Major interaction on record — check this product against your medications before combining. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Thyro8 Ingredients & Drug Interactions

by A Deal Media Company

Thyro8 label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Thyro8 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Thyro8 is a dietary supplement by A Deal Media Company with 6 active ingredients. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 797 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Theobromine, Selenium, Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Thyro8 by A Deal Media Company

Ask about any prescription or over-the-counter medication and we check it for interactions with Thyro8 by A Deal Media Company — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Thyro8 by A Deal Media Company

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.
  • “T8 Power Blend” is a proprietary blend — the label gives one combined amount (425 mg) without saying how much of each component you get.

Thyro8 contains 6 active ingredients. Selenium supports thyroid function and may help prevent selenium deficiency-related conditions.

Vitamin K2 is a form of vitamin K that plays a role in bone health and blood clotting. Iodine is essential for thyroid hormone production and your body's overall metabolism.

The product also contains theobromine (a compound related to caffeine), hydroxytyrosol acetate (derived from olive), and guggulsterone extract (from the guggul plant). The tablet also includes inactive ingredients like microcrystalline cellulose, maltodextrin, magnesium stearate, and dicalcium phosphate, which are common binders and fillers.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Thyroid support, energy, mood and focus.
  • We looked for evidence on: Hypothyroidism, Autoimmune thyroiditis, Iodine deficiency, Chronic fatigue syndrome (CFS), Depression, Cognitive impairment — and 4 related terms.
  • The strongest evidence on file: Iodine is rated "Likely Effective" for Iodine deficiency (Natural Medicines).
  • Also on file: Selenium is rated "Possibly Effective" for Autoimmune thyroiditis.
  • Also on file: Cocoa is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline, Chronic fatigue syndrome (CFS), Cognitive impairment, Fatigue.

Selenium in this product is likely effective for preventing selenium deficiency and possibly effective for autoimmune thyroiditis (an immune-related thyroid condition), Kashin-Beck disease (a joint and bone disorder), and pre-eclampsia in pregnancy. It appears ineffective for dyslipidemia (abnormal blood lipids).

Vitamin K2 is effective for correcting vitamin K deficiency and related clotting disorders and possibly effective for osteoporosis. Iodine is likely effective for preventing iodine deficiency and possibly effective for oral mucositis and periodontitis (gum disease).

For the other three ingredients — theobromine, hydroxytyrosol acetate, and guggulsterone extract — we don't have effectiveness data on file.

The evidence, ingredient by ingredient Selenium Vitamin K Iodine Cocoa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Selenium is generally well tolerated in normal amounts, but high-dose supplements carry real risks. Excess selenium can cause gastric discomfort, headache, and rash; at very high levels it can trigger serious effects like alopecia (hair loss), nail changes, nausea, vomiting, and in rare cases, multi-organ failure.

Chronic high exposure may raise your risk of neurotoxicity and motor nerve damage. Vitamin K2 is generally well tolerated orally; the most common side effects are mild — diarrhea, nausea, and stomach upset.

Iodine is well tolerated in normal dietary amounts, but high doses can cause thyroid problems, including goiter and abnormal thyroid function, as well as rashes, a metallic taste, and rarely, serious allergic reactions. Pregnancy and lactation safety data are available for vitamin K (likely safe) and iodine (likely safe in pregnancy, possibly unsafe for lactation at high doses), but no safety data are on file for selenium, theobromine, hydroxytyrosol acetate, or guggulsterone extract during pregnancy or breastfeeding — talk to your doctor before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Selenium Vitamin K Iodine Cocoa

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Iodine, Cocoa, Vitamin K, Selenium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; lithium.
  • For scale: 797 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Thyro8, double-check if you're on warfarin or other blood thinners and antiplatelet drugs (Major and Moderate risk of increased bleeding). Also verify with your pharmacist if you take lithium, antithyroid drugs, amiodarone, immunosuppressants, barbiturates, or niacin — all have Moderate interactions documented with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you're on warfarin, lithium, antithyroid drugs, amiodarone, immunosuppressants, barbiturates, or blood thinners, you need to check this product with your pharmacist or doctor first. Even if you're not on those medications, this product has a broad interaction potential, so verify your exact drugs before starting.

It's a good idea to discuss this supplement with your pharmacist, especially regarding dose and any thyroid or bleeding concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Thyro8, straight from the product label.

Brand A Deal Media Company
Barcode (UPC) 752830893467
Net contents 60 Vegan Tablet(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 249585
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Thyro8 by A Deal Media Company, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 All-Natural Vegan Tablet(s)
Maximum serving Sizes:
2 All-Natural Vegan Tablet(s)
Servings per container
30
UPC/BARCODE
752830893467
IngredientAmount% DV
Theobromine0 NP--
Selenium200 mcg286%
Vitamin K2180 mcg225%
Iodine150 mcg100%
T8 Power Blend425 mg--
Hydroxytyrosol Acetate0 NP--
Guggulsterone extract0 NP--

Other ingredients: Microcrystalline Cellulose, Maltodextrin, Magnesium Stearate, Dicalcium Phosphate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Two tablets in the morning with breakfast.

