Tongkat Ali Express 100 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Tongkat Ali Express 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tongkat Ali Express 100 mg is a dietary supplement by Amazing Herbs with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Tongkat Ali Express 100 mg by Amazing Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Tongkat Ali Express 100 mg by Amazing Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Tongkat Ali Express 100 mg by Amazing Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Tongkat Ali Express is a liquid supplement containing one active ingredient: Tongkat Ali extract at 100 mg per dose. The extract comes from the roots of Eurycoma longifolia, a plant traditionally used in Southeast Asia.
The liquid is made up of water and glycerin as inactive ingredients.
Does it work?
Moderate evidence
The evidence for Tongkat Ali is mixed. It's rated possibly effective for sexual desire — some research supports this use.
For athletic performance, the evidence suggests it's possibly ineffective. The data we hold doesn't establish enough reliable evidence to rate it for back pain, osteoporosis, or diabetes, so we can't say whether it helps with those.
How safe is it?
Well-documented data
Tongkat Ali is generally well tolerated in short-term studies, but we don't have solid long-term safety data, and the quality of products can vary. One concern is that it may raise testosterone levels beyond the normal range, which could lead to acne, insulin resistance, liver problems, or other testosterone-related side effects.
Do not use this product during pregnancy — there isn't enough safety data, and possible hormonal effects make it inadvisable. Avoid it while breastfeeding as well, since reliable safety information is lacking.
Meds to double-check
Moderate interaction found
Before you start Tongkat Ali Express, check with your pharmacist or doctor if you take propranolol (Inderal) or any other beta-blocker — the most serious risk is reduced effectiveness. Also flag any medications processed by CYP1A2, CYP2C19, or CYP2A6 liver enzymes (Minor risk of increased levels), and let them know if you're on testosterone therapy (Minor risk of further testosterone elevation).
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Tongkat Ali Express may be worth considering if you're interested in sexual desire support and want to check it against your medications first. If you take propranolol or any heart or blood pressure medication, or if you're on testosterone therapy, talk with your doctor or pharmacist before starting — the interaction with propranolol is real and could affect how well your medication works.
Pregnant or breastfeeding? Skip it.
Have your pharmacist or doctor review your exact medication list with this product.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tongkat Ali Express 100 mg, straight from the product label.
| Brand | Amazing Herbs |
|---|---|
| Barcode (UPC) | 665231610017 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 273446 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tongkat Ali Express 100 mg by Amazing Herbs, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Tongkat Ali Express Liquid Extract is made from 100% Pure Eurycoma Longifolia, a powerful root grown in Indonesia and Malaysia. Also known as Pasak Bumi and 'Ali's Stick'.
100mg 100% Pure Tongkat Ali alcohol free liquid extract
Suggested/Recommended/Usage/Directions
Suggested Use: Take one dropper-full or 1/8 teaspoon (0.62ml) orally, 1-3 times a day, or as needed. Shake well before use.
Formulation
100% Pure Tongkat Ali alcohol free liquid extract
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tongkat Ali Express 100 mg by Amazing Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tongkat Ali Express 100 mg by Amazing Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.62 mL Dosage formLiquid Servings per container48 Amounts shown are per serving.
Tongkat Ali extract
Interacts with249 drugs
Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...
Tongkat Ali extract monograph & interactionsOther (inactive) ingredients: Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Tongkat Ali Express 100 mg by Amazing Herbs Drug Interactions
HelloPharmacist Interaction Report
Tongkat Ali Express by Amazing Herbs interacts with medications through its single active ingredient, Tongkat Ali extract.
The most serious interaction is with propranolol (Inderal), a beta-blocker used for heart rhythm and blood pressure control — Tongkat Ali can reduce propranolol levels by about 29%, which may weaken its effect on your heart and blood pressure.
Read the full breakdown — every affected drug type, severity by severity
Tongkat Ali also theoretically may increase levels of several other drug types by weakly inhibiting enzymes your liver uses to break them down. These include CYP1A2 substrates (Minor), CYP2C19 substrates (Minor), and CYP2A6 substrates (Minor) — though this effect has only been seen in lab studies, not yet in people.
Additionally, if you take testosterone therapy or supplements, Tongkat Ali may raise testosterone levels further (Minor).
Altogether, these interactions span 248 individual medications. Use the interaction checker below with your exact medications before you start, and talk with your doctor or pharmacist about any of these drug types — especially propranolol.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tongkat Ali Express 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tongkat Ali Express 100 mg interact with 249 drugs. Click any drug to see the details.
1 of the 1 ingredient in Tongkat Ali Express 100 mg interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali extract
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Extract + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Extract + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Tongkat Ali Extract + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Tongkat Ali Extract + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Tongkat Ali Express 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Tongkat Ali ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Tongkat Ali Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tongkat Ali Express 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Tongkat Ali extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for Tongkat Ali Express 100 mg, from the product label.
Amazing Herbs
See all Amazing Herbs products- Name
- Amazing Herbs
- City
- Buford
- State
- GA
- ZipCode
- 30518
- Phone Number
- 1-800-241-9138
- Web Address
- www.amazingherbs.com
Tongkat Ali Express 100 mg by Amazing Herbs: Common Questions
Does Tongkat Ali Express 100 mg by Amazing Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does Tongkat Ali actually help with sexual desire?
Can I take this while pregnant?
What's the risk of raising testosterone too high?
Is this supplement safe to take long-term?
What happens if I take this with propranolol for my heart?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Tongkat Ali Express 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tongkat Ali Express 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Tongkat Ali Express 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC