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Dietary supplement

Theacrine 100 mg Ingredients & Drug Interactions

by Double Wood Supplements

Theacrine 100 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Theacrine 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Theacrine 100 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for energy and reduced fatigue, focus and mental alertness, mood support.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Theacrine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Theacrine 100 mg by Double Wood Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Theacrine 100 mg by Double Wood Supplements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Theacrine 100 mg by Double Wood Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: theacrine. It's a naturally occurring alkaloid structurally similar to caffeine that's being studied for potential effects on energy, focus, and athletic performance.

The capsule also contains gelatin and microcrystalline cellulose, which are standard inactive ingredients that help form and fill the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Theacrine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: energy, mental focus and performance.
  • We looked for evidence on: Cognitive function, Fatigue, Mental alertness.
  • The closest evidence on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function (Natural Medicines).
  • Also on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Fatigue, Mental alertness.

The evidence we hold doesn't yet support using theacrine for athletic performance, cognitive function, fatigue, mental alertness, or muscle strength — the data is too limited to rate it either way. If you're considering this product for any of those reasons, understand that we don't have reliable evidence that it works for them yet.

The evidence, ingredient by ingredient Theacrine

How safe is it?

Limited data
Safety Information · database check
Limited information

Little studied safety information is available for these ingredients — that is not the same as being safe.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use appears generally well tolerated in studies, but long-term safety hasn't been established, so we don't know what happens if you take it regularly for months or years. There isn't enough safety data to use theacrine during pregnancy or while breastfeeding — the product facts advise against both.

If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this.

Side effects, ingredient by ingredient Theacrine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Theacrine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you use any CNS depressants — sedating medications like benzodiazepines, sleep aids, opioids, or other drugs that slow your central nervous system. Theacrine may either increase or decrease their effects, and that interaction is rated Moderate.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is limited.

Theacrine is a single-ingredient supplement that's been studied for energy and focus, but the evidence isn't strong enough yet to say it works for those purposes. Its main concern is a possible unpredictable interaction with CNS depressants (sedating medications), so if you take any of those, check with your own doctor or pharmacist before starting.

Short-term use looks okay in studies, but long-term safety is unknown.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Theacrine 100 mg, straight from the product label.

Brand Double Wood Supplements
Barcode (UPC) 07437243543798
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 241951
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Theacrine 100 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
07437243543798
IngredientAmount% DV
Theacrine100 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one or two capsules (100-200mg) to boost energy and mental performance. Do not consume more than 4 capsules in one day and space out doses 3-4 hours. If combining with caffeine take one capsule (100mg) and do not consume more than 200mg of coffee.

Formula

Product Information: Theacrine is a small alkaloid molecule which can be seen as a structurally modified version of caffeine. Studies have shown that Theacrine effects the body in a similar fashion as Caffeine with some key difference. Theacrine has a softer crash, is less likely to cause anxiety, and tolerance to Theacrine develops more slowly.

Storage

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature.

Brand IP Statement(s)

Visit www.theacrinedepot.com for more product information. TeaCrine is a registered trademark and protected by Patents Pending, Serial No. 61/903,362 under exclusive global distribution by Compound Solutions, Inc.

Formulation

Supports mental focus and motivation Promotes energy and stamina levels

FDA Statement of Identity

Dietary Supplement

General Statements

TeaCrine

Precautions

Warning: Consult your physician before using this product. Do not consume more than 4 capsules per day, allowing at least 3 hours between doses.

Do not take this product if you are pregnant, nursing, or taking any other medications.

Do not combine this product with more than 200mg of caffeine when taken on the same day. Taking this product with caffeine can increase chance of nervousness, irritability and sleeplessness.

Discontinue use and consult your doctor immediately if any adverse reactions occur.

Do not take Theacrine and operate any heavy machinery until you know how it affects you.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Theacrine 100 mg by Double Wood Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Theacrine 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Theacrine 100 mg by Double Wood Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Theacrine

Interacts with
248 drugs
100 mg per serving

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studie...

Theacrine monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Theacrine 100 mg by Double Wood Supplements Drug Interactions

Want to check YOUR meds against Theacrine 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

Theacrine 248

Individual Drug Interactions

The ingredients in Theacrine 100 mg interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Theacrine 100 mg interact with drugs. Each result below shows which ingredient is responsible. Theacrine

Each ingredient & the kinds of drugs it affects

For each ingredient in Theacrine 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Theacrine1 drug type · 248 drugs

Cns Depressants

Theoretically, theacrine might alter the effects of CNS depressants.
Animal research shows that low doses of theacrine have sedating effects, whereas high doses might have stimulant effects. Depending on the dose of theacrine used, it might increase or decrease the effects of CNS depressants. However, these effects have not yet been reported in humans.

Likelihood Possible Evidence D
Theacrine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Theacrine 100 mg, from the product label.

Double Wood Supplements

See all Double Wood Supplements products
Name
Double Wood LLC
Street Address
PO Box 344 200 Mill St.
City
Danville
State
PA
ZipCode
17821
Web Address
www.dhmdepot.com
Pharmacist Counseling Corner

Theacrine 100 mg by Double Wood Supplements: Common Questions

Does Theacrine 100 mg by Double Wood Supplements interact with any medications?
Yes. Based on its ingredients, Theacrine 100 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Theacrine 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is theacrine like caffeine?
Theacrine is structurally similar to caffeine and is a naturally occurring alkaloid, but they're not the same compound. We don't yet have strong evidence on how theacrine actually performs in your body for energy or focus, so you can't assume it works just like caffeine would.
Can I take this if I'm pregnant or breastfeeding?
No, there isn't enough safety data. The product facts advise against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether this is right for your situation.
How long can I take this safely?
Short-term use appears generally well tolerated in studies, but long-term safety hasn't been established. We don't know what happens with regular use over months or years, so discuss your timeline with your doctor or pharmacist.
Will this help with fatigue, focus, or athletic performance?
The evidence we have isn't reliable enough to say. Theacrine is being studied for those purposes, but we can't yet confirm it works for any of them.
Are there any reported side effects?
No adverse effects are documented in the data we hold, but short-term use is what's been studied — long-term side effects aren't well known.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Theacrine 100 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Theacrine 100 mg label
Go deeper

The Full Monographs Behind Theacrine 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theacrine

Interacts with 248 drugs

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studies suggest it may give a stimulant-like b...

Read the full Theacrine monograph →
Sources

Sources & How We Checked

Theacrine 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theacrine 1 reference
  1. Xu JK, Kurihara H, Zhao L, Yao XS. Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice. J Asian Nat Prod Res 2007;9(6-8):665-72.

See these in context on the Theacrine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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