#8 Thy Ingredients & Drug Interactions
by Nutri-West
What is this page for?
First and foremost: checking #8 Thy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
#8 Thy is a dietary supplement by Nutri-West with 3 active ingredients. Its ingredients are commonly taken for anxiety and stress, trouble sleeping, nervous tension.Based on those ingredients, 1,168 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Uva Ursi extract, Parsley extract, Scullcap extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against #8 Thy by Nutri-West
Ask about any prescription or over-the-counter medication and we check it for interactions with #8 Thy by Nutri-West — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of #8 Thy by Nutri-West
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Nutri-West #8 Thy contains 3 active ingredients in liquid form: extracts of scullcap, parsley, and uva ursi. These are combined with alcohol and water as inactive ingredients.
Scullcap has traditionally been used for relaxation and nerve support, parsley for urinary and digestive wellness, and uva ursi historically for urinary tract health.
Does it work?
Couldn't assess
The evidence for these ingredients is limited. Scullcap's effectiveness for epilepsy, stress, stroke, spasticity, contact dermatitis, and premenstrual dysphoric disorder all have insufficient reliable evidence to rate.
Parsley's effectiveness for urinary tract infections, melasma, osteoarthritis, and skin cancer also lacks sufficient evidence. Uva ursi is rated possibly ineffective for urinary tract infections, while its effectiveness for bronchitis and benign prostatic hyperplasia has insufficient evidence.
In short, what these ingredients are traditionally marketed for hasn't been reliably proven.
How safe is it?
Well-documented data
Scullcap is generally well tolerated at low to moderate doses, though long-term safety data is limited and product quality varies. The most common side effects reported are cognitive impairment, digestive upset, and sedation—higher doses (200 mg or more) are more likely to trigger these.
One person taking a much larger dose (350 mg three times daily) reported vivid dreams; mild digestive disturbance occurred in about 9% of people at that dose. Parsley is safe in food amounts, but concentrated extracts in large quantities may carry serious risks including hemolytic anemia, low blood pressure, and kidney damage at very high doses; it should be avoided in pregnancy and avoided while breastfeeding.
Uva ursi is generally well tolerated at low doses and short-term, but can be toxic at high doses or with long-term use, causing nausea, vomiting, diarrhea, and stomach upset, and rarely serious effects like convulsions and collapse at very high doses; it should be avoided in pregnancy and while breastfeeding.
Meds to double-check
Moderate interaction found
Before taking Nutri-West #8 Thy, check with your pharmacist if you take blood thinners or antiplatelet drugs (Moderate); blood sugar medications (Moderate); sedatives, sleep aids, or CNS depressants including alcohol (Moderate); water pills or diuretics (Moderate); pentobarbital or other barbiturates (Moderate); lithium (Moderate); or medications processed through your liver's CYP1A2, CYP2C19, or CYP3A4 pathways (Moderate). If you take sirolimus, urinary acidifying agents, or aspirin, check as well.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This herbal blend may appeal to you if you're interested in traditional plant support and have no prescription medications that interact with it. However, if you take any blood thinners, diabetes drugs, sedatives, lithium, or medications processed through your liver, you should check your specific prescriptions before using this product.
Talk to your pharmacist before starting—especially if you're pregnant, breastfeeding, or on any regular medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about #8 Thy, straight from the product label.
| Brand | Nutri-West |
|---|---|
| Net contents | 1 Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Sep 24, 2021 |
| DSLD ID | 252328 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for #8 Thy by Nutri-West, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pure Tincture extract of | 0 NP | -- |
| Scullcap extract | 0 NP | -- |
| Parsley extract | 0 NP | -- |
| Uva Ursi extract | 0 NP | -- |
Other ingredients: Alcohol, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
For distribution by health care professionals only.
“When you want the best”
Storage
Store in a cool, dry place.
Precautions
Keep out of reach of children.
Tamper resistant outer seal Do not use if broken.
