Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Trenatestin Ingredients & Drug Interactions

by Anabolic Warfare

Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Trenatestin is a dietary supplement by Anabolic Warfare with 5 active ingredients. Its ingredients are commonly taken for muscle building and bodybuilding, increasing strength, athletic performance.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 19-NorAndrost-4-ene-3b-ol, 17-one. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Trenatestin by Anabolic Warfare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “19-NorDHEA Blend” is a proprietary blend — the label gives one combined amount (50 mg) without saying how much of each component you get.

Trenatestin contains 5 active ingredients. Three of them are 19-nor-DHEA compounds (19-NorAndrost-4-ene-3b-ol, 17-one; 19-NorAndrost-4-ene-3b-ol, 17-one Decanoate; and 19-NorAndrost-4-ene-3b-ol, 17-one Enanthate), which are sold as prohormones meant to support muscle and athletic performance.

It also contains Ajuga turkestanica extract and Rhaponticum carthamoides extract. The tablet includes inactive ingredients like microcrystalline cellulose, silica, and magnesium stearate.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: strength and power for muscle building.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise-induced muscle damage, Lean muscle mass, Body composition, Endurance.
  • The closest evidence on file: 19-nor-dhea is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: 19-nor-dhea is rated "Insufficient Reliable Evidence To Rate" for Muscle strength, Exercise-induced muscle damage.

The evidence we have doesn't establish that the 19-nor-DHEA compounds in this product work for athletic performance, muscle strength, weight management, or exercise recovery — each is rated as having insufficient reliable evidence to rate. Ajuga turkestanica extract is also rated insufficient evidence for cough.

We hold no effectiveness data for Rhaponticum carthamoides extract.

The evidence, ingredient by ingredient 19-nor-dhea Ajuga Nipponensis

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The 19-nor-DHEA compounds in this product are unproven hormonal prohormones with potential serious side effects and very little safety data. The safety data we hold advises against use during pregnancy and breastfeeding due to hormonal effects.

Ajuga turkestanica extract has limited safety information overall; the most common side effects reported are diarrhea, nausea, and vomiting. One case of acute kidney failure was reported after ingestion of a much larger dose in someone with pre-existing liver cirrhosis, though this is rare.

Side effects, ingredient by ingredient 19-nor-dhea Ajuga Nipponensis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — 19-nor-dhea.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Trenatestin, check with your doctor or pharmacist if you're on testosterone or any other androgens (male hormone therapies or prohormone products). Moderate risk of additive hormone-related side effects including mood changes and cardiovascular, kidney, or liver damage exists with these combinations.

We also cannot check Rhaponticum carthamoides extract, so confirm it with your pharmacist as well.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is a prohormone product with unproven effectiveness for muscle or athletic performance and little safety data behind it. If you take testosterone or any other androgens (hormone therapies, other prohormones), you need to talk with your doctor or pharmacist before starting — combining them could raise the risk of serious side effects.

Avoid it if you're pregnant or breastfeeding. Make your decision with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Trenatestin, straight from the product label.

Brand Anabolic Warfare
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 242013
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Trenatestin by Anabolic Warfare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
IngredientAmount% DV
19-NorDHEA Blend50 mg--
19-NorAndrost-4-ene-3b-ol, 17-one0 NP--
19-NorAndrost-4-ene-3b-ol, 17-one Decanoate0 NP--
19-NorAndrost-4-ene-3b-ol, 17-one Enanthate0 NP--
Ajuga turkestanica extract5 mg--
Rhaponticum carthamoides extract50 mg--

Other ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxy-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica, Silver Color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Savage Series

Formulation

Strength & Power Formula with Cyclosome Delivery Prohormone & Ecdysteroid master formula Uncharted strength gains Cyclosome Delivery: The most advanced oral administration technology ever developed

Seals/Symbols

Made in USA with pride cGMP Inspected Facility

FDA Statement of Identity

Dietary Supplement

See for yourself

Trenatestin by Anabolic Warfare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Trenatestin by Anabolic Warfare

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Ajuga turkestanica extract

No known
interactions
5 mg per serving

Ajuga nipponensis is a perennial plant from East Asia used in traditional medicine for cough and respiratory complaints. There is very little human re...

Ajuga turkestanica extract monograph & interactions

Rhaponticum carthamoides extract

50 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxy-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica, Silver Color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Trenatestin by Anabolic Warfare Drug Interactions

Want to check YOUR meds against Trenatestin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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8Drugs
8 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Trenatestin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

19-NorAndrost-4-ene-3b-ol, 17-one1 drug type · 8 drugs

Testosterone

19-nor-DHEA is purportedly converted to nandrolone and other androgens upon ingestion. Theoretically, taking 19-nor-DHEA with testosterone or other androgrens may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Trenatestin, from the product label.

Anabolic Warfare

See all Anabolic Warfare products
Name
Anabolic Warfare
Pharmacist Counseling Corner

Trenatestin by Anabolic Warfare: Common Questions

Does Trenatestin by Anabolic Warfare interact with any medications?
Yes. Based on its ingredients, Trenatestin has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Trenatestin contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The 19-nor-DHEA compounds and Ajuga turkestanica extract both carry safety data advising against use during pregnancy and breastfeeding due to hormonal effects and lack of safety information. Talk with your doctor before considering any supplement during pregnancy or while nursing.
Does this actually build muscle or improve athletic performance?
The evidence we hold doesn't show that the active ingredients in this product work for those purposes. Each one — the 19-nor-DHEA compounds and Ajuga turkestanica — is rated as having insufficient reliable evidence to support muscle strength, athletic performance, or exercise recovery claims.
What are the most common side effects?
Ajuga turkestanica extract has been reported to cause diarrhea, nausea, and vomiting. The 19-nor-DHEA compounds themselves have no documented adverse effects in our data, but they're unproven prohormones with little safety information overall.
Is this safe to take with my testosterone replacement therapy?
No — you should not combine this product with testosterone or other androgens without talking to your doctor first. The 19-nor-DHEA compounds theoretically convert to nandrolone and other androgens, which could create additive effects including mood changes and heart, kidney, or liver problems.
What is Ajuga turkestanica extract supposed to do?
We have insufficient evidence on file to establish what it does effectively. In our data it's evaluated only for cough, with insufficient reliable evidence to rate its use for that purpose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Trenatestin label
Sources

Sources & How We Checked

Trenatestin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

19-nor-dhea 4 references
  1. DHEA — MedlinePlus (NIH) Source
  2. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  4. FDA 101: Dietary Supplements — U.S. Food and Drug Administration Source

See these in context on the 19-nor-dhea monograph →

Ajuga Nipponensis 1 reference
  1. Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.

See these in context on the Ajuga Nipponensis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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