Formulation

Elevate mood Enhance focus Improve energy Boost metabolism Support circulation Promote healthy skin & hair

Gluten Free NON GMO

100% Vegan

Thyroid support

Seals/Symbols

GMP Certified

General Statements

100% money back guaranteed

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Warning: Keep out of reach of children. This product is not intended for children under the age of 18, or pregnant or nursing mothers, or individuals taking prescription drugs.

This product is not intended for children under the age of 18, or pregnant or nursing mothers, or individuals taking prescription drugs. If you are taking prescription drugs, have a known medical condition, or have any questions about the advisability of this product, consult your doctor before use.

Do not exceed the recommended dose.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Thyro8 by A Deal Media Company label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Thyro8 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Thyro8 by A Deal Media Company

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 All-Natural Vegan Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Selenium

Interacts with
321 drugs
200 mcg per serving Form: L-Selenomethionine

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...

Selenium monograph & interactions

Vitamin K2

Interacts with
2 drugs
180 mcg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Iodine

Interacts with
7 drugs
150 mcg per serving Form: Potassium Iodide

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...

Iodine monograph & interactions

T8 Power Blend

425 mg per serving
  • › Theobromine
  • › Hydroxytyrosol Acetate
  • › Guggulsterone extract

Other (inactive) ingredients: Microcrystalline Cellulose, Maltodextrin, Magnesium Stearate, Dicalcium Phosphate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Thyro8 by A Deal Media Company Drug Interactions

Want to check YOUR meds against Thyro8?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
797Drugs
2 Major 766 Moderate 29 Minor

Ingredients driving the most interactions

Theobromine 661
Selenium 321
Iodine 7
Vitamin K2 2

Individual Drug Interactions

The ingredients in Thyro8 interact with 797 drugs. Click any drug to see the details.

4 of the 6 ingredients in Thyro8 interact with drugs. Each result below shows which ingredient is responsible. Theobromine Selenium Iodine Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Thyro8 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Theobromine37 drug types · 661 drugs

Ace Inhibitors (Aceis)

Theoretically, taking cocoa with ACEIs might increase the risk of adverse effects.
Human research shows that dark chocolate can inhibit ACE. Additionally, prolonged angioedema in an elderly patient on an ACE inhibitor was precipitated with intake of diabetic chocolate.

Likelihood Possible Evidence D
Adenosine (Adenocard)

Theoretically, cocoa might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Cocoa contains caffeine. Caffeine is a competitive inhibitor of adenosine at the cellular level. However, caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole than adenosine-induced stress testing.

Likelihood Possible Evidence B
Alcohol (Ethanol)

Theoretically, concomitant use might increase levels and adverse effects of caffeine.
Cocoa contains caffeine. Alcohol reduces caffeine metabolism. Concomitant use of alcohol can increase caffeine serum concentrations and the risk of caffeine adverse effects.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, cocoa may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research shows that intake of cocoa can inhibit platelet adhesion, aggregation, and activity and increase aspirin-induced bleeding time. For patients on dual antiplatelet therapy, cocoa may enhance the inhibitory effect of clopidogrel, but not aspirin, on platelet aggregation.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking cocoa with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that cocoa can modestly decrease blood pressure in hypertensive and normotensive patients.

Likelihood Possible Evidence D
Beta-Adrenergic Agonists

Theoretically, large amounts of cocoa might increase the cardiac inotropic effects of beta-agonists.
Cocoa contains caffeine. Theoretically, large amounts of caffeine might increase cardiac inotropic effects of beta-agonists. A case of atrial fibrillation associated with consumption of large quantities of chocolate in a patient with chronic albuterol inhalation abuse has also been reported.

Likelihood Probable Evidence D
Cytochrome P450 1A2 (Cyp1A2) Inhibitors

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Cocoa contains caffeine. Caffeine is metabolized by cytochrome P450 1A2 (CYP1A2),. Theoretically, drugs that inhibit CYP1A2 may decrease the clearance rate of caffeine from cocoa and increase caffeine levels.

Likelihood Possible Evidence D
Dipyridamole (Persantine)

Theoretically, cocoa might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Cocoa contains caffeine. Caffeine may inhibit dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram might increase the risk of adverse effects from caffeine.
Cocoa contains caffeine. In human research, disulfiram decreases the rate of caffeine clearance.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, using cocoa with diuretic drugs might increase the risk of hypokalemia.
Cocoa contains caffeine. In excessive amounts, caffeine can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Ephedrine

Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Cocoa contains caffeine. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Cocoa contains caffeine. Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Flutamide (Eulexin)

Theoretically, cocoa might increase the levels and adverse effects of flutamide.
Cocoa contains caffeine. In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide.

