work?
Not established
The evidence we hold rates the effectiveness of these ingredients as follows: Tart Cherry extract is possibly effective for athletic performance; the data doesn't establish reliable evidence for the other claimed uses like ADHD, cognitive function, or exercise-induced muscle soreness. Apple Cider Vinegar Extract and Celery Seed Extract both have insufficient evidence for their common uses — acne, depression, anxiety, diabetes, and others are not established in the data we hold.
If you're considering this product for a specific reason, it's worth talking through whether the evidence matches your goal.
How safe is it?
Well-documented data
Apple Cider Vinegar Extract is well tolerated in food amounts and short-term medicinal use, but larger doses or long-term use carry risks — chronic high doses have been linked to low potassium, elevated renin levels, and osteoporosis in rare cases. The facts emphasize avoiding large medicinal or unpasteurized amounts without medical approval.
Celery Seed Extract is generally well tolerated orally, but allergy is a concern — symptoms can range from oral itching and burning to serious reactions like anaphylactic shock in sensitive people. Tart Cherry extract is generally well tolerated as whole fruit or concentrate, though concentrated supplements are less studied; reported side effects are mostly gastrointestinal — abdominal pain, loose stools, and upset stomach — and occurred in a meaningful portion of trial participants (about 29% of children in one study reported abdominal pain).
Meds to double-check
Moderate interaction found
Check your medications if you take digoxin (heart medication) — Moderate risk of increased toxicity. If you're on water pills (diuretics), insulin, diabetes drugs, blood thinners, thyroid medication (levothyroxine), lithium, antidepressants like venlafaxine, or blood pressure medications, these also carry documented Moderate-severity interactions with the ingredients in this product.
Use the medication checker below with your exact prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take digoxin, a water pill, insulin, a diabetes medication, a blood thinner, levothyroxine, lithium, or venlafaxine, run this product and your exact medications through the checker on this page before you start. If you have a celery allergy, avoid this product.
Talk to your pharmacist or doctor about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tart Cherry Ultramax, straight from the product label.
| Brand | Everyday Health |
|---|---|
| Barcode (UPC) | 9421905900980 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2024 |
| DSLD ID | 306125 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tart Cherry Ultramax by Everyday Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Apple Cider Vinegar Extract | 100 mg | -- |
| Celery Seed Extract | 180 mg | -- |
| Tart Cherry extract | 220 mg | -- |
Other ingredients: Gelatin, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store cool and dry
Precautions
Keep out of reach of children
Caution: If you suffer from any health problems or on medications consult a physician before using.
Formulation
Healthy joints & uric acid management
Formula
Tart cherry + ACV + celery seed
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 1 capsule up to 3 times per day, until symptoms are managed, then lower to a 1 capsule per day maintenance dose. Or as advised by your doctor.
Seals/Symbols
GMP Good Manufacturing Practice
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tart Cherry Ultramax by Everyday Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tart Cherry Ultramax by Everyday Health
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Apple Cider Vinegar Extract
Interacts with162 drugs
Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...
Apple Cider Vinegar Extract monograph & interactionsCelery Seed Extract
Interacts with651 drugs
Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort....
Celery Seed Extract monograph & interactionsTart Cherry extract
No knowninteractions
Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, jo...
Tart Cherry extract monograph & interactionsOther (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Tart Cherry Ultramax by Everyday Health Drug Interactions
HelloPharmacist Interaction Report
Tart Cherry Ultramax by Everyday Health contains three active ingredients, and two of them have documented interactions with medications.
The most serious concern involves Apple Cider Vinegar Extract and digoxin (Lanoxin), a heart medication — concomitant use may increase the risk of heart toxicity because the vinegar can lower your potassium levels, which makes digoxin more dangerous.
Read the full breakdown — every affected drug type, severity by severity
Apple Cider Vinegar Extract also interacts with water pills (diuretics), insulin, and diabetes medications. With diuretics and insulin, the risk is low potassium (hypokalemia); with diabetes drugs, there's a theoretical risk of low blood sugar (hypoglycemia).
Celery Seed Extract carries Moderate-severity interactions with blood thinners (anticoagulant/antiplatelet drugs), which may increase bleeding risk, and with levothyroxine (Synthroid), where the celery may reduce how well the thyroid medication works — a few cases of hypothyroidism have been reported in people stabilized on levothyroxine who then started celery seed tablets. Celery Seed also interacts with lithium, certain antidepressants like venlafaxine (Effexor), blood pressure medications, and several other drug classes.