FDA Statement of Identity
Dietary Supplement
Formulation
Herbal Tincture
Formula
Contains 59% alcohol.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
#8 Thy by Nutri-West label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in #8 Thy by Nutri-West
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size5 Drop(s) Dosage formLiquid Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Pure Tincture extract of
Other (inactive) ingredients: Alcohol, Water. These complete the product’s ingredient list but are not active constituents.
#8 Thy by Nutri-West Drug Interactions
HelloPharmacist Interaction Report
Nutri-West #8 Thy is a liquid herbal blend with three active plant extracts, and it does interact with medications.
The most serious interaction involves parsley extract and blood thinners (anticoagulants) like warfarin—parsley contains vitamin K, which can theoretically decrease warfarin's effects, a Moderate-severity concern. Parsley also interacts at Moderate severity with a range of other medications: drugs that affect blood sugar (antidiabetes drugs), water pills (diuretics), medications processed through your liver's CYP1A2 pathway, pentobarbital and possibly other sedatives, sirolimus (an immune-suppressing drug), and theoretically with blood-thinning or clot-preventing drugs more broadly (antiplatelet drugs).
Read the full breakdown — every affected drug type, severity by severity
Scullcap extract carries a Moderate-severity interaction with CNS depressants (sedatives, sleep aids, pain medications, alcohol)—it can add to their drowsiness and mental-clarity effects. Uva ursi extract also has Moderate-severity interactions with several medication types: drugs processed through CYP2C19 or CYP3A4 liver pathways, lithium, and urinary acidifying agents, plus a Minor-severity interaction with drugs transported by P-glycoprotein.
One parsley interaction with aspirin is rated Minor.
Allogetherm these interactions span 1,169 individual medications. Use the search tool below to check your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against #8 Thy?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in #8 Thy interact with 1,168 drugs. Click any drug to see the details.
3 of the 3 ingredients in #8 Thy interact with drugs. Each result below shows which ingredient is responsible. Uva Ursi extract Parsley extract Scullcap extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Parsley ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Parsley ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley Extract + Abrocitinib interactionUva Ursi ExtractCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Uva Ursi Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Parsley ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Parsley Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Parsley ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with #8 Thy — through 1 ingredient. Tap an ingredient for the detail:
Scullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Aspirin interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Aspirin +1 Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Parsley ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley Extract + Acetaminophen, Aspirin, Caffeine interactionUva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Butalbital interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Butalbital, Caffeine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionScullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Butalbital, Codeine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Butalbital, Codeine interactionScullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Scullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionUva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionScullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Scullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Caffeine, Codeine interactionUva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Caffeine, Codeine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionScullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionScullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Acetaminophen, Caffeine, Isometheptene interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Caffeine, Pyrilamine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with #8 Thy — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionScullcap ExtractCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Scullcap Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Parsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionUva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with #8 Thy — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionParsley ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in #8 Thy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Uva Ursi extract
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Parsley extract
Anticoagulant/Antiplatelet Drugs
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Animal research suggests that parsley has antiplatelet effects.
Antidiabetes Drugs
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that parsley might decrease blood glucose. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Laboratory research suggests that parsley can inhibit CYP1A2.
Diuretic Drugs
Theoretically, parsley might enhance or interfere with the effects of diuretic drugs.
Animal research suggests that parsley seed extract increases urine elimination. Parsley leaf and root might also interfere with diuretic therapy due their purported aquaretic effects.
Pentobarbital (Nembutal)
Theoretically, parsley might increase the duration of pentobarbital effects.
Animal research suggests that parsley juice prolongs the action of pentobarbital, perhaps by decreasing cytochrome P450 levels. It is not known if this occurs in humans or if this applies to other barbiturates or sedatives.
Sirolimus (Rapamune)
Theoretically, large quantities of parsley might increase sirolimus levels.
In one case report, an adult female with a history of kidney transplant presented with elevated blood sirolimus levels, approximately 4-7 times greater than previous measures, after daily consumption of a juice containing approximately 30 grams of parsley for 7 days. Sirolimus levels returned to normal a week after the parsley juice was discontinued.
Warfarin (Coumadin)
Theoretically, large amounts of parsley leaf and root might decrease the effects of warfarin.
Parlsey contains vitamin K.
