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Dietary supplement

TeaCrine Capsules 100 mg Ingredients & Drug Interactions

by Nootropics Depot

TeaCrine Capsules 100 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking TeaCrine Capsules 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

TeaCrine Capsules 100 mg is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for energy and reduced fatigue, focus and mental alertness, mood support.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Theacrine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against TeaCrine Capsules 100 mg by Nootropics Depot

Ask about any prescription or over-the-counter medication and we check it for interactions with TeaCrine Capsules 100 mg by Nootropics Depot — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of TeaCrine Capsules 100 mg by Nootropics Depot

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

TeaCrine Capsules contain one active ingredient: theacrine, a compound structurally similar to caffeine that's found naturally in certain tea plants and coffee beans. Each capsule delivers 100 mg of theacrine.

The capsule itself is made from vegetable cellulose, and the powder inside also contains microcrystalline cellulose and calcium silicate as inactive ingredients — these are standard fillers and binders that help hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Theacrine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: energy and mental alertness support.
  • We looked for evidence on: Athletic performance, Cognitive function, Fatigue, Mental alertness, endurance, focus.
  • The closest evidence on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Fatigue, Mental alertness.

The evidence for what theacrine actually does isn't established yet in the data we hold. The product is marketed for athletic performance, cognitive function, fatigue, mental alertness, and muscle strength, but we have insufficient reliable evidence to rate any of these claims.

That doesn't mean theacrine doesn't work — it means the research isn't solid enough for us to say one way or the other.

The evidence, ingredient by ingredient Theacrine

How safe is it?

Limited data
Safety Information · database check
Limited information

Little studied safety information is available for these ingredients — that is not the same as being safe.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of theacrine appears generally well tolerated in studies, but long-term safety hasn't been established, so we don't know what happens if you take it for months or years. There isn't enough safety data to recommend theacrine during pregnancy, so you should avoid it if you're pregnant.

The same goes for breastfeeding — the data just isn't there to know whether it's safe for your baby.

Side effects, ingredient by ingredient Theacrine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Theacrine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take TeaCrine, check your medications against our interaction tool if you use CNS depressants — sedatives, sleep aids, anxiety medications, or certain pain relievers. Theacrine might alter how these work, and the effect could go either way depending on the dose.

Even though we haven't seen this reported in real patients, the interaction is rated Moderate and worth confirming.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is limited.

TeaCrine is a single-ingredient product containing theacrine, a caffeine-like compound without solid evidence yet for the claims made about it. If you take CNS depressants — sedatives, sleep aids, or certain pain medications — you need to check with us first.

Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or on any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about TeaCrine Capsules 100 mg, straight from the product label.

Brand Nootropics Depot
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 232644
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for TeaCrine Capsules 100 mg by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Theacrine100 mg--

Other ingredients: Microcrystalline Cellulose, Calcium Silicate, Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Precautions

Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.

Warning: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any diseases. These statements have not been evaluated by the Food & Drug Administration.

Brand IP Statement(s)

TeaCrine is a registered trademark and protected by Patents Pending, Serial No. 61/903,362;under exclusive global distribution by Compound Solutions, Inc.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily.

Storage

Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

TeaCrine Capsules 100 mg by Nootropics Depot label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

TeaCrine Capsules 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in TeaCrine Capsules 100 mg by Nootropics Depot

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Theacrine

Interacts with
248 drugs
100 mg per serving

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studie...

Theacrine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Calcium Silicate, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

TeaCrine Capsules 100 mg by Nootropics Depot Drug Interactions

Want to check YOUR meds against TeaCrine Capsules 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

Theacrine 248

Individual Drug Interactions

The ingredients in TeaCrine Capsules 100 mg interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in TeaCrine Capsules 100 mg interact with drugs. Each result below shows which ingredient is responsible. Theacrine

Each ingredient & the kinds of drugs it affects

For each ingredient in TeaCrine Capsules 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Theacrine1 drug type · 248 drugs

Cns Depressants

Theoretically, theacrine might alter the effects of CNS depressants.
Animal research shows that low doses of theacrine have sedating effects, whereas high doses might have stimulant effects. Depending on the dose of theacrine used, it might increase or decrease the effects of CNS depressants. However, these effects have not yet been reported in humans.

Likelihood Possible Evidence D
Theacrine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for TeaCrine Capsules 100 mg, from the product label.

Nootropics Depot

See all Nootropics Depot products
Name
Nootropics Depot
Street Address
8380 S. Kyrene Rd. Ste. 110
City
Tempe
State
AZ
ZipCode
85284
Web Address
nootropicsdepot.com
Pharmacist Counseling Corner

TeaCrine Capsules 100 mg by Nootropics Depot: Common Questions

Does TeaCrine Capsules 100 mg by Nootropics Depot interact with any medications?
Yes. Based on its ingredients, TeaCrine Capsules 100 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
TeaCrine Capsules 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is theacrine like caffeine?
Theacrine is structurally similar to caffeine and is found naturally in tea plants and coffee beans, but they're not the same compound. We don't have established evidence yet for what theacrine actually does for energy, focus, or athletic performance.
Is it safe to take long-term?
Short-term use appears generally well tolerated in studies, but long-term safety hasn't been established. If you're thinking about taking it for months, that's worth discussing with your pharmacist.
Can I take this while pregnant or breastfeeding?
No — there isn't enough safety data, so avoid it during pregnancy and while breastfeeding. Talk to your OB or midwife if you're looking for alternatives.
What's in the capsule besides theacrine?
The capsule is made of vegetable cellulose, and inside there's microcrystalline cellulose and calcium silicate as inactive fillers to hold it together. There's nothing else.
Does theacrine interact with sleep medications?
Yes — theacrine is documented to interact with CNS depressants, which include sleep aids and sedatives. The interaction is Moderate, meaning theacrine could theoretically increase or decrease their effects. Check your exact medications with our tool before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if TeaCrine Capsules 100 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

TeaCrine Capsules 100 mg label
Go deeper

The Full Monographs Behind TeaCrine Capsules 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theacrine

Interacts with 248 drugs

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studies suggest it may give a stimulant-like b...

Read the full Theacrine monograph →
Sources

Sources & How We Checked

TeaCrine Capsules 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theacrine 1 reference
  1. Xu JK, Kurihara H, Zhao L, Yao XS. Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice. J Asian Nat Prod Res 2007;9(6-8):665-72.

See these in context on the Theacrine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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