Tart Cherry Extract has no documented interactions in our data. Altogether, these interactions span 724 individual medications.
Use the medication checker below with your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tart Cherry Ultramax?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tart Cherry Ultramax interact with 728 drugs. Click any drug to see the details.
2 of the 3 ingredients in Tart Cherry Ultramax interact with drugs. Each result below shows which ingredient is responsible. Celery Seed Extract Apple Cider Vinegar Extract
AbciximabReoPro
How Abciximab interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery Seed Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery Seed Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Read the full Celery Seed Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery Seed Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAnticoagulant/antiplatelet Drugs, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Celery Seed Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Tart Cherry Ultramax — through 2 ingredients. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Caffeine, Pyrilamine interactionApple Cider Vinegar ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractPhotosensitizing Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractAcetaminophen (tylenol, Others), Photosensitizing Drugs +1 Moderate
Interaction Summary
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Tart Cherry Ultramax — through 1 ingredient. Tap an ingredient for the detail:
Celery Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Acetaminophen (tylenol, Others) +1 Moderate
Interaction Summary
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
Read the full Celery Seed Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tart Cherry Ultramax with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Celery Seed Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, celery root might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Celery root contains the constituents falcarinol and falcarindiol. Laboratory research suggests that these constituents can inhibit platelet aggregation. This effect has not been reported in humans.
Antihypertensive Drugs
Theoretically, celery seed extract might have additive effects with antihypertensive drugs.
Clinical research suggests that taking celery seed extract may reduce daytime systolic blood pressure by about 12 mmHg compared to less than 1 mmHg with placebo.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, celery might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggests that constituents of celery can inhibit CYP1A2. This effect has not been reported in humans.
Levothyroxine (Synthroid, Others)
Theoretically, celery seed might decrease the effects of levothyroxine.
Several cases of hypothyroidism with low T4 levels have been reported in people who were previously stabilized on levothyroxine and then started taking celery seed tablets. They presented with symptoms such as lethargy, bloating, and dry skin, and recovered when celery seed was stopped. However, celery stem and leaf has been associated with case reports of hyperthyroidism in patients with no pre-existing thyroid disorders.
Lithium
Theoretically, celery might reduce excretion and increase levels of lithium due to potential diuretic effects.
Celery is thought to have diuretic properties. However, this effect has not been confirmed in humans.
Venlafaxine (Effexor)
Theoretically, celery root extract might increase blood levels of venlafaxine.
There is one case report of a patient who experienced medication-induced bipolar disorder after beginning to take celery root extract 1000 mg daily along with venlafaxine 75 mg and St. John's wort 600 mg daily. Symptoms included confusion, speech abnormalities, manic affect, and visual hallucinations. The plasma level of venlafaxine was 476.8 ng/mL (normal range 195-400 ng/mL). It is theorized that celery root increased venlafaxine levels by inhibiting cytochrome P450 2D6.
Acetaminophen (Tylenol, Others)
Theoretically, celery juice might increase the effects and side effects of acetaminophen.
Animal research suggests that concomitant use of celery juice plus acetaminophen prolongs the effects of acetaminophen. This effect has been attributed to a decrease in hepatic cytochrome P450 activity. However, other animal research shows that pretreatment with celery root extract protects against acetaminophen-induced acute liver failure. These effects have not been reported in humans.
Photosensitizing Drugs
Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Laboratory research shows that celery contains photosensitizing agents such as phenols and psoralens.
Apple Cider Vinegar Extract
Digoxin (Lanoxin)
Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.
Diuretic Drugs
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.
Insulin
Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.
Antidiabetes Drugs
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.
Brand information
Manufacturer and brand details for Tart Cherry Ultramax, from the product label.
Everyday Health
See all Everyday Health products- Name
- Everyday Health Ltd
- Street Address
- 1 Kingsford Smith Drive
- City
- Rangiora
- Phone Number
- 0800 773 766
- Web Address
- www.everydayhealth.nz
Tart Cherry Ultramax by Everyday Health: Common Questions
Does Tart Cherry Ultramax by Everyday Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does tart cherry actually work for muscle soreness from exercise?
Is this safe if I'm pregnant or breastfeeding?
What side effects might I experience?
Can I take this if I have a celery allergy?
Is there any data on how long I can safely take this?
Does it matter if I take this with food?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tart Cherry Ultramax’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Apple Cider Vinegar
Interacts with 162 drugsApple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...
Read the full Apple Cider Vinegar monograph → Herb & supplement monographCelery
Interacts with 651 drugsCelery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort. Human evidence for these supplement use...