Aspirin
Theoretically, aspirin might increase the severity of allergic reactions to parsley.
In one case, severe urticaria and swelling were reported after taking aspirin with parsley in an individual with a known mild parsley allergy.
Scullcap extract
Cns Depressants
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Animal and clinical research suggests that skullcap can cause sedation and cognitive impairment.
Brand information
Manufacturer and brand details for #8 Thy, from the product label.
Nutri-West
See all Nutri-West products- Name
- Nutri-West
- Street Address
- P.O. Box 950
- City
- Douglas
- State
- WY
- ZipCode
- 82633
#8 Thy by Nutri-West: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind #8 Thy’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Skullcap
Interacts with 248 drugsAmerican skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally considered relatively safe for short-term us...
Read the full Skullcap monograph → Herb & supplement monographParsley
Interacts with 443 drugsParsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a diuretic and for digestion, but solid hu...
Read the full Parsley monograph → Herb & supplement monographUva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph →Sources & How We Checked
#8 Thy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 32 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Skullcap 3 references
- Wolfson P, Hoffmann DL. An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. Altern Ther Health Med 2003;9:74-8.
- Awad, R., Arnason, J. T., Trudeau, V., Bergeron, C., Budzinski, J. W., Foster, B. C., and Merali, Z. Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine. 2003;10(8):6 PubMed
- Brock C, Whitehouse J, Tewfik I, Towell T. American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers. Phytother Res 2014;28(5):692-8.
Parsley 21 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. DOI
- Eberhard P, Gall HM, Muller I, Moller R. Dramatic augmentation of a food allergy by acetylsalicylic acid. J Allergy Clin Immunol 2000;105:844 PubMed
- Tunali T, Yarat A, Yanardag R, et al. Effect of parsley (Petroselinum crispum) on the skin of STZ induced diabetic rats. Phytother Res 1999;13:138-41.. DOI
- Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
- Kreydiyyeh, S. I. and Usta, J. Diuretic effect and mechanism of action of parsley. J Ethnopharmacol 2002;79(3):353-357. PubMed
- Yanardag, R., Bolkent, S., Tabakoglu-Oguz, A., and Ozsoy-Sacan, O. Effects of Petroselinum crispum extract on pancreatic B cells and blood glucose of streptozotocin-induced diabetic rats. Biol Pharm Bull. 2003;26(8):1206-1210. PubMed
- Bolkent, S., Yanardag, R., Ozsoy-Sacan, O., and Karabulut-Bulan, O. Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study. Phytother.Res 2004;18(12):996-999.
- Ozsoy-Sacan, O., Yanardag, R., Orak, H., Ozgey, Y., Yarat, A., and Tunali, T. Effects of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats. J Ethnopharmacol 3-8-2006;104(1-2):175-181. PubMed
- Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem.Toxicol. 2006;44(9):147 PubMed
- Gadi, D., Bnouham, M., Aziz, M., Ziyyat, A., Legssyer, A., Legrand, C., Lafeve, F. F., and Mekhfi, H. Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats. J Ethnopharmacol 8-17-2009;125(1):170-174. PubMed
- Arslan S, Ucar R, Caliskaner AZ. A Cases of Near-fatal Anaphylaxis: Parsley "Over-use" as an Herbal Remedy. Med Arch. 2014;68(6):426-7.
- Foti C, Cassano N, Mistrello G, Amato S, Romita P, Vena GA. Contact urticaria to raw arugula and parsley. Ann Allergy Asthma Immunol. 2011 May;106(5):447-8. PubMed
- Farzaei MH, Abbasabadi Z, Ardekani MR, Rahimi R, Farzaei F. Parsley: a review of ethnopharmacology, phytochemistry and biological activities. J Tradit Chin Med. 2013;33(6):815-26. PubMed
- Kurtaran M, Koc NS, Aksun MS, Yildirim T, Yilmaz SR, Erdem Y. Petroselinum crispum, a commonly consumed food, affects sirolimus level in a renal transplant recipient: a case report. Ther Adv Drug Saf 2021;12:20420986211009358.
Uva Ursi 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
- Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
- Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
- Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC