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Dietary supplement

Tongkat Ali Express 100 mg Ingredients & Drug Interactions

by Amazing Herbs

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Tongkat Ali Express 100 mg is a dietary supplement by Amazing Herbs with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Tongkat Ali Express 100 mg by Amazing Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Tongkat Ali Express contains one active ingredient: Tongkat Ali extract, a plant preparation from Eurycoma longifolia roots. The liquid form also includes water and glycerin as inactive ingredients to deliver the extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Male vitality and performance support.
  • We looked for evidence on: Age-related testosterone deficiency, Athletic performance, Erectile dysfunction (ED), Male Infertility, Muscle strength, Sexual desire — and 2 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Muscle strength, Age-related testosterone deficiency, Male Infertility.

The evidence here is mixed. Tongkat Ali is possibly effective for sexual desire based on the data we hold.

For athletic performance, the evidence suggests it's possibly ineffective. Back pain, osteoporosis, and diabetes all have insufficient reliable evidence, so we can't say whether it works for those uses.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tongkat Ali is generally well tolerated in short-term studies, but long-term safety and product quality aren't well established. The main concern is testosterone: research suggests this supplement can raise testosterone levels, and if your testosterone goes beyond normal range, you risk acne, insulin resistance, liver damage, and other hormone-related side effects.

The safety data advises against using it during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Tongkat Ali Express, double-check with your pharmacist if you take propranolol (Inderal) for your heart or blood pressure — this supplement can make it less effective. Also flag any medications that your liver breaks down, including certain antidepressants, blood thinners, and other common drugs.

If you're on testosterone replacement, let your pharmacist know, since this supplement may raise testosterone further.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in Tongkat Ali for sexual desire and you're not on propranolol or other medications affected by liver enzyme interactions, ask your pharmacist to check your medication list first. Avoid it if you're pregnant or breastfeeding.

Anyone with a history of hormonal sensitivity or liver concerns should talk with their doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tongkat Ali Express 100 mg, straight from the product label.

Brand Amazing Herbs
Barcode (UPC) 665231610017
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 273446
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tongkat Ali Express 100 mg by Amazing Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.62 mL
Maximum serving Sizes:
0.62 mL
Servings per container
48
UPC/BARCODE
665231610017
IngredientAmount% DV
Tongkat Ali extract62 mg--

Other ingredients: Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Tongkat Ali Express Liquid Extract is made from 100% Pure Eurycoma Longifolia, a powerful root grown in Indonesia and Malaysia. Also known as Pasak Bumi and 'Ali's Stick'.

100mg 100% Pure Tongkat Ali alcohol free liquid extract

Suggested/Recommended/Usage/Directions

Suggested Use: Take one dropper-full or 1/8 teaspoon (0.62ml) orally, 1-3 times a day, or as needed. Shake well before use.

Formulation

100% Pure Tongkat Ali alcohol free liquid extract

FDA Statement of Identity

Dietary Supplement

See for yourself

Tongkat Ali Express 100 mg by Amazing Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tongkat Ali Express 100 mg by Amazing Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.62 mL Dosage formLiquid Servings per container48 Amounts shown are per serving.

Tongkat Ali extract

Interacts with
248 drugs
62 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Tongkat Ali extract monograph & interactions

Other (inactive) ingredients: Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tongkat Ali Express 100 mg by Amazing Herbs Drug Interactions

Want to check YOUR meds against Tongkat Ali Express 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Tongkat Ali Express 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tongkat Ali extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Tongkat Ali Express 100 mg, from the product label.

Amazing Herbs

See all Amazing Herbs products
Name
Amazing Herbs
City
Buford
State
GA
ZipCode
30518
Phone Number
1-800-241-9138
Web Address
www.amazingherbs.com
Pharmacist Counseling Corner

Tongkat Ali Express 100 mg by Amazing Herbs: Common Questions

Does Tongkat Ali Express 100 mg by Amazing Herbs interact with any medications?
Yes. Based on its ingredients, Tongkat Ali Express 100 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tongkat Ali Express 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against it during pregnancy, and there isn't enough reliable safety information for breastfeeding. Talk with your doctor or pharmacist about other options.
Will Tongkat Ali help with my sexual desire?
It's possibly effective for that according to our data, but results aren't guaranteed. Your individual response may differ, and you'll want to make sure it doesn't interact with your medications first.
What are the side effects?
If this supplement raises your testosterone beyond the normal range, you could develop acne, insulin resistance, liver damage, or other hormone-related effects. Short-term studies show it's generally well tolerated, but long-term safety data are limited.
How long is it safe to take?
The safety data we have covers short-term use in studies. Long-term safety isn't well established, so check with your pharmacist about how long you should take it.
Is this effective for back pain or osteoporosis?
We don't have enough reliable evidence to say whether Tongkat Ali works for either of those. If you're considering it for those uses, talk with your doctor about proven options first.
What's in the liquid besides the active ingredient?
Water and glycerin — those are the inactive ingredients that make up the liquid form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tongkat Ali Express 100 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tongkat Ali Express 100 mg label
Sources

Sources & How We Checked

Tongkat Ali Express 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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