Read the full Celery monograph → Herb & supplement monographSour Cherry
Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, joint and gout symptoms, and sleep. Early...
Read the full Sour Cherry monograph →Sources & How We Checked
Tart Cherry Ultramax's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 63 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Apple Cider Vinegar 11 references
- Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
- Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
- Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
- Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
- Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
- Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
- Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
- Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
- Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
- Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
- Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro
Celery 48 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
- Moses, G. Thyroxine interacts with celery seed tablets? Australian Prescriber 2001;24:6-7. DOI
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
- Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water". Cutis 2002;70(1):29-30.
- Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
- Rueff, F., Eberlein-Konig, B., and Przybilla, B. Oral hyposensitization with celery juice. Allergy 2001;56(1):82-83. PubMed
- Lombaert, G. A., Siemens, K. H., Pellaers, P., Mankotia, M., and Ng, W. Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. J AOAC Int 2001;84(4):1135-1143. DOI
- Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B., Luttkopf, D., Pompei, C., Wangorsch, A., Kastner, M., and Vieths, S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy PubMed
- Hoerler, S. and Ukiwe, J. Laryngeal edema from celery allergic reaction. Am.J.Emerg.Med. 1992;10(6):613. PubMed
- DeLeo, V. A. Photocontact dermatitis. Dermatol Ther 2004;17(4):279-288. PubMed
- Groot, B. J., Belinfante-van Gelder, M. E., and Jans, H. W. [An epidemic of dermatitis caused by blanched celery]. Ned.Tijdschr.Geneeskd. 6-20-1992;136(25):1210-1213.
- Erdmann, S. M., Sachs, B., Schmidt, A., Merk, H. F., Scheiner, O., Moll-Slodowy, S., Sauer, I., Kwiecien, R., Maderegger, B., and Hoffmann-Sommergruber, K. In vitro analysis of birch-pollen-associated food allergy by use of recombinant allergens in the b
- Jeanmougin, M., Varroud-Vial, C., and Dubertret, L. [Phototoxic side-effect following celery ingestion during puvatherapy]. Ann.Dermatol Venereol 2005;132(6-7 Pt 1):566-567.
- Christensen, L. P. and Brandt, K. Bioactive polyacetylenes in food plants of the Apiaceae family: occurrence, bioactivity and analysis. J Pharm.Biomed.Anal. 6-7-2006;41(3):683-693. PubMed
- Gorgus, E., Lohr, C., Raquet, N., Guth, S., and Schrenk, D. Limettin and furocoumarins in beverages containing citrus juices or extracts. Food Chem.Toxicol. 2010;48(1):93-98. PubMed
- Maso, M. J., Ruszkowski, A. M., Bauerle, J., DeLeo, V. A., and Gasparro, F. P. Celery phytophotodermatitis in a chef. Arch.Dermatol. 1991;127(6):912-913. DOI
- Ljunggren, B. Severe phototoxic burn following celery ingestion. Arch.Dermatol. 1990;126(10):1334-1336. DOI
- Held, J. L. Phytophotodermatitis. Am Fam.Physician 1989;39(4):143-146.
- Silverstein, S. R., Frommer, D. A., Dobozin, B., and Rosen, P. Celery-dependent exercise-induced anaphylaxis. J.Emerg.Med. 1986;4(3):195-199. PubMed
- Rose, M. H. and Altman, L. C. Anaphylaxis after ingestion of raw celery. Ann.Allergy 1985;54(2):166.
- Forsbeck, M. and Ros, A. M. Anaphylactoid reaction to celery. Contact Dermatitis 1979;5(3):191. PubMed
- DeChamp, C., Michel, J., Deviller, P., and Perrin, L. F. [Anaphylactic shock to celery and sensitization to ragweed and mugwort. Crossed or concomitant allergy?]. Presse Med. 3-31-1984;13(14):871-874.
- Johansson, S. G., Dannaeus, A., and Lilja, G. The relevance of anti-food antibodies for the diagnosis of food allergy. Ann.Allergy 1984;53(6 Pt 2):665-672.
- Beier, R. C., Ivie, G. W., Oertli, E. H., and Holt, D. L. HPLC analysis of linear furocoumarins (psoralens) in healthy celery (Apium graveolens). Food Chem.Toxicol. 1983;21(2):163-165. PubMed
- Kidd, J. M., III, Cohen, S. H., Sosman, A. J., and Fink, J. N. Food-dependent exercise-induced anaphylaxis. J Allergy Clin Immunol 1983;71(4):407-411. PubMed
- Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. A new French multicenter survey]. Ann.Gastroenterol Hepatol (Paris) 1995;31(4):256-263.
- Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery]. Allerg.Immunol.(Paris) 1995;27(6):209.
- Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery cross-reacting with ragweed]. Allerg.Immunol.(Paris) 1995;27(3):91-93.
- Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. A new French multicenter study]. Bull.Acad.Natl.Med 1995;179(1):161-184.
- Puig, L. and de Moragas, J. M. Enhancement of PUVA phototoxic effects following celery ingestion: cool broth also can burn. Arch.Dermatol. 1994;130(6):809-810. DOI
- Egan, C. L. and Sterling, G. Phytophotodermatitis: a visit to Margaritaville. Cutis 1993;51(1):41-42.
- Boffa, M. J., Gilmour, E., and Ead, R. D. Celery soup causing severe phototoxicity during PUVA therapy. Br.J.Dermatol. 1996;135(2):334.
- Wuthrich, B., Borga, A., and Yman, L. Oral allergy syndrome to a jackfruit (Artocarpus integrifolia). Allergy 1997;52(4):428-431.
- Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem.Toxicol. 2006;44(9):147 PubMed
- Baek CH, Bae YJ, Cho YS, Moon HB, Kim TB. Food-dependent exercise-induced anaphylaxis in the celery-mugwort-birch-spice syndrome. Allergy. 2010;65(6):792-3. PubMed
- Khalid Z, Osuagwu FC, Shah B, Roy N, Dillon JE, Bradley R. Celery root extract as an inducer of mania induction in a patient on venlafaxine and St John's Wort. Postgrad Med. 2016;128(7):682-3. PubMed
- Palgan K, Götz-Zbikowska M, Tykwinska M, Napiórkowska K, Bartuzi Z. Celery-cause of severe anaphylactic shock. Postepy Hig Med Dosw (Online). 2012;66:132-4.
- Maljaei MB, Moosavian SP, Mirmosayyeb O, Rouhani MH, Namjoo I, Bahreini A. Effect of celery extract on thyroid function; is herbal therapy safe in obesity? Int J Prev Med 2019;10:55. doi: 10.4103/ijpvm.IJPVM_209_17. PubMed
- Rouhi-Boroujeni H, Hosseini M, Gharipour M, Rouhi-Boroujeni H. Is herbal therapy safe in obesity? A case of Apium graveolens (Celery) induced hyperthyroidism. ARYA Atheroscler 2016;12(5):248-9.
- Emad AM, Ali SF, Abdel-Rahman EA, et al. Anti-inflammatory and antioxidant effects of Apium graveolens L. extracts mitigate against fatal acetaminophen-induced acute liver toxicity. J Food Biochem 2020:e13399. Online ahead of print.
- Shayani Rad M, Moohebati M, Mohajeri SA. Effect of celery (Apium graveolens) seed extract on hypertension: A randomized, triple-blind, placebo-controlled, cross-over, clinical trial. Phytother Res 2022.
- Azimi M, Zahedi MJ, Raeiszadeh M, Iraji A, Cramer H, Pasalar M. Efficacy and Safety of a Persian Medicine Formula on Functional Dyspepsia Symptoms: A Randomized Double-Blind Active-Control Clinical Trial. Complement Med Res 2023;30(3):238-247. PubMed
- Ukleja-Sokolowska N, Lis K, Graczyk M, Bartuzi M, Bartuzi Z. The use of inhibition assay in Api g 7 suspected allergy in a female patient with anaphylaxis: A case report. Int J Immunopathol Pharmacol 2024;38:3946320231223004. PubMed
Sour Cherry 4 references
- Schumacher HR, Pullman-Mooar S, Gupta SR, et al. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage 2013;21(8):1035-41. PubMed
- Seymour EM, Warber SM, Kirakosyan A, et al. Anthocyanin pharmacokinetics and dose-dependent plasma antioxidant pharmacodynamics following whole tart cherry intake in healthy humans. J Funct Food 2014;11:509-16. DOI
- Elliot DL, Kuehl KS, Jones KD, Dulacki K. Using an eccentric exercise-testing protocol to assess the beneficial effects of tart cherry juice in fibromyalgia patients. Integ Med 2010;9(6):25-9.
- Soltanifar A, Moharreri F, Bakhtiari E, Hosseinpour A. The Effect of Adding Sour Cherry Concentrate to The Usual Treatment of Attention Deficit Hyperactivity Disorder In 6 To 12 Years Old Children. J Atten Disord 2023;27(2):214-219. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC