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Dietary supplement

Transmax Tr Ingredients & Drug Interactions

by Biotivia

Transmax Tr label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Transmax Tr against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Transmax Tr is a dietary supplement by Biotivia with 1 active ingredient. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 98% Trans-Resveratrol Polygonum cuspidatum rhizome extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Transmax Tr by Biotivia

Ask about any prescription or over-the-counter medication and we check it for interactions with Transmax Tr by Biotivia — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Transmax Tr by Biotivia

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “98% Trans-Resveratrol Polygonum cuspidatum rhizome extract” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

Transmax Tr contains one active ingredient: 500 mg of trans-resveratrol, derived from Polygonum cuspidatum (Japanese knotweed) rhizome extract. Resveratrol is a polyphenol — a natural compound found in plants — that your body may use as an antioxidant.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Resveratrol's overall clinical evidence instead.

Moderate

Some clinical evidence supports Resveratrol for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Allergic rhinitis (hay fever) — rated "Possibly Effective" (Natural Medicines).
  • On file: Obesity — rated "Possibly Effective" (Natural Medicines).

The evidence for resveratrol is mixed. It appears possibly effective for obesity and allergic rhinitis (hay fever).

However, it is rated possibly ineffective for cardiovascular disease prevention and high cholesterol. The data we hold shows these findings; more research may refine our understanding.

The evidence, ingredient by ingredient Resveratrol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Resveratrol at typical supplement doses is generally well tolerated. At higher doses, the most common side effects are diarrhea, gastrointestinal discomfort, and loose stools.

Isolated cases have included headache, fatigue, and skin rash; one case of allergic contact dermatitis was reported with a cream containing resveratrol plus another ingredient, so causality is unclear. Long-term safety at high doses is not fully known.

Regarding pregnancy and breastfeeding, there isn't enough safety data to know either way whether concentrated resveratrol supplements are safe. Talk with your doctor or pharmacist before using this product if you're pregnant or nursing — they can weigh the risks and benefits for your situation.

Side effects, ingredient by ingredient Resveratrol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Resveratrol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 823 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Transmax Tr, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate concern — resveratrol may increase bleeding risk). Also flag any medication metabolized by CYP2C19, CYP1A2, CYP3A4, or CYP2E1 enzymes — resveratrol might raise its level, though human data is limited.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Transmax Tr might interest you if you're exploring resveratrol for obesity or hay fever and want a concentrated form. However, it's not a first choice for heart health or cholesterol.

The biggest caution is if you take blood thinners or medications metabolized by certain liver pathways — you'll need to clear it with your own doctor or pharmacist first, especially given the theoretical enzyme interactions and the lack of large human safety trials.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Transmax Tr, straight from the product label.

Brand Biotivia
Barcode (UPC) 094922463746
Net contents 30 Time Release Tablet(s)
Market status On market
Date entered into DSLD May 23, 2014
DSLD ID 33100
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Transmax Tr by Biotivia, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
094922463746
IngredientAmount% DV
98% Trans-Resveratrol Polygonum cuspidatum rhizome extract500 mg--
500 mg of Trans-Resveratrol500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Storage Instructions: Keep in a cool dark place or refrigerate.

FDA Statement of Identity

Dietary Supplement

General Statements

{QRC}

Conforms to recent scientific studies.

~Unique formulation and processing technology greatly increase potency.

~Manufactured in accordance with GMP standards for quality assurance. ~Protected against oxidation by nitrogen filled bubble packaging. ~Manufactured with proprietary Sustained release technology to provide enhanced bioavailability and assimilation versus standard time release tablets or capsules.

Committment to Excellence: Biotivia will not compromise in the relentless pursuit of human health.

LONGEVITY BIOCETICALS RELENTLESS DEVOTION TO HUMAN HEALTH

12 Hour Time Release Tablets

~Laboratory Grade ~Energy! ~Endurance! ~Weight Management!

Complements Celle Skin Care for Total Beauty and Health Support

Formulation

~Contains no animal products.

Other Ingredients: No silica, fillers or nonfunctional additives.

Suggested/Recommended/Usage/Directions

Usage Instructions: For 12 years of age or older take one or two tablets at least 1/2 hour before a meal.

Precautions

Pregnant or lactation women contact physician first.

Formula

Trans-Resveratrol Microencapsulated 500mg

Seals/Symbols

CERTIFIED VEGAN AVA American Vegetarian Association

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Transmax Tr by Biotivia label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Transmax Tr label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Transmax Tr by Biotivia

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

98% Trans-Resveratrol Polygonum cuspidatum rhizome extract

Interacts with
822 drugs
500 mg per serving

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

98% Trans-Resveratrol Polygonum cuspidatum rhizome extract monograph & interactions
Interaction report

Transmax Tr by Biotivia Drug Interactions

Want to check YOUR meds against Transmax Tr?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
822Drugs
822 Moderate

Ingredients driving the most interactions

98% Trans-Resveratrol Polygonum cuspidatum rhizome extract 822

Individual Drug Interactions

The ingredients in Transmax Tr interact with 822 drugs. Click any drug to see the details.

1 of the 1 ingredient in Transmax Tr interact with drugs. Each result below shows which ingredient is responsible. 98% Trans-Resveratrol Polygonum cuspidatum rhizome extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Transmax Tr with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

98% Trans-Resveratrol Polygonum cuspidatum rhizome extract5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
98% Trans-Resveratrol Polygonum cuspidatum rhizome extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Transmax Tr, from the product label.

Biotivia

See all Biotivia products
Name
Biotivia LLC
Street Address
2503D N. Harrison Street, #13
City
Arlington
State
VA
ZipCode
22207
Phone Number
1-866-459-2773
Web Address
www.Biotivia.com
Pharmacist Counseling Corner

Transmax Tr by Biotivia: Common Questions

Does Transmax Tr by Biotivia interact with any medications?
Yes. Based on its ingredients, Transmax Tr has a known interaction with 822 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Transmax Tr contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is trans-resveratrol and where does it come from?
Trans-resveratrol is a natural compound (polyphenol) extracted from Polygonum cuspidatum rhizome — commonly called Japanese knotweed. It's an antioxidant that your body may use to help manage oxidative stress.
Does resveratrol really work for weight loss or allergies?
The evidence suggests it's possibly effective for both obesity and hay fever (allergic rhinitis), based on the data we hold. However, it's rated possibly ineffective for heart disease and high cholesterol, so results vary depending on the condition.
What side effects might I notice?
Most common are digestive — diarrhea, loose stools, or stomach discomfort, especially at higher doses. Rare cases have included headache, fatigue, or skin rash, but long-term safety at high doses isn't fully established.
Is it safe to take this while I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist before using Transmax Tr in pregnancy or while nursing — they can give you personalized guidance based on your situation.
Does this interact with lots of medications?
Resveratrol can theoretically inhibit several liver enzymes, affecting how your body breaks down many drugs. The biggest real concern is with blood thinners. Check your exact medications using the search tool on this page or with your own healthcare provider — most interactions are theoretical and haven't been confirmed in humans.
Why does the label say '98% Trans-Resveratrol' but only 500 mg per dose?
The 98% refers to the purity of the extract itself — meaning the resveratrol content is very high in the source material. Your actual dose is 500 mg of that purified extract per serving.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Transmax Tr label
Go deeper

The Full Monographs Behind Transmax Tr’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Resveratrol

Interacts with 822 drugs

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...

Read the full Resveratrol monograph →
Sources

Sources & How We Checked

Transmax Tr's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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