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Dietary supplement

Tri-Iodine 25 mg Ingredients & Drug Interactions

by Terry Naturally

Tri-Iodine 25 mg label
See full label image
Capsule Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tri-Iodine 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tri-Iodine 25 mg is a dietary supplement by Terry Naturally with 1 active ingredient. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tri-Iodine 25 mg by Terry Naturally

Ask about any prescription or over-the-counter medication and we check it for interactions with Tri-Iodine 25 mg by Terry Naturally — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tri-Iodine 25 mg by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Iodine” is listed as a grouped ingredient — the label gives one combined amount (25,000 mcg) without saying how much of each component you get.

Tri-Iodine contains 3 active ingredients — all forms of iodine: potassium iodide, sodium iodide, and molecular iodine — providing a total of 25 mg per capsule. The inactive ingredients are microcrystalline cellulose, hydroxypropyl methylcellulose, and silica, which help form and stabilize the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports strong cellular defense and hormone balance.
  • We looked for evidence on: Iodine deficiency, Radiation exposure, Thyroid cancer, thyroid function, metabolic health, immune support.
  • The strongest evidence on file: Iodine is rated "Likely Effective" for Radiation exposure (Natural Medicines).
  • Also on file: Iodine is rated "Likely Effective" for Iodine deficiency.
  • Also on file: Iodine is rated "Insufficient Reliable Evidence To Rate" for Thyroid cancer.

The data shows iodine is likely effective for preventing thyroid problems after radiation exposure and for correcting iodine deficiency. It's possibly effective for oral mucositis (painful mouth sores) and periodontitis (gum disease), though the evidence is less established for those uses.

The strength of the evidence depends on the condition you're addressing.

The evidence, ingredient by ingredient Iodine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Iodine is generally well tolerated at normal dietary amounts and when used with proper medical supervision. However, high doses can cause thyroid problems including goiter, hypothyroidism, or hyperthyroidism.

Common side effects from larger amounts include stomach upset, nausea, diarrhea, headache, metallic taste, and runny nose. Rarely, people can have a hypersensitivity reaction with symptoms like swelling, rash, fever, or joint pain.

Taking iodine chronically in very large amounts has caused acnelike skin lesions. In pregnancy, adequate iodine is important, but use only the amount your doctor recommends and avoid high-dose products.

Some iodine passes into breast milk, so follow medical guidance if you're nursing.

Side effects, ingredient by ingredient Iodine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Iodine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 7 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting, check your medications against these: lithium (mood disorders), antithyroid drugs (overactive thyroid), and amiodarone (heart rhythm). All three can have Moderate interactions with the iodine in this product.

If you take any of these, have your prescriber or pharmacist review it with you.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Consider this product if your doctor says you need iodine supplementation, especially for deficiency or after radiation exposure. Check with your pharmacist first if you take lithium, any antithyroid drugs, or amiodarone — these need monitoring.

Pregnant or nursing? Talk to your doctor or pharmacist about the right dose for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tri-Iodine 25 mg, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703190033
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2018
DSLD ID 177076
Product type Mineral
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tri-Iodine 25 mg by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
367703190033
IngredientAmount% DV
Iodine25000 mcg16667%
Potassium Iodide12430 mcg--
Sodium Iodide12430 mcg--
molecular Iodine140 mcg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Money-back guarantee

Supports strong cellular defense and hormone balance For your good health Terry

Three forms of iodine for optimum support Are you getting the iodine you need from diet alone? Iodine consumption has dropped 50% in the last 30 years. This “missing mineral” is critical for multiple reasons and reliable food sources can be difficult to find. Research has shown you need different forms of iodine to target different health systems. Potassium iodide Sodium iodide Molecular iodine

You can't live without iodine Every cell in your body requires iodine to keep it functioning properly. But each day, you are exposed to the iodine blockers: chlorine, bromide from bromated baked goods and soft drinks, and fluoride in tap water, just to name a few.

Breast, prostate, and colon health Hormone balance Menopause relief Healthy detoxification Cellular defense

BX19003.03

Formula

Tri-Iodine provides three beneficial forms of iodine, an essential trace element. Each capsule supplies 25 mg total iodine (equivalent to 25,000 mcg).

Star-K

Tri-iodine provides three beneficial forms of iodine to nourish multiple body systems: a blend of potassium iodide, sodium iodide, and molecular iodine. Three forms of iodine provide a wider spectrum of benefits: Potassium iodide and sodium iodide for hormone balance and immune health. Molecular iodine for breast, prostate, colon, and cellular health

Suggested/Recommended/Usage/Directions

Recommendations: 1 capsule daily with food. For long term use, consult a healthcare practitioner.

Precautions

If pregnant or nursing, consult a healthcare practitioner before using.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

JC 34 91 + 3(5,6)EP L19003.08

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Star-K

Formulation

Vegan

No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives. Non-GMO

Brand IP Statement(s)

Terry Naturally EuroPharma

Tri-Iodine can help. It supplies the crucial support you need for: Breast, uterine, prostate, and colon health Hormone balance and menopause relief Detoxification of environmental stressors Cellular defense throughout the body

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tri-Iodine 25 mg by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tri-Iodine 25 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tri-Iodine 25 mg by Terry Naturally

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Iodine

Interacts with
7 drugs
25000 mcg per serving

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...

Iodine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tri-Iodine 25 mg by Terry Naturally Drug Interactions

Want to check YOUR meds against Tri-Iodine 25 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
7Drugs
7 Moderate

Ingredients driving the most interactions

Iodine 7

Individual Drug Interactions

The ingredients in Tri-Iodine 25 mg interact with 7 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tri-Iodine 25 mg interact with drugs. Each result below shows which ingredient is responsible. Iodine

Each ingredient & the kinds of drugs it affects

For each ingredient in Tri-Iodine 25 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Iodine3 drug types · 7 drugs

Amiodarone (Cordarone)

Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Probable Evidence D
Lithium

Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.

Likelihood Probable Evidence D
Iodine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tri-Iodine 25 mg, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

Tri-Iodine 25 mg by Terry Naturally: Common Questions

Does Tri-Iodine 25 mg by Terry Naturally interact with any medications?
Yes. Based on its ingredients, Tri-Iodine 25 mg has a known interaction with 7 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tri-Iodine 25 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my iodine deficiency?
Yes — iodine is likely effective for correcting iodine deficiency according to our data. But have your levels tested and follow your doctor's dosing instructions, since too much iodine can cause thyroid problems.
Can I take this if I'm pregnant?
The data shows iodine is likely safe in pregnancy, but also possibly unsafe — so it's conflicting. Adequate iodine matters for your baby, but high doses can be a problem. Talk with your doctor or pharmacist to determine the right amount for you personally.
What are the most common side effects?
When taken in larger amounts, the most common side effects are stomach upset, diarrhea, nausea, headache, a metallic taste, and runny nose. At normal dietary doses with proper monitoring, iodine is well tolerated.
Is this safe if I'm breastfeeding?
The data shows iodine is likely safe but also possibly unsafe during breastfeeding — it's conflicting. Some iodine passes into breast milk, and excess can affect the baby. Follow your doctor's or pharmacist's guidance on dosing while nursing.
Can iodine cause thyroid problems?
Yes — high doses can trigger hypothyroidism (low thyroid) or hyperthyroidism (overactive thyroid), depending on your medical history. That's why dosing and monitoring matter, especially if you already have a thyroid condition or take thyroid medications.
What if I'm allergic to iodine?
Some people can be hypersensitive to iodine when taken by mouth, with symptoms like swelling, rash, fever, or joint pain. True iodine allergy is rare — often what's labeled an "iodine allergy" is actually a reaction to seafood proteins or contrast dye. If you've had a reaction before, tell your pharmacist before taking this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tri-Iodine 25 mg label
Go deeper

The Full Monographs Behind Tri-Iodine 25 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Iodine

Interacts with 7 drugs

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements help when you are truly deficient, but...

Read the full Iodine monograph →
Sources

Sources & How We Checked

Tri-Iodine 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Iodine 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  3. Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
  4. Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
  7. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  8. Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
  9. Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
  10. Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
  11. Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
  12. Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
  13. Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
  14. Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
  15. Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
  16. Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
  17. Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
  18. Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
  19. Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
  20. Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
  21. Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
  22. Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
  23. Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
  24. Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
  25. Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
  26. Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed

See these in context on the Iodine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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