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Dietary supplement

Taurine 500 mg Ingredients & Drug Interactions

by GNC

Taurine 500 mg label
See full label image
Other (e.g. Tea Bag) Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Taurine 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Taurine 500 mg is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for exercise performance and endurance, heart health, energy support.Based on those ingredients, 173 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Taurine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Taurine 500 mg by GNC

Ask about any prescription or over-the-counter medication and we check it for interactions with Taurine 500 mg by GNC — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Taurine 500 mg by GNC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: taurine at 500 mg per serving. Taurine is an amino acid that your body naturally produces and that's found in meat, fish, and dairy.

It's also an inactive ingredient list that includes microcrystalline cellulose, dicalcium phosphate, and several other fillers and binders used to make the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Taurine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supports muscle function.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Physical performance, Muscular dystrophy, Postoperative recovery, Muscle recovery — and 2 related terms.
  • The closest evidence on file: Taurine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Taurine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness, Muscular dystrophy, Physical performance, Postoperative recovery.

Taurine is rated possibly effective for hepatitis and possibly effective for congestive heart failure (CHF) — a condition where the heart can't pump blood efficiently. It's rated possibly ineffective for weight loss (obesity).

The evidence for these uses exists but isn't conclusive, so talk with your doctor about whether this supplement makes sense for your situation.

The evidence, ingredient by ingredient Taurine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taurine is generally well tolerated when used at typical doses for up to one year. The most common side effects are constipation, diarrhea, and indigestion.

Rare serious effects include allergic reactions — particularly in people with a history of allergies to sulfonamides or sulfites — and very isolated reports of cardiovascular concerns, though those cases involved energy drinks with many other ingredients mixed in, so it's unclear if taurine alone was responsible. Taurine is rated likely safe in pregnancy and lactation, and it occurs naturally in breast milk.

However, the safety of supplement doses during lactation is not well studied, so use caution and talk with your doctor or pharmacist before taking it if you're breastfeeding.

Side effects, ingredient by ingredient Taurine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Taurine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 173 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood pressure medications (antihypertensives) and lithium before taking this product — both are moderate-severity interactions. Use the medication checker on this page to run through your exact prescriptions with your doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Taurine may help with hepatitis or heart failure, though evidence is modest. If you take blood pressure medication or lithium, you'll need to check with your doctor or pharmacist first — this supplement could interfere with how those drugs work.

It's generally well tolerated short-term, but long-term safety data is limited, so discuss it with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Taurine 500 mg, straight from the product label.

Brand GNC
Barcode (UPC) 048107211257
Net contents 50 Vegetarian Caplet(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 227831
Product type Non-nutrient/non-botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Taurine 500 mg by GNC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
2 Caplet(s)
UPC/BARCODE
048107211257
IngredientAmount% DV
Taurine500 mg--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Hydroxypropylcellulose, Silicon Dioxide, Hydrogenated Vegetable Oil, Croscarmellose Sodium, Stearic Acid, Ethylcellulose, Magnesium Stearate, Carnauba wax, Triacetin, Diacetylated Monoglycerides, Oleic Acid, Polyethylene Glycol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Storage

Store in a cool, dry place.

Formulation

Supports muscle function

Potency verified by GNC procedure #5097. Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

General Statements

50 servings

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one or two caplets daily with a meal.

Seals/Symbols

Ko Kosher Service

Formula

Ko Kosher Service

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Taurine 500 mg by GNC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Taurine 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Taurine 500 mg by GNC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Taurine

Interacts with
173 drugs
500 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Taurine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Hydroxypropylcellulose, Silicon Dioxide, Hydrogenated Vegetable Oil, Croscarmellose Sodium, Stearic Acid, Ethylcellulose, Magnesium Stearate, Carnauba wax, Triacetin, Diacetylated Monoglycerides, Oleic Acid, Polyethylene Glycol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Taurine 500 mg by GNC Drug Interactions

Want to check YOUR meds against Taurine 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
173Drugs
173 Moderate

Ingredients driving the most interactions

Taurine 173

Individual Drug Interactions

The ingredients in Taurine 500 mg interact with 173 drugs. Click any drug to see the details.

1 of the 1 ingredient in Taurine 500 mg interact with drugs. Each result below shows which ingredient is responsible. Taurine

Each ingredient & the kinds of drugs it affects

For each ingredient in Taurine 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Taurine 500 mg, from the product label.

GNC

See all GNC products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Taurine 500 mg by GNC: Common Questions

Does Taurine 500 mg by GNC interact with any medications?
Yes. Based on its ingredients, Taurine 500 mg has a known interaction with 173 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Taurine 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is taurine, and why is it in this supplement?
Taurine is an amino acid your body makes naturally and gets from food — meat, fish, and dairy are good sources. This supplement provides it as a concentrated dose, often used by people interested in heart health or liver support, though evidence for those uses is still being established.
What side effects might I have?
Most people tolerate it well. The most common complaints are constipation, diarrhea, or indigestion. Allergic reactions are rare but possible, especially if you have a history of allergies to sulfonamides or sulfites — watch for signs of a reaction and stop if anything feels off.
Is it safe to take if I'm pregnant or breastfeeding?
Taurine is rated likely safe in pregnancy and lactation. It naturally occurs in breast milk, but safety data on supplement doses during breastfeeding is limited. Talk with your doctor or pharmacist about whether this supplement makes sense for you if you're nursing.
Does taurine actually help with weight loss?
It's rated possibly ineffective for obesity, so the evidence doesn't support it as a weight-loss aid. If weight management is your goal, talk with your doctor about strategies that are better supported by research.
How long can I safely take this supplement?
Taurine is generally well tolerated for up to one year at typical doses, but long-term safety beyond that is less certain. Check with your doctor or pharmacist about how long it makes sense for you to use it.
Why do I need to check with my doctor about blood pressure or lithium medications?
Taurine can lower blood pressure and might affect how your body clears lithium from your system. Either effect could make those medications work differently than expected, so your doctor or pharmacist needs to know you're taking this before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Taurine 500 mg label
Go deeper

The Full Monographs Behind Taurine 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph →
Sources

Sources & How We Checked

Taurine 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
  9. Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
  10. Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
  14. Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
  17. Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
  19. Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
  20. Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
  21. Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed

See these in context on the Taurine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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