Likelihood Possible Evidence D
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Cocoa contains caffeine. Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence D
Lithium

Theoretically, abrupt cocoa withdrawal might increase the levels and adverse effects of lithium.
Cocoa contains caffeine. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Cocoa contains caffeine. Large amounts of caffeine with MAOIs might precipitate a hypertensive crisis.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Cocoa contains caffeine. Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, cocoa might decrease the effects of pentobarbital.
Cocoa contains caffeine. Caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

Theoretically, cocoa might reduce the effects of phenobarbital and increase the risk for convulsions.
Cocoa contains caffeine. Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. The exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Cocoa contains caffeine. Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, cocoa might reduce the effects of phenytoin and increase the risk for convulsions.
Cocoa contains caffeine. Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Cocoa contains caffeine. Quinolones (also referred to as fluoroquinolones) decrease caffeine clearance.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Cocoa contains caffeine. Caffeine and riluzole are both metabolized by cytochrome P450 1A2, and concomitant use might reduce metabolism of one or both agents.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, concomitant use might increase stimulant adverse effects.
Cocoa contains caffeine. Concomitant use might increase the risk of stimulant adverse effects.

Likelihood Probable Evidence C
Theophylline

Theoretically, cocoa might increase the levels and adverse effects of theophylline.
Cocoa contains caffeine. Large amounts of caffeine might inhibit theophylline metabolism. Caffeine decreases theophylline clearance 23% to 29%.

Likelihood Probable Evidence B
Theobromine full monograph & all 37 interactions

Selenium6 drug types · 321 drugs

Anticoagulant/Antiplatelet Drugs

Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.

Likelihood Possible Evidence D
Barbiturates

Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.

Likelihood Possible Evidence D
Contraceptive Drugs

Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.

Likelihood Possible Evidence B
Niacin

Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Selenium full monograph & interactions

Iodine3 drug types · 7 drugs

Amiodarone (Cordarone)

Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Probable Evidence D
Lithium

Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.

Likelihood Probable Evidence D
Iodine full monograph & interactions

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Thyro8, from the product label.

A Deal Media Company

See all A Deal Media Company products
Name
A Deal Media Company
Street Address
881 Corporate Dr.
City
Lexington
State
KY
ZipCode
40503
Phone Number
(800) 683-3958
Web Address
www.thyro8.com
Pharmacist Counseling Corner

Thyro8 by A Deal Media Company: Common Questions

Does Thyro8 by A Deal Media Company interact with any medications?
Yes. Based on its ingredients, Thyro8 has a known interaction with 797 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Thyro8 contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Thyro8 safe to take if I'm pregnant or breastfeeding?
Vitamin K2 in this product is likely safe in pregnancy, but iodine carries some uncertainty — the facts show it's likely safe in pregnancy but possibly unsafe during lactation at high doses. We have no pregnancy or breastfeeding safety data for selenium, theobromine, hydroxytyrosol acetate, or guggulsterone extract. You should talk to your doctor or pharmacist before taking this product while pregnant or nursing.
What are the side effects I should watch for?
The most common ones from selenium are gastric discomfort, headache, and rash. Vitamin K2 may cause diarrhea, nausea, or stomach upset. Iodine can cause nausea, diarrhea, headache, or a metallic taste. At high doses, selenium and iodine carry more serious risks — excess selenium can cause hair loss and nail damage, while excess iodine can damage your thyroid. If you experience any of these, stop and talk to your pharmacist or doctor.
Does Thyro8 actually work for thyroid health?
Selenium is likely effective for preventing selenium deficiency and possibly effective for autoimmune thyroiditis. Iodine is likely effective for preventing iodine deficiency, which is essential for thyroid function. Vitamin K2 doesn't directly target thyroid function but is effective for bone health and clotting. Whether this combination works for general thyroid support isn't established in our data — ask your doctor if it's right for your specific situation.
Can I take this if I'm on warfarin?
No — not without talking to your doctor first. Vitamin K2 in this product can reverse warfarin's blood-thinning effects, and selenium may also interfere with warfarin. This is a Major interaction that could put you at serious risk. Do not start this supplement if you're on warfarin without explicit approval from your prescriber.
What's the difference between Vitamin K and Vitamin K2?
Vitamin K2 is one form of vitamin K. Both forms are important for blood clotting and bone health, but vitamin K2 is found mainly in fermented foods and animal products and is the form in this product. The interaction with warfarin applies to both forms.
Is there a risk of taking too much selenium from this product?
Yes. The facts note that selenium can be toxic in excess and advise against high-dose supplements unless your doctor recommends them. The tolerable upper limit is 400 mcg daily; above that, you risk gastric upset, headache, rash, hair loss, nail damage, and at very high doses, serious organ damage. Ask your pharmacist what dose is in each tablet and whether it's safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Thyro8 label
Go deeper

The Full Monographs Behind Thyro8’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Selenium

Interacts with 321 drugs

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who eat a varied diet get enough, and supple...

Read the full Selenium monograph → Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph → Herb & supplement monograph

Iodine

Interacts with 7 drugs

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements help when you are truly deficient, but...

Read the full Iodine monograph → Herb & supplement monograph

Cocoa

Interacts with 661 drugs

Cocoa is rich in plant compounds called flavanols that may modestly support blood vessel function and blood pressure, but most chocolate products are high in sugar, fat, and calories, which...

Read the full Cocoa monograph →
Sources

Sources & How We Checked

Thyro8's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 192 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cocoa 119 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
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See these in context on the Cocoa monograph →

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Iodine 26 references
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