Total Enzymes Ingredients & Drug Interactions
by Nutri-West
What is this page for?
First and foremost: checking Total Enzymes against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Total Enzymes is a dietary supplement by Nutri-West with 8 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are in a base of pure Beet Root fiber. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Total Enzymes by Nutri-West
Ask about any prescription or over-the-counter medication and we check it for interactions with Total Enzymes by Nutri-West — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Total Enzymes by Nutri-West
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients list an amount, but at least one is hidden in a blend or missing.
Why this rating?
- The label discloses an exact amount for 7 of its 8 active ingredients.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 4 matched ingredients can interact with medications — Beet.
- The most serious interaction on file is rated Moderate.
- For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 4 of 4.
- General safety write-ups exist for 4 of 4.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryPartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 4 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Total Enzymes, straight from the product label.
| Brand | Nutri-West |
|---|---|
| Net contents | 120 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Dec 24, 2013 |
| DSLD ID | 28434 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Total Enzymes by Nutri-West, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 4500 DU | -- |
| Protease | 15000 HUT | -- |
| Lipase | 65 LU | -- |
| Lactase | 200 LACU | -- |
| Cellulase | 60 CU | -- |
| Invertase | 0.25 IAU | -- |
| Diastase | 150 DP(0) | -- |
| in a base of pure Beet Root fiber | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
General Statements
Manufactured under strict GMP and USP guidelines.
"When You Want The Best"
1115 MFG07/2010
FOR DISTRIBUTION BY HEALTH CARE PROFESSIONALS ONLY.
Precautions
KEEP OUT OF REACH OF CHILDREN.
TAMPER RESISTANT OUTER SEAL - DO NOT USE IF BROKEN.
Formula
High Potency Plant Enzymes
FDA Statement of Identity
Dietary Supplement
Formulation
Contains no starch, salt, sugar, wheat, corn,yeast, soy, milk, gluten, or preservatives.
Suggested/Recommended/Usage/Directions
Directions for use: One capsule daily with meals or as directed.
General
Product # 2404-A
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Total Enzymes by Nutri-West label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Total Enzymes by Nutri-West
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease monograph & interactionsLipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsCellulase
Invertase
Diastase
In a base of pure Beet Root fiber
Interacts with861 drugs
Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...
In a base of pure Beet Root fiber monograph & interactionsTotal Enzymes by Nutri-West Drug Interactions
Total Enzymes contains 8 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 861 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Total Enzymes?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Total Enzymes interact with 861 drugs. Click any drug to see the details.
1 of the 8 ingredients in Total Enzymes interact with drugs. Each result below shows which ingredient is responsible. in a base of pure Beet Root fiber
Bazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Beclomethasone Dipropionate interactionBedaquilineSirturo
How Bedaquiline interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bedaquiline interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Belladonna, Ergotamine, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Belumosudil Mesylate interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Benzhydrocodone, Acetaminophen interactionBepridilVascor
How Bepridil interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bepridil interactionBexaroteneTargretin
How Bexarotene interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bexarotene interactionBictegravir, Emtricitabine, Tenofovir AlafenamideBiktarvy
How Bictegravir, Emtricitabine, Tenofovir Alafenamide interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bictegravir, Emtricitabine, Tenofovir Alafenamide interactionBoceprevirVictrelis
How Boceprevir interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Boceprevir interactionBosentanTracleer
How Bosentan interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bosentan interactionBosutinibBosulif
How Bosutinib interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bosutinib interactionBrentuximab VedotinAdcetris
How Brentuximab Vedotin interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Brentuximab Vedotin interactionBrexpiprazoleRexulti
How Brexpiprazole interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Brexpiprazole interactionBrigatinibAlunbrig
How Brigatinib interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Brigatinib interactionBromocriptineParlodel
How Bromocriptine interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Bromocriptine interactionBudenosidePulmicort Flexhaler, Pulmicort Turbuhaler
How Budenoside interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Budenoside interactionBudesonideEntocort EC, Eohilia, Pulmicort, Tarpeyo, Uceris
How Budesonide interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Budesonide interactionBuprenorphineBrixadi, Butrans, Sublocade, Subutex
How Buprenorphine interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Buprenorphine interactionBuprenorphine HydrochlorideBelbuca, Probuphine
How Buprenorphine Hydrochloride interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Buprenorphine Hydrochloride interactionBuprenorphine Hydrochloride, Naloxone HydrochlorideBunavail
How Buprenorphine Hydrochloride, Naloxone Hydrochloride interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Buprenorphine Hydrochloride, Naloxone Hydrochloride interactionBuprenorphine, NaloxoneCassipa, Zubsolv
How Buprenorphine, Naloxone interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Buprenorphine, Naloxone interactionBuprenorphine/naloxoneSuboxone
How Buprenorphine/naloxone interacts with Total Enzymes — through 1 ingredient. Tap an ingredient for the detail:
In A Base Of Pure Beet Root FiberCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full In A Base Of Pure Beet Root Fiber + Buprenorphine/naloxone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Total Enzymes with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
in a base of pure Beet Root fiber
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.
Antihypertensive Drugs
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Total Enzymes, from the product label.
Total Enzymes by Nutri-West: Common Questions
Does Total Enzymes by Nutri-West interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Total Enzymes is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Total Enzymes’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographBeet
Interacts with 861 drugsBeet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...
Read the full Beet monograph →Sources & How We Checked
Total Enzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 19 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Beet 14 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
- Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
- Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
- Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
- Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
- Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
- Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
- Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
- Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
- Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
- Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC